Browsing by Author "Liu Chih-Yueh"

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ALPHA-SELECTIVE GLYCOSYLATION METHOD
(2013-06-20)
Mong Kwok-Kong Tony
;
Chao Chin-Sheng
;
Lu Shao-Ru
;
Liu Chih-Yueh
The present invention provides an α-selective glycosylation method. The α-selective glycosylation method includes performing a reaction of a donor having a saccharide structure and a formamide-containing compound to form a glycosyl imidate compound; and in one pot environment, performing an addition reaction of the glycosyl imidate compound and an acceptor having a hydroxyl group to form an α-glycoside with high α-selectivity. The α-selective glycosylation method is applicable to the large scale production and easy to recover the formamide-containing compound.