標題: An Intelligent Digital Microfluidic Processor for Biomedical Detection
作者: Lai, Kelvin Yi-Tse
Yang, Yu-Tao
Lee, Chen-Yi
電子工程學系及電子研究所
Department of Electronics Engineering and Institute of Electronics
關鍵字: Microfluidic;Biomedical Processor;Capacitive sensing;Bioassays;Biochip;EWOD;Lab-chip
公開日期: 1-一月-2015
摘要: An intelligent digital microfluidic processor for biomedical detection is presented. This potential architecture solves lots of traditional development bottlenecks to implement the easy-to-control, easy-to-monitor, system automation and high accuracy for bioassay detection purposes. The proposed processor integrates the functions of microfluidic actuation, droplet location readback and high sensitivity measurement window to demonstrate a novel prototype for personalized medicine. Furthermore, the droplet location map and reaction behaviors are visible on a 2-dimentional (2D) graphical user-interface due to the micro electrode dot array (MEDA) architecture and capacitive sensing technology, and hence system automation is achievable. Fabricated in standard 0.35 mu m CMOS process, this work integrates 900 microelectrodes with measurement window in 3.2 mm(2), where the high sensitivity capacitive readout circuit occupies only 0.048 mm(2). Measurement results show that microdroplet actuation and 2D location map are activated under 1KHz. In addition, the function of digital signal extraction, processing, as well as statistical analysis can be operated under 1 MHz respectively.
URI: http://dx.doi.org/10.1007/s11265-014-0939-3
http://hdl.handle.net/11536/124242
ISSN: 1939-8018
DOI: 10.1007/s11265-014-0939-3
期刊: JOURNAL OF SIGNAL PROCESSING SYSTEMS FOR SIGNAL IMAGE AND VIDEO TECHNOLOGY
Volume: 78
起始頁: 85
結束頁: 93
顯示於類別:期刊論文