Browsing by Author "Hsieh, Yu-Ling"

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Thermopneumatic suction integrated microfluidic blood analysis system
(2019-03-07)
Yang, Chiao-Hsun
;
Hsieh, Yu-Ling
;
Tsou, Ping-Hsien
;
Li, Bor-Ran
;
交大名義發表
Blood tests provide crucial diagnostic information regarding several diseases. A key factor that affects the precision and accuracy of blood tests is the interference of red blood cells; however, the conventional methods of blood separation are often complicated and time consuming. In this study, we devised a simple but high-efficiency blood separation system on a self-strained microfluidic device that separates 99.7 +/- 0.3% of the plasma in only 6 min. Parameters, such as flow rate, design of the filter trench, and the relative positions of the filter trench and channel, were optimized through microscopic monitoring. Moreover, this air difference-driven device uses a cost-effective and easy-to-use heater device that creates a low-pressure environment in the microchannel within minutes. With the aforementioned advantages, this blood separation device could be another platform choice for point-of-care testing.