標題: Nickel promoted switchable hydroheteroarylation of cyclodienes via C-H bond activation of heteroarenes
作者: Lee, Wei-Chih
Shih, Wei-Chin
Wang, Ting-Hsuan
Liu, Yuhua
Yap, Glenn P. A.
Ong, Tiow-Gan
應用化學系
Department of Applied Chemistry
關鍵字: Selective CH bond activation;Nickel;Hydroheteroarylation;Cyclic diene
公開日期: 1-Jul-2015
摘要: We demonstrated Ni-catalyzed switchable hydroheteroarylation of cyclic dienes via C-H bond activation of heteroarenes. In the presence of an N-heterocyclic carbene (NHC) ligand, hydroheteroarylation of cyclic diene with azole afforded alpha-alkenyl-azole, forging a Heck-like product without using any external oxidant. Conversely, changing the ligand to PCy3 would switch this reaction manifold to afford the other isomeric beta-alkenyl substituted azole. (C) 2015 Elsevier Ltd. All rights reserved.
URI: http://dx.doi.org/10.1016/j.tet.2015.03.066
http://hdl.handle.net/11536/127880
ISSN: 0040-4020
DOI: 10.1016/j.tet.2015.03.066
期刊: TETRAHEDRON
Volume: 71
Issue: 26-27
起始頁: 4460
結束頁: 4464
Appears in Collections:Articles