標題: | Microfluidics and Nanomaterial-based Technologies for Circulating Tumor Cell Isolation and Detection |
作者: | Cheng, Sheng-Jen Hsieh, Kuan Yu Chen, Shiue-Luen Chen, Chong-You Huang, Chien-Yu Tsou, Hung-I Kumar, Priyank V. Hsieh, Jason Chia-Hsun Chen, Guan-Yu 生物科技學系 生醫工程研究所 電機學院 Department of Biological Science and Technology Institute of Biomedical Engineering College of Electrical and Computer Engineering |
關鍵字: | liquid biopsy;circulating tumor cells;microfluidic;graphene oxide;surface modification |
公開日期: | 1-四月-2020 |
摘要: | Cancer has been one of the leading causes of death globally, with metastases and recurrences contributing to this result. The detection of circulating tumor cells (CTCs), which have been implicated as a major population of cells that is responsible for seeding and migration of tumor sites, could contribute to early detection of metastasis and recurrences, consequently increasing the chances of cure. This review article focuses on the current progress in microfluidics technology in CTCs diagnostics, extending to the use of nanomaterials and surface modification techniques for diagnostic applications, with an emphasis on the importance of integrating microchannels, nanomaterials, and surface modification techniques in the isolating and detecting of CTCs. |
URI: | http://dx.doi.org/10.3390/s20071875 http://hdl.handle.net/11536/154613 |
DOI: | 10.3390/s20071875 |
期刊: | SENSORS |
Volume: | 20 |
Issue: | 7 |
起始頁: | 0 |
結束頁: | 0 |
顯示於類別: | 期刊論文 |