標題: | Ultrahigh-Density 256-Channel Neural Sensing Microsystem Using TSV-Embedded Neural Probes |
作者: | Huang, Yu-Chieh Huang, Po-Tsang Wu, Shang-Lin Hu, Yu-Chen You, Yan-Huei Chen, Jr-Ming Huang, Yan-Yu Chang, Hsiao-Chun Lin, Yen-Han Duann, Jeng-Ren Chiu, Tzai-Wen Hwang, Wei Chen, Kuan-Neng Chuang, Ching-Te Chiou, Jin-Chern 生物科技學系 電子工程學系及電子研究所 電機工程學系 電控工程研究所 Department of Biological Science and Technology Department of Electronics Engineering and Institute of Electronics Department of Electrical and Computer Engineering Institute of Electrical and Control Engineering |
關鍵字: | Electrocorticography (ECoG);local field potential (LFP);microsystem;probe;somatosensory evoked potential (SSEP);TSV-embedded mu-needles |
公開日期: | 1-十月-2017 |
摘要: | Highly integrated neural sensing microsystems are crucial to capture accurate signals for brain function investigations. In this paper, a 256-channel neural sensing microsystem with a sensing area of 5 x 5 mm(2) is presented based on 2.5-D through-silicon-via (TSV) integration. This microsystem composes of dissolvable mu-needles, TSV-embedded mu-probes, 256-channel neural amplifiers, 11-bit area-power-efficient successive approximation register analog-to-digital converters, and serializers. This microsystem can detect 256 electrocorticography and local field potential signals within a small area of 5 mm x 5 mm. The neural amplifier realizes 57.8 dB gain with only 9.8 mu W per channel. The overall power of this microsystem is only 3.79mW for 256-channel neural sensing. A smaller microsystem with dimension of 6 mm x 4 mm has been also implanted into rat brain for somatosensory evoked potentials (SSEPs) recording by using contralateral and ipsilateral electrical stimuli with intensity from 0.2 to 1.0 mA, and successfully observed different SSEPs from left somatosensory cortex of a rat. |
URI: | http://dx.doi.org/10.1109/TBCAS.2017.2669439 http://hdl.handle.net/11536/144325 |
ISSN: | 1932-4545 |
DOI: | 10.1109/TBCAS.2017.2669439 |
期刊: | IEEE TRANSACTIONS ON BIOMEDICAL CIRCUITS AND SYSTEMS |
Volume: | 11 |
起始頁: | 1013 |
結束頁: | 1025 |
顯示於類別: | 期刊論文 |