Synthesis and biological evaluation of novel angularly fused polycyclic coumarins

Title:	Synthesis and biological evaluation of novel angularly fused polycyclic coumarins
Authors:	Khan, IA Kulkarni, MV Gopal, M Shahabuddin, MS Sun, CM 應用化學系 Department of Applied Chemistry
Issue Date:	1-Aug-2005
Abstract:	In a three-step sequence, an array of angularly fused polycyclic heterocycles with coumarin, benzofuran and pyridine rings were synthesized from 4-bromomethylcoumarins and salicylonitrile. All the final compounds were fully characterized and screened for anti-microbial, anti-inflammatory and analgesic activities. Several compounds exhibited promising inflammation inhibiting and anti-microbial properties. (c) 2005 Elsevier Ltd. All rights reserved.
URI:	http://dx.doi.org/10.1016/j.bmcl.2005.05.063 http://hdl.handle.net/11536/13449
ISSN:	0960-894X
DOI:	10.1016/j.bmcl.2005.05.063
Journal:	BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume:	15
Issue:	15
Begin Page:	3584
End Page:	3587
Appears in Collections:	Articles

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