Title: Optimization of extracorporeal membrane oxygenation therapy using near-infrared spectroscopy to assess changes in peripheral circulation: A pilot study
Authors: Chang, Hsiao-Huang
Chen, Yi-Chih
Huang, Chun-Jung
Kuo, Chia-Cheng
Wang, Yi-Min
Sun, Chia-Wei
交大名義發表
National Chiao Tung University
Keywords: extracorporeal membrane oxygenation;near-infrared spectroscopy;oxyhemoglobin;peripheral circulation;vasoactive medicine
Issue Date: 1-Jan-1970
Abstract: Near-infrared spectroscopy (NIRS) has been proposed as a noninvasive modality for detecting complications in patients undergoing extracorporeal membrane oxygenation (ECMO), and it can simultaneously reveal the global circulatory status of these patients. We optimized ECMO therapy on the basis of real-time peripheral NIRS probing. Three patients underwent venoarterial (VA) ECMO and one patient underwent venovenous (VV) ECMO. All patients received peripheral ECMO cannulation with routine distal perfusion catheter placement. We designed an experimental protocol to adjust ECMO blood flow over 1 hour. Hemodynamic responses were measured using NIRS devices attached to the calf at approximately 60% of the distance from the ankle to the knee. HbO(2)levels change substantially with adjustments in ECMO flow, and they are more sensitive than HHb levels and the tissue saturation index (TSI) are. NIRS for optimizing ECMO therapy may be reliable for monitoring global circulatory status.
URI: http://dx.doi.org/10.1002/jbio.202000116
http://hdl.handle.net/11536/155112
ISSN: 1864-063X
DOI: 10.1002/jbio.202000116
Journal: JOURNAL OF BIOPHOTONICS
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