Browsing by Author "Chen, Pin-Wen"

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An 1.97 mu W/Ch 65nm-CMOS 8-Channel Analog Front-End Acquisition Circuit with Fast-Settling Hybrid DC Servo Loop for EEG Monitoring
(2018-01-01)
Chen, Pin-Wen
;
Huang, Chi-Wei
;
Wu, Chung-Yu
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電子工程學系及電子研究所
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Department of Electronics Engineering and Institute of Electronics
In this paper, a 65nm-CMOS 8-channel Analog Front-End (AFE) acquisition circuit is designed and fabricated for long term EEG monitoring. The Capacitively-Coupled Chopper Instrumentation Amplifier (CCCIA) with chopper modulation is used to amplify input EEG signals and suppress flicker noise. To realize low high-pass corner and large Electrode DC Offset (EDO) rejection ability, a fast-settling Hybrid DC Servo Loop (HDSL) is proposed here. It contains Digital DSL (DDSL) and Analog DSL (ADSL) to achieve better trade-off among power consumption, area, and hardware complexity. An energy-efficient 10-bit SAR ADC with offset-calibration comparator is integrated for accurate A/D conversion. The chip is fabricated in 65nm CMOS technology. The measured overall power dissipation of the acquisition circuit is 1.97 mu W per channel. The input-referred noise of AFE Amplifier (AFEA) is 0.7 mu V in pass band, and the Noise Efficient Factor (NEF) of the CCCIA is 1.99. The measured HDSL calibration time is 125ms. The fabricated SAR ADC has the power consumption of 0.85 mu W under 1V supply and the SNDR of 59.8dB at 100kS/s with the Nyquist input frequency. This chip can record EEG signals successfully and the recorded signal has been verified by NeruScan SynAmps RT 64-channel amplifiers.
Effects of Music on Immunity and Physiological Responses in Healthcare Workers: A Randomized Controlled Trial
(2013-04-01)
Lai, Hui-Ling
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Liao, Kuang-Wen
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Huang, Chiung-Yu
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Chen, Pin-Wen
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Peng, Tai-Chu
Research-based evidence supports the effectiveness of soothing music in improving stress-related psycho-physiological indices in a clinical setting. However, there is currently insufficient scientific knowledge of the effects of music on immune markers of stress in humans. Therefore, the aims of the study were to compare the effects of music and quiet rest on the levels of interleukin-6 (IL-6), tumour necrosis factor- (TNF-), interleukin-10 (IL-10), heart rate and mean arterial pressure among healthcare workers. By using a randomized controlled trial design, 60 nurses were randomly assigned to the stimulating or sedating music or rest groups for 30min. Participants' psychoneuroimmunological parameters were measured using enzyme-linked immunosorbent assays. General estimating equation was used to analyse data. Results revealed that IL-6, TNF- and IL-10 were not detectable in this population. No significance differences in heart rate were found among the three groups. However, the stimulating music group had significantly higher mean arterial pressure levels than the sedating music group but no differences between the quiet rest group and the sedating music group. Music with different tempi had little effect on mean arterial pressure. Any effect of music on immune markers of stress requires further research. Copyright (c) 2012 John Wiley & Sons, Ltd.