Browsing by Issue Date, starting with "2005-03-11"
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Item type:Item, Identification of V23RalA-Ser(194) as a critical mediator for aurora-A-induced cellular motility and transformation by small pool expression screening(2005-03-11) ;Wu, JC ;Chen, TY ;Yu, CTR ;Tsai, SJHsu, JMHuman Aurora kinases have three gene family members: Aurora-A, Aurora-B, and Aurora-C. It is not yet established what the specificity of these kinases are and what signals relayed by their reactions. Therefore, we employed small pool expression screening to search for downstream substrates of Aurora-A. Interestingly, all of the identified Aurora-A substrates were resistant to serve as substrates for Aurora-B or Aurora-C, suggesting that these Aurora family members may have distinct substrate specificity for propagation of diverse signaling pathways, even though they share a conserved catalytic kinase domain. Of the candidate substrates, Aurora-A could increase the functional activity of RalA. Mutational analysis revealed that RalA-Ser(194) was the phosphorylation site for Aurora-A. Ectopic expression of V23RalA-WT could enhance collagen I-induced cell migration and anchorage-independent growth in Madin-Darby canine kidney (MDCK) Aurora-A stable cell lines. In contrast, overexpression of V23RalA-S194A in MDCK Aurora-Astable cell lines abolished the intrinsic migration and transformation abilities of Aurora-A. To our knowledge, this is the first systematic search for the downstream substrates of Aurora-A kinase. Moreover, these results support the notion that Aurora-A may act in concert with V23RalA through protein phosphorylation on Ser(194) to promote collagen I-induced cell motility and anchorage-independent growth in MDCK epithelial cells.Item type:Item, 利用控制偏振逐段曝照方法製作複雜的光纖光柵結構(2005-03-11) ;莊凱評 ;許立根 ;蔡孟璋賴杰本發明係提出一製造複雜光纖光柵曝照系統及方法,係於相位光罩製程或雙光束干涉製程中,加入一可旋轉之1/2波片以及一偏振分光稜鏡來完成,並將感光性光纖放置於相對位移可以準確控制至奈米等級之位移平台上,藉此組合可以達到任意相位和折射率變化之複雜光纖光柵結構之製作。本發明之特點在於整個曝照過程只需一次連續移動即可完成,並且在完成複雜折射率變化之控制上更為準確及穩定。Item type:Item, 一種感光性光纖之曝照系統及方法(2005-03-11) ;莊凱評 ;許立根 ;蔡孟璋賴杰本發明係提出一種僅需旋轉一旋轉反射鏡即可達微調干涉角度目的之雙光束干涉曝照系統。本發明之曝照系統將經旋轉反射鏡反射並經分光後之兩分光束中之任一組分光束之光程中置入一可旋轉之1/2波長偏振片,再將感光性光纖置放於一相對位移可準確控制至奈米等級的移動平台上,之後僅需在逐段曝照的過程中,將不同的相對位置配合旋轉偏振片於不同角度,即可達到一次連續曝照可至做出平均折射率平坦化的光纖光柵,此外,更可藉由旋轉對換1/2波長偏振片快慢軸的方式,來製作具180°相位改變之相位移光纖光柵。Item type:Item, Growth of CaF2/a-C core/shell nanowires.(2005-03-13) ;Huang, CH ;Chang, YH ;Lee, CY ;Chiu, HT應用化學系Item type:Item, Enzymatic formation of multiple triterpenes by mutation of tyrosine 510 of the oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae.(2005-03-13) ;Chang, CH ;Wu, TK ;生物科技學系Department of Biological Science and TechnologyItem type:Item, Synthetic approach to ellipticine.(2005-03-13) ;Ho, TL ;Hsieh, SY ;應用化學系Department of Applied ChemistryItem type:Item, Material and interface engineering for high-performance light-emitting diodes.(2005-03-13) ;Jen, AKY ;Niu, YH ;Liu, MS ;Yip, HKang, MSItem type:Item, 書藝結緣.伊玉桂教官以筆會友(國立陽明大學, 2005-03-15)錢玨琄去年十月間,校園內悄悄地開設了一個極小規模的書法練習班,由甫退休的伊玉桂教官帶領十餘位學員們共同切磋書法技藝。幾個月下來,參加的學員們都覺得受益匪淺.....Item type:Item, 請來品嚐熱情有勁的「僑生粥」(國立陽明大學, 2005-03-15)陽明電子報編輯小組「這不是僑生粥!這不是僑生粥!」為了宣導「僑生週」活動,由醫二的韓龍疇編導,牙二的蔡佑彬、蔡佳君及溫國耀擔綱演出了一齣短劇,爆笑內容撂倒一缸子的陽明人,也充分嶄露出陽明醫學生的聰穎與機靈Item type:Item, BIOINFO 2005國際生物資訊學術研討會(國立陽明大學, 2005-03-15)陽明電子報編輯小組<研究發展處提供>BIOINFO 2005 為一國際生物資訊學術研討會,由AASBi、InCoB 及 KSBI 聯合舉辦,並訂於 2005 年 9 月 22-24 日於韓國釜山市舉行Item type:Item, Stimulated emission and lasing of random-growth oriented ZnO nanowires(2005-03-15) ;Hsu, HC ;Wu, CY ;Hsieh, WF ;光電工程學系Department of PhotonicsWe report room-temperature ultraviolet stimulated emission and lasing from optically pumped high-quality ZnO nanowires. Emission due to the exciton-exciton scattering process shows apparent stimulated-emission behavior. Several sharp peaks associated with random laser action are seen under high pumping intensity. The mechanism of laser emission is attributed to coherent multiple scattering among the random-growth oriented nanowires. The characteristic cavity length is determined by the Fourier transform of the lasing spectrum. (C) 2005 American Institute of Physics.Item type:Item, Item type:Item, 西非照片集錦 (一)(國立陽明大學, 2005-03-15)陽明電子報編輯小組記錄時間:2005 / 01 / 23 至 2005 / 01 / 26 從沒想過自己有機會能飛到地球的另一端。布吉納法索,一個台灣7倍大的國家,位於西非內陸,人民發展指數(human development index)世界倒數第三。政局穩定、人民勤奮,卻因無大河、無鉅礦、天少雨、地貧瘠等先天條件不良而赤貧Item type:Item, 醫學院李院長參訪之行(國立陽明大學, 2005-03-15)陽明電子報編輯小組醫學院李建賢院長上任後,首要之務便安排行程,輕車簡從,逐一拜訪院內各單位,自3月3日起至3月17日止,李院長輪流至各系所問候單位同仁,以了解個別工作內容;同時也藉此機會進一步掌握各單位之特質Item type:Item, Item type:Item, 醫學生物技術研究所演講公告(國立陽明大學, 2005-03-15)陽明電子報編輯小組題目:The Role of Hypoxia on Molecular Regulation of Adipogenesis 講者:李易展博士 時間:94年3月25日 (五) 下午12:10-13:30 地點:研究大樓202室 經辦:醫學生物技術研究所Item type:Item, 台聯大尖端中心 329 WSN Workshop 活動訊息(國立陽明大學, 2005-03-15)陽明電子報編輯小組Wireless Sensor Network已成為國際大型研究計畫的趨勢,為因應此一潮流, 在國內WSN領域研究主題上有所突破,CAISER(尖端資訊系統與電子研究中心) 提供 WSN 自架構、硬軟體至應用等各層面的相關資訊並展現研究成果,以資 與國際、國內的學者專家們交流Item type:Item, Item type:Item, 從陽明大學到軍艦岩的自然步道(國立陽明大學, 2005-03-15)陽明電子報編輯小組本文為2000年3月間,總務處為規劃自校門口貫通至軍艦岩的自然步道,向台北市政府所提之企劃案。當時所拍攝之沿途設施與景觀,已在數年後的今天看出明顯差異。例如文末所提,正積極籌劃將校門口東側兩座舊倉庫及附近約四百坪空間建構為文化生活廣場之事,文化生活廣場已於2001年10月間正式開幕啟用,如今成為校園內最富文化氣息之建築物Item type:Item, ESD protection circuit(2005-03-15) ;Ker ;Ming-Dou ;LinKun-HsienThe claimed invention discloses an ESD protection circuit that is applied to an IC with power-down-mode operation. When the IC goes into power-down-mode operation, leakage current and charging from the I/O pad to the VDD power line could be prevented by applying the present invention. Therefore, the malfunction of the IC can be avoided. There still have two ESD clamp circuits respectively connected between the VDD power line and the VSS power line and between ESD bus line and VSS power line, so as to achieve the whole chip ESD protection scheme. The present invention can prevent ESD protection circuit from resulting in leakage current or malfunction under power-down-mode operation, and moreover achieve whole chip ESD protection scheme.