標題: Automatic method to compare the lanes in gel electrophoresis images
作者: Lin, Chih-Yang
Ching, Yu-Tai
Yang, Yun-Liang
生物科技學系
資訊工程學系
Department of Biological Science and Technology
Department of Computer Science
關鍵字: dynamic programming;gel electrophoresis (GE);lane comparison;matched filter;segmentation;watershed method
公開日期: 1-三月-2007
摘要: Gel electrophoresis (GE) is an important tool in genomic analysis. GE results are presented using images. Each image contains several vertical lanes. Each lane consists of several horizontal bands. Two lanes are identical if the relative positions of the bands are the same. We present a computer method designed to compare the lanes and identify identical lanes. This method, developed using many image-processing techniques, is applied to segment the lanes and bands in GE images. The lanes are then converted into "position vectors" that describe the positions of the bands. Comparing lanes becomes equivalent to comparing the position vectors. This method can accurately identify identical lanes, helping biologists to identify the identical lanes from many lanes with much less effort.
URI: http://dx.doi.org/10.1109/TITB.2006.875661
http://hdl.handle.net/11536/11094
ISSN: 1089-7771
DOI: 10.1109/TITB.2006.875661
期刊: IEEE TRANSACTIONS ON INFORMATION TECHNOLOGY IN BIOMEDICINE
Volume: 11
Issue: 2
起始頁: 179
結束頁: 189
顯示於類別:期刊論文


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