Browsing by Author "Chang, Chiu-Ching"

Now showing 1 - 1 of 1

Joined use of oxazolidinone and desymmetric amino protection: a new strategy for protection of glucosamine
(2010-04-07)
Lin, Shih-Che
;
Chao, Chin-Sheng
;
Chang, Chiu-Ching
;
Mong, Kwok-Kong T.
;
應用化學系
Joined use of N-benzyl oxazolidinone and N-benzyl-N-benzyloxycarbonyl (N-BnCbz) desymmetric amino-protecting function is reported. The new synthetic approach enables the facile preparation of type I and type 2 LacNAc disaccharides in satisfactory yields. One-pot deprotection of N-BnCbz and O-benzyl ether is achieved by hydrogenolysis under mild conditions. (C) 2010 Elsevier Ltd. All rights reserved.