A Telescoping Synthesis of Chimeric Polyheterocycles through a Piperidine-Mediated Multicomponent Reaction

標題:	A Telescoping Synthesis of Chimeric Polyheterocycles through a Piperidine-Mediated Multicomponent Reaction
作者:	Lee, Chia-Hsin Hsu, Wei-Shun Chen, Chih-Hau Sun, Chung-Ming 應用化學系 Department of Applied Chemistry
關鍵字:	Synthetic methods;Multicomponent reactions;Telescoping synthesis;Nitrogen heterocycles;Schiff bases
公開日期:	1-四月-2013
摘要:	A new piperidine-catalyzed Groebke-Bienayme-Blackburn (GBB) multicomponent reaction of 2-aminobenzimidazoles, methyl 2-formylbenzoate, and isocyanides has been explored. A facile and straightforward postmodification leads to isoquinolinone-embedded imidazo[1,2-a]benzimidazoles. Insight into a plausible mechanism is discussed and supported by X-ray crystal structure analysis.
URI:	http://dx.doi.org/10.1002/ejoc.201201645 http://hdl.handle.net/11536/22395
ISSN:	1434-193X
DOI:	10.1002/ejoc.201201645
期刊:	EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume:
Issue:	11
起始頁:	2201
結束頁:	2208
顯示於類別：	期刊論文

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