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Browsing by Author "Shih, Wei-Chin"

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    Nickel promoted switchable hydroheteroarylation of cyclodienes via C-H bond activation of heteroarenes
    (2015-07-01)
    Lee, Wei-Chih
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    Shih, Wei-Chin
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    Wang, Ting-Hsuan
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    Liu, Yuhua
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    Yap, Glenn P. A.
    We demonstrated Ni-catalyzed switchable hydroheteroarylation of cyclic dienes via C-H bond activation of heteroarenes. In the presence of an N-heterocyclic carbene (NHC) ligand, hydroheteroarylation of cyclic diene with azole afforded alpha-alkenyl-azole, forging a Heck-like product without using any external oxidant. Conversely, changing the ligand to PCy3 would switch this reaction manifold to afford the other isomeric beta-alkenyl substituted azole. (C) 2015 Elsevier Ltd. All rights reserved.