Browsing by Author "Guo, Jia-Jiun"

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A Novel Handheld Diffuse Optical Spectroscopy System Implementation Based on High-Accuracy Multidimensional Imaging Reconstruction Model for Human Breast Healthcare Applications
(2019-01-01)
Guo, Jia-Jiun
;
Wu, Wen-Jun
;
Fang, Wai-Chi
;
電子工程學系及電子研究所
;
Department of Electronics Engineering and Institute of Electronics
Diffuse Optical Tomography (DOT) is a relatively novel, nonionizing and noninvasive technique for breast tumor imaging. Due to the diffusive nature of light propagation, the inverse problem is highly ill-posed. In this study, we propose the modified Beer-Lambert's law that reduces the number of unknown values to reduce the ill-posedness issue. An integrated mobile DOT system is proposed. The system comprises a front-end circuit and an integrated digital signal processor. The sources and the detectors are distributed hexagonal geometry for increasing the spatial resolution. The processor included the front-end controller, the iteration algorithm engine and wireless communication controller were implemented on FPGA. The functionalities of the proposed system were validated using a breast phantom. Extensive experimental results illustrated to show the performance of the proposed system. The depth of the tumor detected by the system is 20mm.
A Portable Three-Dimensional Image Reconstruction System for Breast Tumor Detection
(2018-01-01)
Wu, Wen-Jun
;
Guo, Jia-Jiun
;
Fang, Wai-Chi
;
電子工程學系及電子研究所
;
Department of Electronics Engineering and Institute of Electronics
Diffuse Optical Tomography (DOT) is a recent novel and non-invasive technology for medical imagery using near infrared light. The principle is based on the assessments of spatial variation in terms of light absorption and scattering coefficients that can be used to detect foreign bodies and tumors inside the human tissues. A previous study demonstrates a successfully reconstructed three-dimensional(3-D) image for breast tumor detection in software. Thus, the work within this study has been implemented on an integrated mobile DOT system which comprises a light sensors array front-end circuit, an analog to digital converter, a Bluetooth wireless communication module to send the results to the GUI interface on a remote displaying device. The functionalities of the proposed system were validated using an experimental static human breast phantom. The experimental results show that the proposed system can detect a tumor of the size of 0.445cm(2) at a depth of 20mm from the surface of the skin.
A Real-Time Three-Dimensional Diffuse Optical Tomography System for Breast Tumor Detection
(2018-01-01)
Wu, Wen-Jun
;
Guo, Jia-Jiun
;
Fang, Wai-Chi
;
電子工程學系及電子研究所
;
Department of Electronics Engineering and Institute of Electronics
Diffuse Optical Tomography (DOT) is a recent novel and non-invasive technology for medical imagery using near infrared light. The principle is based on the assessments of spatial variation in terms of light absorption and scattering coefficients that can be used to detect foreign bodies and tumors inside the human tissues. However, the current DOT technology is limited to a two-dimensional image reconstruction. In this paper, we propose an innovative three-dimensional nonlinear reconstruction algorithm to improve spatial and temporal resolutions. This algorithm has been implemented on an integrated mobile DOT system which comprises a light sensors array front-end circuit, an analog to digital converter, a Bluetooth wireless communication module to send the results to the GUI interface on a remote displaying device. The functionalities of the proposed system were verified using an experimental static human breast phantom. The experimental results show that the proposed system can detect a tumor of the size of 0.445cm(2) at a depth of 2cm from the surface of the skin.