Browsing by Issue Date, starting with "2007-11-30"

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Evidence of tandem repeat and extra thiol-groups resulted in the polymeric formation of bovine haptoglobin: A unique structure of Hp 2-2 phenotype
(2007-11-30)
Lai, Yi An
;
Lai, I. Hsiang
;
Tseng, Chi Feng
;
Lee, James
;
Mao, Simon J. T.
Human plasma Hp is classified as 1-1, 2-1, and 2-2. They are inherited from two alleles Hp 1 and Hp 2, but there is only Hp 1 in almost all the animal species. Hp 2-2 molecule is extremely large and heterogeneous associated with the development of inflammatory-related diseases. In this study, we expressed entire bovine Hp in E. coli as a alpha beta linear form. Interestingly, the antibodies prepared against this form could recognize the subunit of native Hp. In stead of a complicated column method, the antibody was able to isolate bovine Hp via immunoaffinity and gel-filtration columns. The isolated Hp is polymeric containing two major molecular forms (660 and 730 kDa). Their size and hemoglobin binding complex are significantly larger than that of human Hp 2-2. The amino-acid sequence deducted from the nucleotide sequence is similar to human Hp 2 containing a tandem repeat over the cc chain. Thus, the Hp 2 allele is not unique in human. We also found that there is one additional -SH group (Cys-97) in bovine alpha chain with a total of 8 -SH groups, which may be responsible for the overall polymeric structure that is markedly different from human Hp 2-2. The significance of the finding and its relationship to structural evolution are also discussed.
Innovative three-axial actuator for high-density optical drive
(2007-12-01)
Lan, Yung-Sung
;
Tien, Chung-Hao
;
光電工程學系
;
顯示科技研究所
;
Department of Photonics
As the density in optical data storage systems increases, a drive capable of tilt control thus becomes necessary in order to improve the tilt margin as the coma aberration is accordingly increased. In this paper, we propose an innovative three-axial actuator based on a traditional four-wire scheme with an additional pair of tilting magnets. The proposed coil-driven servo can independently compensate 1 tilt degree associated with a torque variation of less than 5%. The driving forces of the focusing and tracking are kept constant while the tilt servo is activated.
Photocurrent suppression of transparent organic thin film transistors
(2007-12-01)
Chuang, Chiao-Shun
;
Tsai, Shu-Ting
;
Lin, Yung-Sheng
;
Chen, Fang-Chung
;
Shieh, Hang-Ping D.
Organic thin-film transistors (OTFTs) with high transmittance and low photosensitivity have been demonstrated. By using titanium dioxide nanoparticles as the additives in the polymer gate insulators, the level of device photoresponse has been reduced. The device shows simultaneously a high transparence and a minimal threshold voltage shift under white light illumination. It is inferred that the localized energy levels deep in the energy gap of pentacene behave as the recombination centers, enhancing substantially the recombination process in the conducting channel of the OTFFs. Therefore, the electron trapping is relieved and the shift of threshold voltage is reduced upon illumination.
Synthesis, composition optimization, and VUV photoluminescence characterization of (Y,Gd) (V,P) O-4 : Eu3+ as a potential red-emitting plasma-display panel phosphor
(2007-12-01)
Wu, Chia-Chin
;
Cheng, Bing-Ming
;
Chen, Teng-Ming
;
應用化學系
;
Department of Applied Chemistry
The synthesis, composition optimization, VUV Photoluminescence (PL) spectra, and optical properties, of (Y, Gd) (V, P)O-4 : Eu3+ phosphors were investigated by synchrotron radiation. The VUV PLE spectra and the correlation among VUV PL intensity, lambda(em), and Eu3+, Gd3+, and P-content were established. The PLE spectral studies showed that (Y, Gd) (V, P)O-4: Eu3+ exhibited significant absorption in the VUV range. The VUV PL intensity was found to enhance with PO43- and Gd3+ -doping. Furthermore, the chromaticity characteristics of (Y, Gd) (V, P)O-4: Eu3+ were also found to be (0.6614, 0.3286) and compared against (Y, Gd)BO3:Eu3+ as a reference. Based on the characterization results, we are currently improving and evaluating the potential application of (Y, Gd) (V, P)O-4: Eu3+ as a new red-emitting PDP phosphor.
具有低電壓元件設計之混合電壓輸入／輸出緩衝器
(2007-12-01)
柯明道
;
陳世倫
一種具有低電壓元件設計之混合電壓輸入/輸出緩衝器,包含預驅動器、循軌單元、驅動單元、輸入/輸出接墊、浮接阱單元及輸送單元;預驅動器,用以接收第一資料信號及致能信號,及輸出第一及第二資料電壓;循軌單元,用以提供閘極循軌功能;驅動單元,耦接預驅動器及循軌單元,用以產生對應於第一資料電壓之第一緩衝電壓;輸入/輸出接墊,耦接至驅動單元,用以輸出第一緩衝電壓及接收第二資料信號;輸送單元,用以輸出對應於第二資料信號之第二緩衝電壓;以及浮接阱單元,耦接至驅動單元及輸入/輸出接墊,用以防止漏電流發生。
應用於信度傳播演算法的自動補償方法與裝置
(2007-12-01)
廖彥欽
;
林建青
;
張錫嘉
;
劉志尉
本發明提供一種用於信度傳播演算法之解碼的自動補償方法,在訊號雜訊比低時仍可有效修正誤差、改進解碼器效能及維持低硬體複雜度,包括:首先使用一最小和(min-sum)演算法來算出多個輸出値,藉以趨近於一信度傳播檢查端之運算結果;接著以一檢查條件來檢查目前解碼疊代次數;及最後若在前一步驟中,該目前解碼疊代次數被判定為一欲修正狀態時,則將該多個輸出値進行一補償程序;其中,係依據該信度傳播檢查端之一輸入値來動態選擇該補償項。本發明亦提供一種用於信度傳播演算法之解碼的自動補償裝置,係利用上述本發明之方法來加以執行的,其具備最小和演算單元及動態量化控制單元等裝置。
Customer order scheduling to minimize the number of late jobs
(2007-12-01)
Lin, B. M. T.
;
Kononov, A. V.
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資訊管理與財務金融系註：原資管所+財金所
;
Department of Information Management and Finance
In the order scheduling problem, every job (order) consists of several tasks (product items), each of which will be processed on a dedicated machine. The completion time of a job is defined as the time at which all its tasks are finished. Minimizing the number of late jobs was known to be strongly NP-hard. In this note, we show that no FPTAS exists for the two-machine, common due date case, unless P = NP. We design a heuristic algorithm and analyze its performance ratio for the unweighted case. An LP-based approximation algorithm is presented for the general multicover problem. The algorithm can be applied to the weighted version of the order scheduling problem with a common due date. (c) 2006 Elsevier B.V. All rights reserved.
Simulation of gear shaving with considerations of cutter assembly errors and machine setting parameters
(2007-12-01)
Hung, Ching-Hua
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Liu, Jia-Hung
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Chang, Shinn-Liang
;
Lin, Hung-Jeng
;
機械工程學系
Gear shaving is commonly used as a finishing process for gear manufacturing. The precision of the shaved gear tooth profile is highly dependent on both the parameter adjustments of the shaving machine and the cutter assembly errors. This paper develops the mathematical model of the shaved gear with crowning taking into account the setting parameters of the gear shaving machine and cutter assembly errors. The effects of the parameters on the work gear surface and the tooth lead crowning are also investigated. The results are thought to be relevant to the design, assembly, calibration, and control of a gear shaving machine.
壓電石英感測模組、晶片及系統
(2007-12-01)
黃國華
;
洪孟燕
;
汪孟德
一種壓電石英感測模組、晶片及系統,乃具有多個石英晶體震盪器,且利用多個第一電極分別將同一組的每個石英晶體震盪器加以串聯,再由多個第二電極分別將不同組的石英晶體振盪器之一加以串聯,如此構成的連接電路可將每一個石英晶體震盪器作定位,而可單獨啓動每一個石英晶體震盪器,藉以達到多樣品的即時偵測。
Synchronization of complex chaotic systems in series expansion form
(2007-12-01)
Ge, Zheng-Ming
;
Yang, Cheng-Hsiung
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機械工程學系
;
Department of Mechanical Engineering
This paper studies the synchronization of complex chaotic systems in series expansion form by Lyapunov asymptotical stability theorem. A sufficient condition is given for the asymptotical stability of an error dynamics, and is applied to guiding the design of the secure communication. Finally, numerical results are studied for the Quantum-CNN oscillators synchronizing with unidirectional/bidirectional linear coupling to show the effectiveness of the proposed synchronization strategy. (c) 2006 Elsevier Ltd. All rights reserved.
一種由微囊胞聚集體所構成的支架及其製造方法
(2007-12-01)
陳三元
;
劉澤英
;
劉典謨
一種由微囊胞聚集體所構成的組織工程支架及其製造方法,藉由乳化製程或是微脂體製程來形成囊胞,並透過控制材料特性及乳化條件,配合支架成形製程,使微囊胞自我堆積聚集組裝形成緊密結構,並可做為組織或細胞貼附、成長及分化之基底,還可以透過微囊胞預先包覆組織或細胞貼附、成長及分化過程中所需的藥物分子,使之同時發揮基底結構及藥物儲槽的雙重角色,並透過微囊胞特性近一步控制藥物釋放速率,達到藥物程序式釋放、協同釋放與穩定釋放的功能,且不易破壞藥物活性,並應用在組織工程及細胞培養的生醫元件上。
薛濤詞別案--賀夢蝶小病飛了
(2007-12-01)
管管
A fully-settled linear behavior plus noise model for evaluating the digital stimuli of the design-for-digital-testability Sigma-Delta modulators
(2007-12-01)
Hong, Hao-Chiao
;
電控工程研究所
;
Institute of Electrical and Control Engineering
Evaluating the digital stimuli used in the design-for-digital-testability (DfDT) Sigma-Delta modulator is a time-consuming task due to its oversampling and non-linear nature. Although behavioral simulations can substantially improve the simulation speed, conventional behavioral models fail to provide accurate enough signal-to-noise ratio (SNR) predictions for this particular application. In this paper, a fully-settled linear behavior plus noise (FSLB+N) model for the DfDT Sigma-Delta modulator is presented to improve both the accuracy and the speed of the behavioral simulations. The model includes the following parameters: the finite open-loop gains, the offsets, the finite output swings, the flicker noise of the operational amplifiers (OPAMPs), as well as the thermal noises of the switched capacitors, the OPAMPs, and the reference supplies. With the proposed model, the behavioral simulation results demonstrate a high correlation with the measurement data. On average, the SNR difference between the simulation and the measurement is -1.1 dB with a maximum of 0.05 dB and a minimum of -2.2 dB. Comparing with the circuit-level simulation using HSPICE, the behavioral simulation with the FSLB+N model is 1,190,000 times faster. The proposed model not only can be used for evaluating the digital stimulus candidates, but also can be applied to system-level simulations of the mixed-signal design with an embedded DfDT Sigma-Delta modulator.
Scanning the issue: Special issue on LCD TVs
(2007-12-01)
Kawamato, Hiro
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Shieh, Han-Ping D.
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Jang, J.
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電子工程學系及電子研究所
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Department of Electronics Engineering and Institute of Electronics
Nano-bubble flotation technology with coagulation process for the cost-effective treatment of chemical mechanical polishing wastewater
(2007-12-01)
Tsai, Jen-Chieh
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Kumar, Mathava
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Chen, Shen-Yi
;
Lin, Jih-Gaw
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環境工程研究所
The feasibility of nano-bubble flotation technology (NBFT) with coagulation/flocculation process for the enhanced treatment of chemical mechanical polishing (CMP) wastewater was investigated through laboratory and pilot-scale experiments. As a precursor, the effective combination of activator/collector was identified using a laboratory-scale flotation reactor. The results showed that polyaluminum chloride (PAC)/sodium oleate (NaOl) was the best combination of activator/collector, respectively and its application in the NBFT with coagulation process increased the wastewater clarification efficiency by 40% as compared with traditional coagulation/flocculation process. More than 95% turbidity, total solids and total silica removal efficiencies were observed in the pilot-scale flotation experiments. From the results, it was found that NBFT with coagulation process could be performed effectively at an optimum PAC concentration of 50-60 mg/L (as Al), NaOl concentration of 5-10 mg/L with a recycle ratio of 10-20% and I h hydraulic retention time HRT. The cost and performance assessment reflected that CMP wastewater could be treated efficiently at a minimum cost using the present approach. (c) 2007 Elsevier B.V. All rights reserved.
Functional gold nanoparticles as photothermal agents for selective-killing of pathogenic bacteria
(2007-12-01)
Huang, Wei-Chieh
;
Tsai, Pei-Jane
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Chen, Yu-Chie
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應用數學系
;
應用化學系分子科學碩博班
Aims: Our aim was to demonstrate that functional gold nanoparticles can be used as photothermal agents for the selective killing of pathogenic bacteria. Materials & methods: Gold nanoparticles with polygonal shapes, capable of absorbing near infrared (NIR) light, were generated through a photochemical reaction. Vancomycin, which can bind with the terminal D-Ala-D-Ala moieties of the peptide units of pathogen cell walls, was immobilized on the surface of the gold nanoparticles. The vancomycin-bound gold nanoparticles were used as the photothermal agents for the inhibition of pathogenic bacteria growth, under irradiation of NIR light (808 nm). Results & discussion: We have demonstrated that vancomycin-bound gold nanoparticles are capable of selective-binding onto the cell walls of pathogenic bacteria. A large portion (> 99%) of bacteria targeted by the gold nanoparticles was destroyed under illumination by NIR light within 5 min owing to suffering from heating. Conclusions: This photothermal approach is effective for the inhibition of pathogenic bacteria cell growth, including Gram-positive bacteria, Gram-negative bacteria and antibiotic-resistant bacteria.
TiO2/GeOxNy stacked gate dielectrics for Ge-MOSFETs
(2007-12-01)
Bera, M. K.
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Mahata, C.
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Chakraborty, A. K.
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Nandi, S. K.
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Tiwari, Jitendra N.
In this work, we present the results of physical and electrical characterization of Ti-based high-k gate dielectrics on Ge substrates. Titanium tetrakis isopropoxide (TTIP) was used as the organometallic source for the deposition of ultra-thin TiO2 films on p-Ge (100) at low temperature (< 200 degrees C) by plasma enhanced chemical vapor deposition (PECVD) technique in a microwave (700 W, 2.45 GHz) plasma cavity discharge system at a pressure of similar to 65 Pa. The presence of an ultra-thin lossy GeO2 interfacial layer between the deposited high-k film and the substrate, results in frequency-dependent capacitance-voltage (C-V) characteristics in strong accumulation and a high interface state density (similar to 10(13) cm(-2) eV(-1)). To improve the electrical properties, nitrogen engineering has been employed to convert the lossy GeO2 interfacial layer to its oxynitride, thus forming TiO2/GeOxNy/Ge stacked-gate structure with improved interface/electrical properties. Different N sources, such as NO, NH3 and NO/NH3, have been used for nitrogen engineering. XPS and Raman spectroscopy analyses have been used for surface morphological study. Electrical properties, such as gate leakage current density, interface state density, charge trapping, flatband voltage shift, etc, have been studied in detail for TiO2/GeOxNy/Ge MIS capacitors using the current-voltage (I-V), capacitance-voltage (C-V), conductance-voltage (G-V) and stress (both constant voltage and current) measurements. Although a significant improvement in electrical characteristics has been observed after nitridation in general, the formation of the interfacial GeOxNy layer, obtained from NO-plasma nitridation, is found to provide the maximum improvement among all the nitridation techniques used in this study. It is shown that the insertion of an ultra-thin oxynitride (GeOxNy) interfacial layer is advantageous for producing gate-quality TiO2 high-k dielectric stacks on Ge substrates.
Protein folding: An antagonistic reaction of spontaneous folding and diffusion limited aggregation in nature
(2007-12-01)
Chang, Chia-Ching
;
Kan, Lou-Sing
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生物科技學系
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Department of Biological Science and Technology
Protein folding may follow a spontaneous process or a reaction-path directed process, determined by various folding transition boundaries due to intrinsic properties of the protein. A general first-order-like state-transition model predicts that a protein might be trapped in an aggregated state when the folding path crosses the transition boundary. Both experimental study and molecular simulation indicated that protein within this particular transition region might involve intermolecular interactions. Therefore, a direct folding process may have been a combination of an antagonistic reaction of spontaneous folding and a diffusion limited aggregation. In this paper, the protein folding mechanism and the theoretical basis of time limited diffusion/aggregation process are elaborated. The application of auto-correlation function in time dependent biological studies is also discussed.
Reconfiguring the innovation policy portfolios for Taiwan's SIP Mall industry
(2007-12-01)
Huang, Chi-Yo
;
Shyu, Joseph Z.
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Tzeng, Gwo-Hshiung
;
科技管理研究所
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Institute of Management of Technology
Since the year 2000, silicon intellectual property (SIP), which can minimize the gap in 'design productivity' that exists with systems-on-chip (SOC), has become one of the most important factors in the development of integrated circuit (IC) products in the SOC era. Although SIP is very important for IC industry development, complicated business, technical as well as legal issues inside SIP transactions have hindered successful transactions and the integration of SIPS into SOCs. Thus, web-based SIP e-Commerce mechanisms, called SIP Malls, have emerged, aiming to resolve complex SIP issues. To maintain its leading position and competitiveness in the World's IC industry, as well as the value added by SOC products in Taiwanese IC firms, the Taiwanese government has developed SIP Malls, using innovation policy tools. However, the Taiwanese SIP Mall industry remains immature. No existing Taiwanese SIP Malls generate a profit or account for a significant share of worldwide SIP transactions. This research will develop an analytical framework for defining an innovation policy portfolio that aims to develop Taiwan's SIP Mall industry, so that it will enhance the value added of SIP Malls and, thus, the nation's competitiveness in the SIP and IC industries, something which already has become one of the Taiwanese government's major concerns. The industry innovation requirements (IIRs) are summarized using the Delphi method. Meanwhile, the major IIRs identified by Decision Making Trial and Evaluation Laboratory (DEMATEL) are introduced. After the IIRs are derived, the relationships between the IIRs and innovation policy tools are derived by Grey relational analysis (GRA). Then, the innovation policy tools are clustered, based upon the Grey grades derived by GRA. Finally, reconfigured innovation policy portfolios are presented for the Taiwanese government's policy definition. The results demonstrate that developing an innovative policy portfolio that includes scientific, technical, educational, public enterprise, information, legal and regulatory, financial, and taxation policy tools will be the most necessary step towards developing Taiwan's SIP Mall industry. (c) 2007 Elsevier Ltd. All rights reserved.
Thermal and electrical transport properties of a single nickel nanowire
(2007-12-01)
Ou, M. N.
;
Harutyunyan, S. R.
;
Lai, S. J.
;
Chen, C. D.
;
Yang, T. J.
The thermal conductivity (K), specific heat (C-p) and the resistivity (p) of a single nickel nanowire have been measured in the temperature range from 4 to 300 K by means of the "self heating 3 omega" technique. Starting with a 100 nm nickel film grown on a Si/Si3N4 substrate by thermal evaporation, a suspended nickel nanowire was then fabricated through e-beam lithography and etching processes. The width and length of the wire were determined by scanning electron microscope (SEM) as 180 nm and 35 mu m respectively. At 300 K the thermal conductivity of nanowire is similar to 20% of the bulk, it diminishes to lower value as temperature decreases. The consequence is opposite to that of the bulk and might be explained by the ristriction of mean free paths of electron/phonon-phonon interactions due to the grain boundaries. An enhancement of specific heat similar to 250% of the bulk is also observed. In addition, the resistivity of nanowire at room temperature is about four times larger than that of the bulk. The small relative resistiv-ity ratio (RRR) confirms the polycrystalline characteristic ofthe nanowire.