Browsing by Author "Lee, Ya-Wei"

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Effect of different gold nanoparticle sizes to build an electrical detection DNA between nanogap electrodes
(2007-05-01)
Chang, Tien-Li
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Lee, Ya-Wei
;
Chen, Chun-Chi
;
Ko, Fu-Hsiang
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材料科學與工程學系奈米科技碩博班
An experimental study for identifying DNA strands immobilized in the different particle sizes of gold nanoparticle (AuNP) between nanogap electrodes is presented. The nanogap-based electrics chip demonstrates a significant electrical property with a target DNA (DNA) concentration of 10 pM in the different particle sizes of AuNP to be analyzed in order to make the assay useful for an integrated lab-on-a-chip application system. The biochips with nanogap electrodes are fabricated by e-beam lithography (EBL). Different from traditional detection methods including polymerase chain reaction (PCR) based on assays which are expensive and time consuming for DNA strands research. By the method of electrical characterization, a change in measured current through the different particle sizes of AuNP can pave the way for further use in sensitive biomolecule detection study. (c) 2007 Published by Elsevier B.V.
Experimental and theoretical analysis of microjet droplet behavior
(2007-05-01)
Lee, Ya-Wei
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Chang, Tien-Li
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Ko, Fu-Hsiang
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Chang, Shuo-Hung
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Chen, Chun-Chi
A model for predicting fluid flow with forming droplet in a microjet fluidic device is described. The model considers the approach of non-linear autoregressive moving average model with exogenous inputs (NARMAX) to analyze the dynamic flow behavior of droplet that can be helpful to design microjet geometry in bionanotechnology application. The study in microjet controls a droplet size that is arrival at nanoliter volumes. The working fluids in experimental measuring process are the solution of gold nanoparticles and oil acid. This study focuses on a real time for droplet behavior with the variety of pressure in the channel. Based on identifying both time and frequency domain models, the behavior of droplet flow could be analyzed in microfluidic on-chip system. (c) 2007 Published by Elsevier B.V.
Manipulating mimicked magnetosome chains produced Using superparamagnetic microbeads in a confined space
(2016-03-05)
Li, Yan-Hom
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Su, Ting-Yu
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Chang, Tien-Li
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Lee, Ya-Wei
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機械工程學系
In this study, we investigated the dynamics of microchains containing superparamagnetic microbeads under the influence of oscillating magnetic fields in a confined space. The behavior of constrained microchains was investigated experimentally. Chains in confined spaces were first formed using a static directional field or a permanent magnet and then manipulated using an additional dynamical perpendicular field. An oscillating chain in a confined space can be designed to mimic magnetosome chains synthesized by magnetotactic bacteria, which have been exploited recently for various applications in biological and medical sciences. The effects of crucial parameters, such as the lengths of particle chains and sizes of confined spaces, were thoroughly analyzed to observe the distinct behavior and investigate the dynamics of the constrained chains. (C) 2016 Elsevier B.V. All rights reserved.
Use of electromagnetic induced flow fluctuations in a nanofluidic-assisted cooling device
(2015-01-01)
Su, Jen-Pao
;
Wu, Jong-Shinn
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Lee, Ya-Wei
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機械工程學系
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Department of Mechanical Engineering
In this study, an electromagnetically controlled cooling device (ECCD) is proposed, employing magnetic nanofluid (MNF) and electromagnetohydrodynamics to ameliorate the waste-heat dissipation of mechatronic systems. The MNF was charged in a condenser chamber as an auxiliary coolant, and was prepared from fine ferromagnetic particles of iron ferrite by using a chemical coprecipitation technique. A radial basis function neural network-based training model was employed for examining the electromagnetic resonance of the ECCD at a wide heating range. Satisfactory agreement between the experimental and predicted results indicated the accuracy of the model in capturing the ECCD dynamics. The nonlinearity of ECCD dynamics were also identified as a feature of frequency resonance by mapping a discrete-time model into generalized frequency response functions (GFRFs). Accordingly, the effect of electromagnetic induction relating to ECCD performance can be further confirmed.