Browsing by Author "Bando, Takanobu"

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Electron-Transfer-Induced Intramolecular Heck Carbonylation Reactions Leading to Benzolactones and Benzolactams
(2018-08-01)
Fukuyama, Takahide
;
Bando, Takanobu
;
Ryu, Ilhyong
;
應用化學系
;
Department of Applied Chemistry
A metal-catalyst-free intramolecular Heck carbonylation reaction of benzyl alcohols and benzyl amines with carbon monoxide under heating at 250 degrees C affords the corresponding benzolactones and benzolactams in good to excellent yields. A hybrid radical/ionic chain mechanism, involving electron transfer from radical anions generated by nucleophilic attack of alcohols or amines on intermediate acyl radicals, is proposed.