Browsing by Author "Wu, Pei-Chen"

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A DUAL-EDGED TRIGGERED EXPLICIT-PULSED LEVEL CONVERTING FLIP-FLOP WITH A WIDE OPERATION RANGE
(2013-01-01)
Chen, Mei-Wei
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Chang, Ming-Hung
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Wu, Pei-Chen
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Kuo, Yi-Ping
;
Yang, Chun-Lin
In a multiple supply voltage system, the level converters are inserted between two different voltage domains. However, those level converters may cause the propagation delays and power consumption. In order to eliminate the overhead of level conversion, a dual-edged triggered explicitpulsed level converting flip-flop (DETEP-LCFF) with a wide operation range is proposed. It is composed of a clock pulse generator and a modified differential cascode voltage switch with pass gate (DCVSPG) latch. The clock pulse generator has the symmetric pulse triggering time and holding period helping shorten the D-Q delay. By employed diode-connected PMOS transistors and two NMOS transistor stacked below the diode PMOS transistors, the proposed DETEP-LCFF can be operated from near-threshold region to superthreshold region. It is implemented in TSMC 65nm CMOS technology. It functions correctly across all process corners with a wide input voltage range, from 400mV to 1V. The proposed LCFF has a minimum D-Q delay of 781 ps, a setup time of 610ps, and a power dissipation of 2.3 mu W when the input voltage is OAV.
Multi-Layer Adaptive Power Management Architecture for TSV 3DIC Applications
(2013)
Chang, Ming-Hung
;
Hsieh, Wei-Chih
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Wu, Pei-Chen
;
Chuang, Ching-Te
;
Chen, Kuan-Neng
In this work, a multi-layer hierarchical distributed power delivery architecture for TSV 3DIC is proposed. By decoupling global and local power networks, the proposed power delivery architecture can be flexibly configured for different power requests. The decoupled power architectures can also greatly reduce the required decoupling capacitor sizes for voltage stabilization. Meanwhile, a multi-threshold CMOS switched capacitor DC-DC converter with up to 78% power efficiency is implemented in 65nm CMOS for hierarchical distributed power delivery architecture. An adaptive power management technique is presented to work in the local power network to increase the power efficiency. The proposed multi-layer hierarchical distributed power delivery architecture is also very useful for the heterogeneous integration in 3DIC chips.
Near-/Sub-V-th Process, Voltage, and Temperature (PVT) Sensors with Dynamic Voltage Selection
(2013)
Chang, Ming-Hung
;
Lin, Shang-Yuan
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Wu, Pei-Chen
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Zakoretska, Olesya
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Chuang, Ching-Te
A process, voltage and temperature (PVT) sensors with dynamic voltage selection are proposed for environmental management in the ultra-low voltage dynamic voltage and frequency scaling (DVFS) system. The process and voltage (PV) sensors initially monitor the process variation. With known process information, PV sensors can real-time provide voltage variation status. The temperature sensor has six temperature sensitive ring oscillators (TSROs) generating frequency proportional to temperature. It dynamically selects the proper TSRO to convert the frequency into digital readings according to voltage status provided by PV sensors. With known process and voltage information from PV sensors, a pure temperature measurement result can be obtained. The proposed PVT sensors are designed in TSMC 65nm CMOS technology. This work can be dynamically operated over an ultra-low voltage range from 0.25V to 0.5V. Only 2.3 mu W is consumed at 0.25V. They can achieve 0.15 degrees C resolution and 50k samples/sec conversion rate.
The role of indoxyl sulfate in renal anemia in patients with chronic kidney disease
(2017-10-10)
Wu, Chih-Jen
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Chen, Cheng-Yi
;
Lai, Thung-S.
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Wu, Pei-Chen
;
Chuang, Chih-Kuang
Renal anemia is a common complication in patients with advanced chronic kidney disease. In vitro studies have shown that indoxyl sulfate decreases erythropoietin production. Whether this effect is seen in vivo remains unclear. Our goal was to explore the role of indoxyl sulfate in renal anemia. We found serum indoxyl sulfate levels are significantly and negatively associated with erythropoietin levels in human. A multiple stepwise linear regression analyses after adjustment for other independent parameters revealed that free indoxyl sulfate, and total indoxyl sulfate were significantly associated with erythropoietin levels. In animal studies, erythropoietin gene and protein expression were markedly inhibited in rats with chronic kidney disease; however, this effect was significantly reversed by lowering serum indoxyl sulfate with AST-120. Indoxyl sulfate may also inhibit erythropoietin expression in animal models with chronic kidney disease. These findings further support the role of indoxyl sulfate in the development of renal anemia.
Uncertainty analysis for measurement of measurand
(2010-11-01)
Chen, Hung-Chia
;
Wu, Pei-Chen
;
Huang, Jing-Ye
;
Chen, Lin-An
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統計學研究所
For measuring the true value of a measurand, vague statistical concept of measurand results in inefficient uncertainty analysis of measurement. The vagueness is caused by the fact that true value of the measurand is an unknown parameter such as population mean or median and the measurement of this true value is a random variable. Generally a parameter may be estimated remarkably more efficiently than the prediction of the random variable. The classical uncertainty analysis in the literature has been developed based on the structure that a measurand is a random variable. This misspecification of statistical concept costs serious price of sacrificing efficiency in terms of length of the uncertainty interval. The purpose of present study is to formally formulate a statistical model for the true value of measurand and provide an uncertainty analysis for the measurement of this true value. (C) 2010 Elsevier Ltd. All rights reserved.