Browsing by Author "Ku, Meng-Yen"

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Dynamic manipulation and patterning of microparticles and cells by using TiOPc-based optoelectronic dielectrophoresis
(2010-06-15)
Yang, Shih-Mo
;
Yu, Tung-Ming
;
Huang, Hang-Ping
;
Ku, Meng-Yen
;
Hsu, Long
We develop light-driven optoelectronic tweezers based on the organic photoconductive material titanium oxide phthalocyanine. These tweezers function based on negative dielectrophoresis (nDEP). The dynamic manipulation of a single microparticle and cell patterning are demonstrated by using this light-driven optoelectronic DEP chip. The adaptive light patterns that drive the optoelectronic DEP onchip are designed by using Flash software to approach appropriate dynamic manipulation. This is also the first reported demonstration, to the best of our knowledge, for successfully patterning such delicate cells from human hepatocellular liver carcinoma cell line HepG2 by using any optoelectronic tweezers. (C) 2010 Optical Society of America
Light-driven manipulation of picobubbles on a titanium oxide phthalocyanine-based optoelectronic chip
(2011-04-11)
Yang, Shih-Mo
;
Yu, Tung-Ming
;
Huang, Hang-Ping
;
Ku, Meng-Yen
;
Tseng, Sheng-Yang
Microbubbles have a variety of applications in science and biological technology. Here, we demonstrate the manipulation of the picoliter gas bubble (picobubble) based on the optoelectronic-mechanism. The organic photoconductive material, titanium oxide phthalocyanine (TiOPc), was developed to make the light-sensitive substrate of this optoelectronic chip. The virtual electrodes are formed by projecting the dynamic light pattern onto TiOPc layer for generating the desired nonuniform electric field. The picobubble suspended in silicone oil can be manipulated with the velocity of 40-50 mu m/s. The driving force up to 160 pico-Newtons could be generated for manipulating a gas bubble of 300 picoliters. (C) 2011 American Institute of Physics. [doi:10.1063/1.3580760]
ORGANIC PHOTOCONDUCTIVE DIELECTROPHORESIS BY USING TITANIUM OXIDE PHTHALOCYANINE FOR MICRO-PARTICLES MANUPULATION
(2010)
Yu, Tung-Ming
;
Yang, Shi-Mo
;
Huang, Hang-Ping
;
Ku, Meng-Yen
;
Tseng, Sheng-Yang
This paper reports our updating development for the organic photoconductive dielectrophoresis (OPDEP) by using titanium oxide phthalocyanine (TiOPc) material for the manipulation of micro-objects. The advantages of organic photoconductive material include non-toxicity, low cost, easy coating fabrication, flexibility, panchromaticity and high photosensitivity [1]. TiOPc has the high photoconductivity and the optical absorptions in the near infrared region (550 - 850 nm) to be a candidate of the light-sensitive charge generation layer. OPDEP chip is easily mass-produced by using a spin-coating process. Here, we demonstrate two kinds of the manipulations of micro-particles on our OPDEP chip. Firstly, the trapping and movement of single micro-particle is achieved by the ring shaped virtual electrode. Secondly, the steel rim shaped virtual electrode is designed to rotate micro-particles and characterize the OPDEP induced force.