Browsing by Author "Chen, Chang-Ting"

Now showing 1 - 5 of 5

A VLSI Implementation of Variation-Free PUF-based Processor for RFID Applications
(2013-01-01)
Dung, Lan-Rong
;
Chen, Chang-Ting
;
電機資訊學士班
;
Undergraduate Honors Program of Electrical Engineering and Computer Science
The Physically Unclonable Function (PUF) has been presented to defend physical attacks for RFID authentication. The silicon PUF employs difference of gate and wire delays on silicon chip to protect hardware copies of RFID. Because of the process variation in IC manufacturing, each silicon chip has different delays for gates and wires and, thus, the PUF-based encryption on each chip has different output even though the logic design is the same as the others. Research has been focusing on low-cost PUF implementation with a chain of logic blocks. However, some operating variations such as power-supply voltage and temperature variations might cause the failure of authentication. This paper presents a variation-free PUF-based processor with error control coding (ECC) technology. We used the ECC encoder to generate parity code for variation compensation. Therefore, our chip can generate a variation-free PUF encryption for RFID application. The chip is implemented by TSMC 0.18um CMOS process. As shown in the results, the chip area is as small as 0.83 mm<^>2 and its power dissipation is 87 uW.
Laminar shear flow increases hydrogen sulfide and activates a nitric oxide producing signaling cascade in endothelial cells
(2015-09-04)
Huang, Bin
;
Chen, Chang-Ting
;
Chen, Chi-Shia
;
Wang, Yun-Ming
;
Hsieh, Hsyue-Jen
Laminar shear flow triggers a signaling cascade that maintains the integrity of endothelial cells (ECs). Hydrogen sulfide (H2S), a new gasotransmitter is regarded as an upstream regulator of nitric oxide (NO). Whether the H2S-generating enzymes are correlated to the enzymes involved in NO production under shear flow conditions remains unclear as yet. In the present study, the cultured ECs were subjected to a constant shear flow (12 dyn/cm(2)) in a parallel flow chamber system. We investigated the expression of three key enzymes for H2S biosynthesis, cystathionine-gamma-Iyase (CSE), cystathionine-beta-synthase (CBS), and 3-mercapto-sulfurtransferase (3-MST). Shear flow markedly increased the level of 3-MST. Shear flow enhanced the production of H2S was determined by NBD-SCN reagent that can bind to cysteine/homocystein. Exogenous treatment of NaHS that can release gaseous H2S, ECs showed an increase of phosphorylation in Akt(S473), ERKT202/Y204 and eNOS(S1177). This indicated that H2S can trigger the NO-production signaling cascade. Silencing of CSE, CBS and 3-MST genes by siRNA separately attenuated the phosphorylation levels of Akt(S423) and eNOS(S1177) under shear flow conditions. The particular mode of shear flow increased H2S production. The interplay between H2S and NO-generating enzymes were discussed in the present study. (C) 2015 Elsevier Inc. All rights reserved.
Optical Technique for Estimating Cerebral Perfusion Pressure
(2015)
Chen, Chang-Ting
;
Liao, Yi-Chien
;
Lai, Chien-Fu
;
Lin, Bor-Shyh
;
Wang, Che-Chuan
It is important to avoid secondary brain injury after Traumatic brain injury (TBI) in clinical. Cerebral perfusion pressure (CPP) is associated with blood flow into the brain, and indirectly reflects the cerebral ischemia and oxygenation. However, it is invasive and is inconvenient for continuous monitoring. Recently, near infrared spectroscopy (NIRS) has been widely applied for monitoring cerebral ischemia and hypoxia. In this study, we developed a wireless NIRS system to monitor rat\'s brain in different impact strengths of trauma. Commercial ICP and MAP devices were also used to compare with NIRS parameters under TBI. The Experimental results show all of Delta CPP, Delta[HbO(2)], Delta[HbT], and Delta[HbR] were inversely proportional to the increased impact strengths, and the correlations between Delta CPP, and Delta[HbO(2)] and Delta[HbT] are high. Hence NIRS system may be useful for estimating the level of cerebral perfusion pressure non-invasively.
Quantitative Real-Time Assessment for Feeding Skill of Preterm Infants
(2017-06-01)
Chen, Chang-Ting
;
Wang, Lin-Yu
;
Wang, Yu-Lin
;
Lin, Bor-Shyh
;
影像與生醫光電研究所
Nutritive sucking is the approach of obtaining primary food for newborns within six months. However, completing the precise coordination of sucking-swallowing-respiratory actions under oral feeding is usually difficult for preterm infants and may affect the body and neural development of the premature infant. For this reason, how to obtain the quantitatively physiological information related to oral feeding is useful for physicians making more accurate clinical diagnoses for oral feeding disorders. However, there is still lack of monitoring systems for evaluating the feeding skill of infants quantitatively and objectively. The assessment of the feeding skill or the diagnosis of oral-feeding disorders still depends on the clinical experience of medical staffs. In this study, a novel wireless monitoring system is proposed to evaluate the feeding behavior of infants quantitatively and objectively and analyze the characteristics of these actions under oral feeding. Here, a specific feeding bottle and an optical probe are also designed and successfully applied to noninvasively monitor the sucking and respiratory actions, and a microphone is also applied to monitor the swallowing action. From the experimental results, the sucking and swallowing rate increases and the respiratory rate decreases with the increase of the infant age. Moreover, the duration increases and the interval of sucking-action sequence decreases with the increase of the infant age respectively. The proposed system successfully assesses the feeding behavior of preterm infants and may provide an objective evaluation tool for oral feeding ability and identifying the risk of infant developmental delay in the future.
Wireless Monitoring System for Oral-Feeding Evaluation of Preterm Infants
(2015-10-01)
Chen, Chang-Ting
;
Wang, Yu-Lin
;
Wang, Chen-An
;
Ko, Mei-Ju
;
Fang, Wai-Chi
The oral feeding disorder is one of the important indicators for the high risk group of neurodevelopment delay. The procedure of oral feeding requires the coordination of sucking, swallowing, and breathing activities, and it is the most complex sensorimotor process for newborn infants. Premature infants often uneasily complete the procedure of oral feeding. However, the evaluation of the oral feeding disorders and severity are usually dependent on the subjective clinical experience of the physician. Monitoring the sucking-swallowing-breathing activities directly is difficult for preterm infants. In this study, a wireless monitoring system for oral-feeding evaluation of full term and preterm infants was proposed to objectively and quantitatively evaluate the coordination of suck-swallow-respiration function during oral feeding. Moreover, the ratios of the swallowing and breathing event numbers to the sucking event number were defined to evaluate the coordination of suck-swallow-respiration function during oral feeding. Finally, the system performance was validated and the coordination of suck-swallow-respiration function for full term and preterm infants during oral feeding was also investigated.