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Browsing by Author "Chen, Li-Chia"

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    AN AFFINITY SENSOR IMPROVED BY EWOD ACTUATOR-BASED MICROFLUIDIC CHIP
    (2009-12-01)
    Liu, Chin-Wei
    ;
    Lin, Chi-Chang
    ;
    Chen, Li-Chia
    ;
    Fan, Shih-Kang
    ;
    Chang, Hsien-Chang
    We propose an improved immunoassay method with EWOD-based microfluidic biochip. Electro-wetting on dielectric (EWOD) is based on contact angle-changed phenomenon of droplet on the channel surface. The reactant-containing droplet can be moved from reservoir to a modified electrode area, which a stir function can be provided by controlling AC electro-osmosis flow (ACEOF). The immunochemistry reaction takes place on our modified area via electro-wetting actuation, and the signal from fluorescent or electrochemical impedance spectroscopy (EIS) was used to confirm the performance of designed element.