Browsing by Author "Wallace, Steve"

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Culture and the importance of usability attributes
(2013-01-01)
Wallace, Steve
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Reid, Adrian
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Clinciu, Daniel
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Kang, Jin-Su
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經營管理研究所
Purpose - This study into cultural usability aims to identify whether the importance of usability attributes varied between nationalities, and whether this variance was related to cultural dimensions. Design/methodology/approach - A total of 144 subjects from four countries were surveyed on the importance they placed on the usability attributes of cell phones. Results were compared by country, and relationships with cultural dimensions were investigated. Findings - For each country, usability attributes were not rated equally. Across countries, no difference in the rating of effectiveness was found, while ratings of efficiency and satisfaction varied significantly. In addition, the study identified significant relationships between the importance given to efficiency and satisfaction and cultural dimensions identified by Hofstede and the World Values Survey, with values relating to task-orientation influencing efficiency, and non-task oriented values affecting the. importance users place on satisfaction. Practical implications - Product designers and usability practitioners need to consider these cultural differences when designing products and when evaluating, measuring, and making recommendations on product usability Originality/value - Previous studies in this area have shown the existence of differences in preference for usability attributes based on nationality No studies known to the authors have connected this to cultural dimensions. Understanding of this connection supports usability practitioners in their work not just in specific countries but also in cultural regions. It also allows the more precise modeling by researchers of culture's interaction with usability.
The Relevance of Protein-Ligand Interaction Profiles in Computer-Aided Novel Compound Design and Applications
(2011-09-01)
Clinciu, Daniel L.
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Yang, Jinn-Moon
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Hsu, Kai-Cheng
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Lo, Chi-Chun
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Wallace, Steve
Advancements in methods and tools used in the solving of crystal structures account for the continuously increasing number of compounds available in databases. Various methods and tools are employed in current bioinformatics to screen, retrieve and analyze lead compounds from databases for drug design and industrial use, bringing marked advantages in terms of reducing the time and cost of studies. However, a pivotal point in lead compounds retrieval is the proper understanding and representation of their binding interactions. In this review we compare current methods used in virtual screening and post screening analysis of lead compounds which employ interaction profiles as a key feature. We also emphasize the use of such methods in mining novel compounds for manufacturing nutritional supplements, cosmetics and other industrial products.