標題: | A Pyrene-based Highly Selective Turn-on Fluorescent Chemosensor for Iron(III) Ions and its Application in Living Cell Imaging |
作者: | Chung, Peter Kun Liu, Shi-Rong Wang, Hsuan-Fu Wu, Shu-Pao 應用化學系 Department of Applied Chemistry |
關鍵字: | Sensors;Iron;Pyrene;Imaging agents |
公開日期: | 1-十一月-2013 |
摘要: | A new pyrene-based chemosensor (1) exhibits excellent selectivity for Fe3+ ions over a wide range of tested metal ions Ag+, Ca2+, Cd2+, Co2+, Cu2+, Fe2+, Hg2+, K+, Mg2+, Mn2+, Ni2+, Pb2+, and Zn2+. The binding of Fe3+ to chemosensor 1 produces an emission band at 507 nm due to the formation of a Py-Py* excimer that is induced by Fe3+-binding. The binding ratio of 1-Fe3+ was determined to be 1:1 from a Job plot. The association constant of 1-Fe3+ complexes was found to be 1.27 x 10(4) M-1 from a Benesi-Hildebrand plot. In addition, fluorescence microscopy experiments show that 1 can be used as a fluorescent probe for detecting Fe3+ in living cells. |
URI: | http://dx.doi.org/10.1007/s10895-013-1242-6 http://hdl.handle.net/11536/22952 |
ISSN: | 1053-0509 |
DOI: | 10.1007/s10895-013-1242-6 |
期刊: | JOURNAL OF FLUORESCENCE |
Volume: | 23 |
Issue: | 6 |
起始頁: | 1139 |
結束頁: | 1145 |
顯示於類別: | 期刊論文 |