Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yu, Shiang-Yi | en_US |
dc.contributor.author | Hsu, Chen-Yi | en_US |
dc.contributor.author | Chen, Wei-Chieh | en_US |
dc.contributor.author | Wei, Ling-Fang | en_US |
dc.contributor.author | Wu, Shu-Pao | en_US |
dc.date.accessioned | 2015-12-02T02:59:21Z | - |
dc.date.available | 2015-12-02T02:59:21Z | - |
dc.date.issued | 2014-06-01 | en_US |
dc.identifier.issn | 0925-4005 | en_US |
dc.identifier.uri | http://dx.doi.org/10.1016/j.snb.2014.01.121 | en_US |
dc.identifier.uri | http://hdl.handle.net/11536/128092 | - |
dc.description.abstract | A coumarin-based fluorometric probe, HS1, has been successfully developed for highly sensitive and selective detection of hypochlorous acid (HOCl). The probe is based on the specific HOCl-promoted oxidation of oxime. The reaction is accompanied by a 7-fold increase in the fluorescent quantum yield (from 0.03 to 0.21). The fluorescence intensity of the reaction between HOCl and HS1 shows a good linearity in the HOCl concentration range of 1-20 mu M and a low detection limit of 25 nM (S/N = 3). In addition, confocal fluorescence microscopy imaging using RAW264.7 macrophages demonstrates that the HS1 probe could be an efficient fluorescent probe for HOCl in living cells. (C) 2014 Elsevier B.V. All rights reserved. | en_US |
dc.language.iso | en_US | en_US |
dc.subject | Hypochlorous acid | en_US |
dc.subject | Fluorescent probe | en_US |
dc.subject | Coumarin | en_US |
dc.subject | Bioimaging | en_US |
dc.title | A hypochlorous acid turn-on fluorescent probe based on HOCl-promoted oxime oxidation and its application in cell imaging | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1016/j.snb.2014.01.121 | en_US |
dc.identifier.journal | SENSORS AND ACTUATORS B-CHEMICAL | en_US |
dc.citation.volume | 196 | en_US |
dc.citation.spage | 203 | en_US |
dc.citation.epage | 207 | en_US |
dc.contributor.department | 應用化學系 | zh_TW |
dc.contributor.department | Department of Applied Chemistry | en_US |
dc.identifier.wosnumber | WOS:000333652400028 | en_US |
dc.citation.woscount | 13 | en_US |
Appears in Collections: | Articles |