Three-Component and Nonclassical Reaction of Phosphines with Enynes and Aldehydes: Formation of gamma-Lactones Featuring alpha-Phosphorus Ylides

Abstract

Inverted carbenoid species, generated from attack of phosphines at the alpha(delta')-carbon of hex-2-en-4-ynedioic acid dialkyl esters, react with aldehydes to give gamma-lactones possessing an alpha-phosphorus ylide moiety.