Core/single-crystal-shell nanospheres for controlled drug release via a magnetically triggered rupturing mechanism

Abstract

Core/single-crystal-shell nanospheres are constructed from a poly-(N-vinyl2-pyrrolidone) (PVP)-modified silica core with an outer layer of single-crystal iron oxide shell. The nanospheres show outstanding release- and-zero-release characteristics via the addition and removal, respectively, of an external high-frequency magnetic field.