標題: A novel nanomolar highly selective fluorescent probe for imaging mercury (II) in living cells and zebrafish
作者: Liu, Yen-Yu
Naha, Sanay
Thirumalaivasan, Natesan
Velmathi, Sivan
Wu, Shu-Pao
應用化學系
Department of Applied Chemistry
關鍵字: Hg2+;Pyrene;Bioimaging;Zebrafish
公開日期: 20-十二月-2018
摘要: A novel fluorescent probe, PES, which contains a bisethylsulfane moiety, displayed high specificity for Hg2+ detection. With Hg2+, PES showed significant blue fluorescence enhancement, while the metal ions Al3+, Ag+, Cr3+, Ca2+, Cu2+, Co2+, Cd2+, Fe3+, Fe2+, Mn2+, Mg2+, Ni2+, Zn2+, and Pb2+ exhibited only negligible fluorescence change. PES has been found to be an effective quantitative detector (LOD, 57 nM) for Hg2+ in semi-aqueous medium based on the Hg2+-induced removal of bisethylsulfane. It resulted in a turn-on blue fluorescence response. The fluorescence enhancement induced by Hg2+ was observed over the pH range of 4-10. Our fluorescence cell-imaging experiments revealed the applicability of the new probe, PES, to be a reliable and effective fluorescent marker for Hg2+ in living cells.
URI: http://dx.doi.org/10.1016/j.snb.2018.09.015
http://hdl.handle.net/11536/148595
ISSN: 0925-4005
DOI: 10.1016/j.snb.2018.09.015
期刊: SENSORS AND ACTUATORS B-CHEMICAL
Volume: 277
起始頁: 673
結束頁: 678
顯示於類別:期刊論文