Browsing by Author "Zhang, Bo"
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Item type:Item, Compensation for I/Q Imbalances and Bias Deviation of the Mach-Zehnder Modulators in Direct-Detected Optical OFDM Systems(2009-01-01) ;Peng, Wei-Ren ;Zhang, Bo ;Wu, Xiaoxia ;Feng, Kai-MingWillner, Alan E.We demonstrate an equalization technique to simultaneously compensate for the fiber chromatic dispersion and the distortions induced by the in-phase/quadrature-phase (I/Q) imbalances and bias deviation in the Mach-Zehnder modulators (MZMs). With this technique, the requirement for the monitoring circuits at the transmitter could be relaxed or even eliminated, and thus simplifies the system design and reduces the system cost. The system exhibits a good performance with our proposal over a broad range of imbalances and bias deviation in the MZM. With deliberately introducing I/Q imbalances and bias deviation, we have observed a 2- and 4-dB optical signal-to-noise ratio improvement, for the back-to-back and 800 km of uncompensated standard single-mode fiber transmission, respectively, with our proposed scheme.Item type:Item, Experimental Demonstration of 1600 km SSMF Transmission of a Generalized Direct Detection Optical Virtual SSB-OFDM System(2008-01-01) ;Peng, Wei-Ren ;Zhang, Bo ;Wu, XiaoXia ;Feng, Kai-MingWillner, Alan E.We experimentally demonstrate a generalized VSSB-OFDM format that judiciously determines the frequency gap between an inserted RF tone and the signal. The proposed scheme for 10 Gbps exhibits similar to 3 dB penalty after 1600 km SSMF transmission, and has an 8 dB improvement over the regular VSSB-OFDM.Item type:Item, Genome mining and biosynthesis of kitacinnamycins as a STING activator(2019-05-14) ;Shi, Jing ;Liu, Cheng Li ;Zhang, Bo ;Guo, Wen JieZhu, JiapengCinnamoyl-containing nonribosomal peptides (CCNPs) are a small group of secondary metabolites with potent biological activities produced by actinobacteria. Two remarkable features in the biosynthesis of CCNPs include the nonribosomal peptide synthases (NRPSs) for assembly of the depsipeptide backbone and the type II polyketide synthases (PKSs) for N-terminal cinnamoyl moiety construction. Here, we present a genome mining approach targeting both NRPS and type II PKS for discovery of new CCNPs, which led to the identification of 51 putative CCNP gene clusters from public bacterial genome databases. After strain prioritization, a novel class of CCNP-type glycopeptides named kitacinnamycins, one of which showing potent activation ability towards the stimulator of interferon genes (STING) protein, was identified. Bioinformatic, genetic and biochemical analysis revealed the use of the NRPS assembly line to form the macrocyclic peptide backbone, followed by a P450 monooxygenase to generate terminal oxidized groups. A glycosyltransferase with relatively broad substrate specificity transfers sugars to the newly generated OH/COOH group. The protein crystallographic study further provided structural insights into this glycosylation. Our results not only demonstrated the feasibility of genome mining and strain prioritization for the discovery of new bioactive natural products but also disclosed the biosynthetic pathway for kitacinnamycins.Item type:Item, Spectrally Efficient Direct-Detected OFDM Transmission Incorporating a Tunable Frequency Gap and an Iterative Detection Techniques(2009-12-15) ;Peng, Wei-Ren ;Zhang, Bo ;Feng, Kai-Ming ;Wu, XiaoxiaWillner, Alan E.We analytically and experimentally demonstrate a linearly field-modulated, direct-detected virtual single-side-band orthogonal frequency-division multiplexing (VSSB-OFDM) system that employs a tunable frequency gap and an iterative detection technique. The VSSB-OFDM that uses no frequency gap, which is referred to as the gapless VSSB-OFDM, is proposed as a spectrally efficient format. Compared with the intensity-modulated SSB-OFDM, the gapless VSSB-OFDM saves half the electrical bandwidth (BW), and exhibits better receiving sensitivity and more robust tolerance against fiber chromatic dispersion (CD). Furthermore, by incorporating a tunable frequency gap between the optical carrier and the OFDM data sideband, the calculating burden of the iterative detection is greatly alleviated and the system performance can be flexibly improved within moderate iterations. The width of the optimum frequency gap is found to be similar to 0.35 sideband BW, which is reached by trading the levels of signal-signal beat interference and the residual image beat interference. Such a gapped VSSB-OFDM system requires fewer iterations to extract the desired data from the interfered signal and exhibits greater robustness against the carrier-to-signal-power ratio (CSPR) variation, compared with the gapless VSSB-OFDM. In this paper, the analytical model of the proposed gapped VSSB-OFDM system will be addressed. In addition, we also successfully conduct a gapped VSSB-OFDM signal transmission over 1600 km of uncompensated standard single-mode fiber (SSMF) with only similar to 3 dB optical SNR (OSNR) penalty, and obtain a significant OSNR sensitivity improvement of 8 dB, compared with the gapless VSSB-OFDM, after such a 1600-km fiber link.