Browsing by Author "Wu, Shun-De"

Now showing 1 - 3 of 3

Analyze fluorescent characteristic of cancer cell using hyperspectroscopic imaging system (HIS)
(2012-01-01)
Hsieh, Yao-Fang
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Chen, Chih-Hsien
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Mang, Ou-Yang
;
Duann, Jeng-Ren
;
Chiou, Jin-Chern
Currently, the cancer was examined by diagnosing the pathological changes of tumor. If the examination of cancer can diagnose the tumor before the cell occur the pathological changes, the cure rate of cancer will increase. This research develops a human-machine interface for hyper-spectral microscope. The hyper-spectral microscope can scan the specific area of cell and records the data of spectrum and intensity. These data is helpful to diagnose tumor. This study finds the hyper-spectral imaging have two higher intensity points at 550nm and 700nm, and one lower point at 640nm between the two higher points. For analyzing the hyper-spectral imaging, the intensity at the 550nm peak divided by the intensity at 700nm peak. Finally, we determine the accuracy of detection by Gaussian distribution. The accuracy of detecting normal cells achieves 89%, and the accuracy of cancer cells achieves 81%.
Portable noninvasive system for oral cancer diagnosis
(2012)
Yang, Chin-Siang
;
Ou-Yang, Mang
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Hsieh, Yao-Fang
;
Chen, Yu-Ta
;
Chiou, Jin-Chern
This study presents a portable noninvasive detection system which can get the image of specific spectral immediately, that promote to oral cancer diagnosis. According to research literature show the performance called autofluorescence of cells after exciting by specific wave band of light. It is different of the spectrum distribution for lesions of epithelial cells and normal cells after fluorescence excite, that is a basis of diagnosing to oral cancer. The convenient equipment for detection of oral cancer is modified for existing handheld microscope. From Fig. 1, the UV LED illuminates to the surface of object and excites the cells which produce fluorescent reaction and showed the image with specific wavelength. The image passes through the central channel and filter out unwanted spectral by the selection of filter, and focused by the focus lens on the image sensor, therefore we can achieve the specific wavelength image via fluorescence reaction.
The new hyperspectral microscopic system for cancer diagnosis
(2011-01-01)
Hsieh, Yao-Fang
;
Mang, Ou-Yang
;
Chiou, Jin-Chern
;
Lin, Yung-Jiun
;
Tsai, Ming-Hsui
Until now, the cancer was examined by diagnosing the pathological changes of tumor. If the examination of cancer can diagnose the tumor before the cell occur the pathological changes, the cure rate of cancer will increase. This research develops a human-machine interface for hyper-spectral microscope. The hyper-spectral microscope can scan the specific area of cell and records the data of spectrum and intensity. These data is helpful to diagnose tumor. This research aims to develop a new system and a human-machine interface to control the hyper-spectral microscope. The interface can control the moving speed of motor, the exposure-time of hyper-spectrum, real-time focus, image of fluorescence, and record the data of spectral intensity and position.