Browsing by Author "Akai, Takayuki"

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Inverse Streamline Mapping for Finding an Optimum Medicine Injection Point in Micro Chamber
(2018-01-01)
Takayama, Toshio
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Akai, Takayuki
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Tsai, Chia-Hung Dylan
;
Kaneko, Makoto
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機械工程學系
This paper proposes a new concept of "Inverse Streamline Mapping for Finding an Optimum Medicine Injection Point in Micro Chamber". We search the streamlines from the target chamber to the point in the cross-section at the entrance, so that we can find an optimum medicine injection point. The optimum condition is that all streamlines in target chamber start from the smallest cross-sectional area for a given microfluidic chip. The idea is enhanced by designing the microfluidic channel with the desirable streamline mapping between the target chamber and the cross-section at the entrance. We show that the liquid supplied at a particular point can fully cover the chamber in both simulations and experiments.
Virtual vortex gear: Unique flow patterns driven by microfluidic inertia leading to pinpoint injection
(2018-05-01)
Tsai, Chia-Hung Dylan
;
Takayama, Toshio
;
Shimozyo, Yuta
;
Akai, Takayuki
;
Kaneko, Makoto
An interesting phenomenon that vortices are sequentially generated on a microfluidic chip is investigated in this paper. The direction of every two adjacent vortices is opposite to each other, like a set of gears, and thus is named virtual vortex gear (VVG). Both experiments and computational simulations were conducted in order to make clear the mechanism of VVG. The experimental results show that only the flow from a particular point would form vortices and enter the target chamber. A technique of inverse mapping is proposed based on the phenomenon and it demonstrates that only a pinpoint injection is sufficient to control the contents of a microfluidic chamber. VVG can significantly reduce the volume of chemical usage in biological research and has potential for other on-chip applications, such as mixing and valving. Published by AIP Publishing.