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dc.contributor.authorLai, Sheng-Fengen_US
dc.contributor.authorChien, Chia-Chien_US
dc.contributor.authorChen, Wen-Changen_US
dc.contributor.authorChen, Hsiang-Hsinen_US
dc.contributor.authorChen, Yi-Yunen_US
dc.contributor.authorWang, Cheng-Liangen_US
dc.contributor.authorHwu, Y.en_US
dc.contributor.authorYang, C. S.en_US
dc.contributor.authorChen, C. Y.en_US
dc.contributor.authorLiang, K. S.en_US
dc.contributor.authorPetibois, Cyrilen_US
dc.contributor.authorTan, Hui-Ruen_US
dc.contributor.authorTok, Eng-Soonen_US
dc.contributor.authorMargaritondo, G.en_US
dc.date.accessioned2014-12-08T15:30:01Z-
dc.date.available2014-12-08T15:30:01Z-
dc.date.issued2013-05-01en_US
dc.identifier.issn0734-9750en_US
dc.identifier.urihttp://dx.doi.org/10.1016/j.biotechadv.2012.05.005en_US
dc.identifier.urihttp://hdl.handle.net/11536/21502-
dc.description.abstractAn original synthesis method based on X-ray irradiation produced gold nanoparticles (AuNPs) with two important properties for biomedical research: intense visible photoluminescence and very high accumulation in cancer cells. The nanoparticles, coated with MUA (11-mercaptoundecanoid acid), are very small (1.4 nm diameter); the above two properties are not present for even slightly larger sizes. The small MUA-AuNPs are non-cytotoxic (except for very high concentrations) and do not interfere with cancer cell proliferation. Multimodality imaging using visible light fluorescence and X-ray microscopy is demonstrated by tracing the nanoparticle-loaded tumor cells. (C) 2012 Elsevier Inc. All rights reserved.en_US
dc.language.isoen_USen_US
dc.subjectPhotoluminescenceen_US
dc.subjectAu nanoparticlesen_US
dc.subjectX-ray imagingen_US
dc.subjectCellular uptakeen_US
dc.subjectRadiation synthesisen_US
dc.subjectCytotoxicityen_US
dc.subjectTumor developmenten_US
dc.titleVery small photoluminescent gold nanoparticles for multimodality biomedical imagingen_US
dc.typeArticle; Proceedings Paperen_US
dc.identifier.doi10.1016/j.biotechadv.2012.05.005en_US
dc.identifier.journalBIOTECHNOLOGY ADVANCESen_US
dc.citation.volume31en_US
dc.citation.issue3en_US
dc.citation.spage362en_US
dc.citation.epage368en_US
dc.contributor.department電子物理學系zh_TW
dc.contributor.departmentDepartment of Electrophysicsen_US
dc.identifier.wosnumberWOS:000317441900002-
Appears in Collections:Conferences Paper


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