Browsing by Author "Huang, Hsiao-Wen"

Now showing 1 - 3 of 3

Applying Fuzzy AHP to Study the KSFs of Information Security Management
(2011-01-01)
Wang, Jen-Sheng
;
Liu, Che-Hung
;
Shyu, Joseph Z.
;
Huang, Hsiao-Wen
;
交大名義發表
The launch of the digital era has made information security management a most significant and critical issue. However, perfect information security management requires certain factors for complete success. This study aims to collect Key Success Factors (KSFs) for information security management through literature review and design of a questionnaire survey. This comprises four major aspects: (1) External dimension, (2) Internal dimension, (3) Technology dimension, and (4) Execution dimension. Based on these, we proceed with categorization and analysis using Fuzzy Analytic Hierarchy Process (Fuzzy AHP or FAHP), which was applied to this study to overcome the seeming failure of general Analytical Hierarchy Process (AHP) in dealing with respondents' impersonal differences in paired comparison. The ordered ranking of objectives under each aspect is: system, human resource, security function, organization, performance, operation, market, and legislation. The results sifted from the FAHP approach suggest five top key success factors: "Training Plan", "MIS Staffing", "System Structure", "Regulation", and "Maintain Service".
Applying Fuzzy AHP to Study the KSFs of Information Security Management
(2011-01-01)
Wang, Jen-Sheng
;
Liu, Che-Hung
;
Shyu, Joseph Z.
;
Huang, Hsiao-Wen
;
科技管理研究所
The launch of the digital era has made information security management a most significant and critical issue. However, perfect information security management requires certain factors for complete success. This study aims to collect Key Success Factors (KSFs) for information security management through literature review and design of a questionnaire survey. This comprises four major aspects: (1) External dimension, (2) Internal dimension, (3) Technology dimension, and (4) Execution dimension. Based on these, we proceed with categorization and analysis using Fuzzy Analytic Hierarchy Process (Fuzzy AHP or FAHP), which was applied to this study to overcome the seeming failure of general Analytical Hierarchy Process (AHP) in dealing with respondents' impersonal differences in paired comparison. The ordered ranking of objectives under each aspect is: system, human resource, security function, organization, performance, operation, market, and legislation. The results sifted from the FAHP approach suggest five top key success factors: "Training Plan", "MIS Staffing", "System Structure", "Regulation", and "Maintain Service".
Extension of C-elegans lifespan using the center dot NO-delivery dinitrosyl iron complexes
(2018-07-01)
Huang, Hsiao-Wen
;
Lin, Yen-Hung
;
Lin, Min-Hsuan
;
Huang, Ya-Rong
;
Chou, Chih-Hung
The ubiquitous and emerging physiology function of endogenous nitric oxide in vascular, myocardial, immune, and neuronal systems prompts chemists to develop a prodrug for the controlled delivery of center dot NO in vivo and for the translational biomedical application. Inspired by the discovery of natural [Fe(NO)(2)] motif, herein, we develop the synthetic dinitrosyl iron complexes (DNICs) [Fe-2(mu-SR)(2)(NO)(4)] (1) as a universal platform for the O-2-triggered release of center dot NO, for the regulation of center dot NO-release kinetics (half-life = 0.6-27.4 h), and for the activation of physiological function of center dot NO. Using C. elegans as a model organism, the center dot NO-delivery DNIC 1 regulates IIS signaling pathway, AMPK signaling pathway, and mitochondrial function pathway to extend the lifespan and to delay the aging process based on the lifespan analysis, SA-beta gal activity assay, and next-generation RNA sequencing analysis. This study unveils the anti-aging effect of center dot NO and develops DNICs as a chemical biology probe for the continued discovery of unprecedented NO physiology. [GRAPHICS] .