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Browsing by Author "Gopal, M"

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    Synthesis and biological evaluation of novel angularly fused polycyclic coumarins
    (2005-08-01)
    Khan, IA
    ;
    Kulkarni, MV
    ;
    Gopal, M
    ;
    Shahabuddin, MS
    ;
    Sun, CM
    In a three-step sequence, an array of angularly fused polycyclic heterocycles with coumarin, benzofuran and pyridine rings were synthesized from 4-bromomethylcoumarins and salicylonitrile. All the final compounds were fully characterized and screened for anti-microbial, anti-inflammatory and analgesic activities. Several compounds exhibited promising inflammation inhibiting and anti-microbial properties. (c) 2005 Elsevier Ltd. All rights reserved.