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Browsing by Author "Liu, Jyun-Cheng"

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    Tumor targeting with DGEA peptide ligands: a new aromatic peptide amphiphile for imaging cancers
    (2019-01-25)
    Zhan, Fu-Kai
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    Liu, Jyun-Cheng
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    Cheng, Bill
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    Liu, Yen-Chu
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    Lai, Tsung-Sheng
    We report a novel fluorescent bioprobe, tetraphenylethylene-Phe-Asp-Gly-Glu-Ala (TPE-FDGEA), and its self-assembly behavior, photophysical properties, and biocompatibility. The hydrogelator TPE-FDGEA exhibited aggregation-induced emission characteristics, which facilitated imaging of PC-3 human prostate cancer cells, thereby demonstrating the utility of such fluorescent probes for specific labeling of target cells in vitro.