Browsing by Author "Tai, Yu-Ting"

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A CMOS-Based Phototransistor for High-Sensitivity Biochemical Detection Using Absorption Photometry
(2008)
Chang, Yu-Wei
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Tai, Yu-Ting
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Huang, Yang-Tung
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Yang, Yuh-Shyong
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電子工程學系及電子研究所
This paper proposes a high-sensitivity biosensing system on the basis of absorption photometry and a phototransistor. Manufactured in a standard 0.35-mu m CMOS technology, the phototransistor exhibits a responsivity higher than 1000 A/W for 650-nm light. The TMB/H(2)O(2)/HRP method is chosen as a useful platform to determine the amount of various interesting targets. For the biochemical detection, a sample volume of only 10 mu l is required to be dropped on the slide above the phototransistor. Experimental results demonstrate that a high sensitivity of 2.5 mu A/pM is achieved, and the minimum HRP concentration successfully detected is 2.7 pM. This detection limit is three orders of magnitude better than that of a reported silicon biosensor.
A High-Sensitivity CMOS-Compatible Immunosensor Based on the HRP/TMB/Streptavidin System
(2008)
Tai, Yu-Ting
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Chang, Yu-Wei
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Lin, Ming-Yu
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Yang, Yuh-Shyong
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Huang, Yang-Tung
In this report, a CMOS-compatible colorimetric biosensor based on HRP/TMB/streptavidin system is proposed. HRP activity is used for labelled target quantification by photometric detector. The modulation of light intensity due to enzyme reaction can easily be detected in 96-well microarray plate by providing 650nm light source (LED). There is good correlation between absorbance in 650nm and the concentration of HRP-streptavidin with detection limit in 1.33 pM. This device is reusable and suits for various targets by microarray plate modification rather than biochip. With the advantage of portable, low cost, and reusable, this new designed immunosensor could be widely used for both research and diagnostic purposes.
A Phototransistor-Based High-Sensitivity Biosensing System Using 650-nm Light
(2009-05-01)
Chang, Yu-Wei
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Tai, Yu-Ting
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Huang, Yang-Tung
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Yang, Yuh-Shyong
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生物科技學系
A miniature optical biosensing system based on a PMOS phototransistor and absorption photometry is proposed. The phototransistor was manufactured in a standard 0.35-mu m CMOS process, and it exhibited a responsivity higher than 1000 A/W for 650-nm light. For biochemical applications, the TMB/H(2)O(2)/HRP method was adopted as a useful basis in our system. A sample volume of only 10 mu l was required to be dropped on the slide above the phototransistor. Experimental results demonstrated that a high sensitivity of 2.5 mu A/pM was achieved, and the minimum HRP concentration successfully detected was 2.7 pM. This detection limit is three orders of magnitude better than that of a lately reported silicon biosensor, and is even comparable to that of a commercial spectrophotometer.
Accessing Manufacturing Yield for Gamma Wafer Sawing Processes in COG Packaging
(2011-08-01)
Pearn, Wen-Lea
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Tai, Yu-Ting
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Huang, Kai-Bin
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Ku, Pin-Lun
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工業工程與管理學系
The technology of thin film transistor liquid crystal display (LCD) has become more popular due to great demand for worldwide consumer electronic products. Driver integrated circuit (IC) is a critical device that is embedded sophisticated circuits to drive panels. Since narrow border design on display products is current trend, dimensions of driver ICs are shrunken. In the high-density LCD driver ICs, the operation of wafer sawing is essential and needs accurate yield assessment. However, inevitable process variance changes could arise from sawing machine, material, operation, and workmanship, and may not be detected within short time. Conventionally, manufacturing yield is evaluated applying typical yield measure index method under the assumptions that the processes are stable and normal. To assess manufacturing yield for Gamma wafer sawing processes more accurately, we present a modified yield measure index method. Using the proposed method, the magnitudes of the undetected variance change, which are functions of the detection power of the S(2) chart, are incorporated into the evaluation of manufacturing yield. In addition, we demonstrate, mathematically, that the accommodation would not be affected by the scale parameter of Gamma distribution. For illustration purpose, a real-world case in a wafer sawing factory which is located on the Science-based Industrial Park in Hsinchu, Taiwan, is presented.
Capability Assessment for Weibull In-Cell Touch Panel Manufacturing Processes With Variance Change
(2014-05-01)
Tai, Yu-Ting
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Pearn, Wen Lea
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Huang, Kai-Bin
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Liao, Lu-Wei
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工業工程與管理學系
Since touch panels can provide natural user-interface, including fluent multipoint touch or advance gesture recognition, recently they have been extensively applied in various portable devices, such as smart phones and tablet PCs. In-cell touch panel is the highest integration touch technology as compared to the on-cell and typical touch panel manufacturing technologies for the thinnest and lightest structure. In in-cell manufacturing processes, manufacturing yield assessment is an essential issue. However, inevitable process variance changes could arise from equipment, material, and operation, and may not be detected within a short time. In addition, the process output usually has a Weibull distribution. To circumvent the undetected variance change causing the inaccurate manufacturing yield calculation, we provide a yield measure index to avoid overestimating when the underlying distribution is Weibull with variance change. We also show that the accommodation of the process capability index would not be affected by the scale parameter of Weibull distribution. Applying this method, the magnitudes of the undetected variance change are incorporated into the evaluation of manufacturing yield. For illustration purposes, a real application in an in-cell manufacturing factory, which is located in the Science-based Industrial Park in Hsinchu, Taiwan, is presented.
Statistical Approach for Cycle Time Estimation in Semiconductor Packaging Factories
(2009-07-01)
Pearn, W. L.
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Tai, Yu-Ting
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Lee, J. H.
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工業工程與管理學系
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Department of Industrial Engineering and Management
In the semiconductor industry, to enhance customer satisfactions and ability of quick responses, the development of cycle time estimation model is very important. Cycle time estimation is an essential planning basis, which has many applications, especially on the analyses of performance indexes, capacity planning, and the assignments of due dates. In this paper, we provide a statistical approach for cycle time estimation in semiconductor plastic ball grid array (PBGA) packaging factories. Due to today's fierce competitive environments in the semiconductor industry, planners involved in PBGA packaging factories need an approach to obtain estimated cycle times with different confidence to ensure the due date assignments more accurately. Therefore, upper confidence bounds of estimated cycle times at various confidence coefficients are also presented in this paper. We demonstrate the applicability of the proposed cycle time estimation model incorporating the upper confidence bounds by presenting a real-world example taken from a PBGA packaging shop floor in a semiconductor packaging factory located in the Science-Based Industrial Park in Hsinchu, Taiwan.
The development of wireless sensor network for ECG monitoring
(2006)
Lin, Jun-Liang
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Liu, Hsien-Chieh
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Tai, Yu-Ting
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Wu, Hsin-Hsien
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Hsu, Shuo-Jen
The main problem we want to solve contains two subjects: The first one is the patient's pressure due to wired physiological signal estimation. With wireless sensor network technique, patients only need to carry a few small nodes, and then the physiological signal can be transmitted in the air. The other subject of the vital problem is that some protocols, like Bluetooth, provide a peer to peer wireless communication technique, but such peer to peer network may need a complex algorithm to find the best data transmission path. In this study, we use the hierarchy routing as network topology that three-layer architecture contains PAN coordinator, router and device. The study focuses on implementation of a prototype electrocardiography (ECG) system which replaces wired connections between sensor points and a central node with wireless links. Successful implementation of the final system would be of benefit to all involved in the use of ECG as access to and movement of the patient would not be impeded by the physical constraints imposed by the cables. Most aspects of the design would also be portable to other sensor applications, making the work relevant to a vast range of systems where movement of sensors is desirable and constrained by hard-wired links.