Browsing by Author "Hsu, Yun"

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Acyl and Silyl Group Effects in Reactivity-Based One-Pot Glycosylation: Synthesis of Embryonic Stem Cell Surface Carbohydrates Lc(4) and IV(2)Fuc-Lc(4)
(2012-03-14)
Hsu, Yun
;
Lu, Xin-An
;
Zulueta, Medel Manuel L.
;
Tsai, Chih-Ming
;
Lin, Kuo-I
Relative reactivity evaluations showed the graded arming of toluenyl thioglucosides by variously positioned silyl groups but not by their acyl counterparts. These findings were applied in reactivity-based one-pot assembly of linker-attached Lc(4) and IV(2)Fuc-Lc(4), which are components of human embryonic stem cell surface. The sugar-galectin-1 binding was also examined.