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Item type:Item, 文章產生系統及方法(2010-02-16) ;李嘉晃 ;余思翰陳智維本發明提供一種文章產生系統。該文章產生系統包含綜合語料庫、特定主題語料庫、判斷模組、決定模組、選取模組及組合模組。當特定主題被決定時,判斷模組根據綜合語料庫與特定主題語料庫產生對應於特定主題之複數個主題關鍵詞。決定模組根據複數個主題關鍵詞從特定主題語料庫中決定複數個填充字串。選取模組自複數個主題關鍵詞中選出複數個目標關鍵詞,並根據複數個目標關鍵詞從複數個填充字串中選出複數個候選填充字串。組合模組根據複數個目標關鍵詞與複數個候選填充字串形成與特定主題相關之文章。Item type:Item, 數位式快速鎖定頻率合成器(2010-02-16) ;陳巍仁楊松諭本發明主要為一種數位式鎖相迴路頻率合成裝置,具有高速鎖定以及低相位雜訊特性。其中鎖相迴路由一相位偵測器、可控制振盪器、自動動態調整迴路增益之迴路濾波器、回授相位積分電路、參考相位積分電路所組成。在迴路鎖定過程中,透過自動動態調整迴路增益之迴路濾波器,偵測積分電路輸出資訊以及相位偵測電路輸出資訊,動態的調整迴路濾波器中直饋路徑以及積分路徑的增益,使迴路鎖定速度加快。本案並提出一種高速計數器的電路,透過一組非同步計數器、資料擷取暫存器與取樣相位產生器,達成高速低功率之計數器。Item type:Item, 三維互動式顯示器及其三維座標偵測方法(2010-02-16) ;黃乙白 ;王國振 ;白宗緯吳璧丞本發明係揭露一種三維互動式顯示器及其三維座標偵測方法,利用安裝複數光柵片於一觸控面板上,使一觸控物接近此觸控面板所造成之陰影強度產生不對稱之分佈,再經由裝設於此觸控面板內之複數光源感測器偵測光源強度,其後藉由一處理單元,將此光源感測器所偵測到的光源強度做適當的運算以得到三維坐標。如此以提升此三維互動式顯示器在近距離的工作範圍,並且不須改變此三維互動式顯示器的製造程序與額外增加硬體設備。Item type:Item, 具光電池充電式影像感測裝置(2010-02-16) ;林進燈 ;洪紹航 ;李俊彥鍾仁峯本發明是揭示一種具光電池充電式影像感測裝置,係是由互補式金氧半導體影像感測器利用充電核心電路之光電二極體本身特性,操作在光電池區(亦稱太陽能電池區)而非一般操作在光傳導區,利用太陽能電池儲能方式將外部光源儲存在電路內部,利用此方法將該影像感測器動作之感光、充電功能,利用在佈局(Layout)感光面積上擁有該兩種功能,而改善傳統必須在不同佈局面積上做單一動作,以節省佈局面積降低成本。Item type:Item, 利用斜向沈積形成之奈米結構薄膜及其方法(2010-02-16) ;張家華 ;楊勁生 ;邱清華 ;余沛慈郭浩中本發明提出了一種利用斜向沈積技術形成之透明導電氧化物奈米結構及其方法。該方法使用電子槍來蒸鍍靶材,其蒸鍍基板設置在多個可轉動傾斜的平板上,並具有氣體控制閥控制氣體的通入,及一加熱源控制腔體內溫度,並於蒸鍍後進行退火製程,以改善薄膜結構與光電性質。Item type:Item, Method of symbol detection for MIMO dual-signaling uplink CDMA systems(2010-02-16) ;Ho ;Chung-Lien ;Wu ;Jwo-YuhLeeThe invention provides a block-wise successive interference cancellation (SIC) detection algorithm for a general multi-input multi-output (MIMO) CDMA system over the frequency-selective channels, in which each user's data stream can be simultaneously applied with orthogonal space-time block encoding for transmit diversity or spatially multiplexing for high spectral efficiency according to the channel conditions. For such the considered dual-signaling system, the receiver could suffer from the large dimension data processing. A two-stage approach for block-wise SIC detection algorithm is thus proposed to further reduce the computational complexity.Item type:Item, 利用超音波與電腦視覺偵測之自動導航裝置及其導航方法(2010-02-16) ;吳至仁 ;蔡雙圓蔡文祥本發明係揭露一種利用超音波與電腦視覺偵測之自動導航裝置及其導航方法,首先讓一使用者帶領一自動導航裝置,使自動導航裝置學習並規劃一航行路徑,接著使自動導航裝置獨立導航,且於此時可利用超音波與電腦視覺偵測周圍環境,並藉此比對航行路徑,以校正自動導航裝置之實際航行路線,本發明可讓不會使用電腦的普羅大眾,不必接觸電腦,也能使用自動移動裝置作互動,加以本發明是利用電腦視覺及超音波偵測,更能降低製造商在硬體方面的成本。Item type:Item, 色序法顯示器之顯示方法(2010-02-16) ;魏景明 ;黃乙白 ;林芳正謝漢萍本發明係為一種色序法顯示器之顯示方法,其包括下列步驟:分析目標影像;輸出第一色場影像;輸出第二色場影像;以及輸出第三色場影像。由於輸出之每一色場影像皆可顯示全彩之影像,且第一色場影像可正確顯示目標影像中之一色光之影像強度,並有效降低第二及第三色場影像之彩度及亮度,所以可有效改善色分離現象。Item type:Item, Identification and clinical association of anti-cytokeratin 18 autoantibody in COPD(2010-02-16) ;Kuo, Yung-Bin ;Chang, C. Allen ;Wu, Yao-Kuang ;Hsieh, Meng-JerTsai, Chung-HsienThe etiology of chronic obstructive pulmonary disease (COPD) remains unclear. A mechanism involving the autoimmune reaction in the pathogenesis of COPD has been proposed but not confirmed. The aim of this study was to investigate whether serum autoantibodies against pulmonary cellular proteins are present in COPD patients and to identify their autoantigens if possible. Samples from 50 COPD patients and 42 control subjects were studied. Circulating autoantibodies were detected by Western blot. Immunoprecipitation and matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry were used to identify the autoantigens. Autoantibodies against pulmonary cellular antigens were found in the sera of COPD patients. Specifically, an autoantibody against the 45-kDa human cytokeratin 18 protein was found in 76.0% of COPD patients and 23.8% of control subjects (p < 0.001). Furthermore, the cytokeratin 18 autoantibody level was positively correlated with the FEV(1) (L) (p = 0.013) and FEV(1) (%pred.) (p, = 0.043) values observed in COPD patients. This study identified the pulmonary epithelial cytokeratin 18 protein as a COPD-associated autoantigen and found that anti-cytokeratin 18 autoantibodies were prevalent in COPD patients. Our results support the hypothesis that humoral autoimmunity may be involved in the pathogenesis of COPD. (C) 2009 Elsevier B.V. All rights reserved.Item type:Item, Spatiotemporal Characterization of Phagocytic NADPH Oxidase and Oxidative Destruction of Intraphagosomal Organisms in Vivo Using Autofluorescence Imaging and Raman Microspectroscopy(2010-02-17) ;Chang, Wei-Tien ;Yang, Yi-Cyun ;Lu, Hsueh-Han ;Li, I-LinLiau, IanThe ability to generate antimicrobial reactive-oxygen species (ROS) by reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase is critical for the host to defend against invading microbes. We have demonstrated the application of confocal autofluorescence microscopy and Raman microspectroscopy to characterize dynamically the phagocytic process of living macrophages in a label-free manner. In particular, we visualized the translocation of NADPH oxidases in livin macrophages that are undergoing phagocytosis of invading yeasts and monitored dynamically the change at the molecular level of single intraphagosomal yeasts caused by phagocytic ROS.Item type:Item, Nanostructured thin-film formed by utilizing oblique-angle deposition and method of the same(2010-02-18) ;Chang, Chia-Hua ;Yang, Chin-Sheng ;Chiu, Ching-Hua ;Yu, Pei-ChenKuo, Hao-ChungThe present invention discloses a transparent conductive nanostructured thin-film by oblique-angle deposition and method of the same. An electron beam system is utilized to evaporate the target source. Evaporation substrate is disposed on a plurality of adjustable sample stage. Multiple gas control valve and heat source is provided to control the gas flow and temperature within the process chamber. An annealing process is performed after the evaporation to improve the thin-film structure and optoelectronic properties.Item type:Item, Modulation of Donor-Acceptor Interface through Thermal Treatment for Efficient Bilayer Organic Solar Cells(2010-02-18) ;Kekuda, Dhananjaya ;Huang, Jen-Hsien ;Ho, Kuo-Chuan ;Chu, Chih-Wei光電工程學系In this article, we demonstrate the effect of donor-acceptor (D-A) interface on the performance of bilayer organic solar cells. Solution processing was used to develop liquid crystal poly(9,9'-dioctylfluorene-co-bithiophene) (F8T2) polymer films and variable morphology of the films was achieved by varying the annealing temperature. The morphology of the annealed active layers signature a well-aligned nanodomain feature with an interdegitated structure at 200 degrees C. The devices with bilayer configuration, ITO/PEDOT:PSS/F8T2/C(70)/Al, have yielded a power conversion efficiency (PCE) of 3.4(+/- 0.2)% under 1 sun incident radiation. We attribute the high PCE to the increased D-A junction interface and balanced charge transport between electron/hole transport layers.Item type:Item, DIGITAL FAST-LOCKING FREQUENCY SYNTHESIZER(2010-02-18) ;CHEN, WEI-ZENYANG, SONG-YUA digital PLL frequency synthesizer characterized by fast-locking and low-jitters is presented. The PLL comprises a phase detector, a controllable oscillator, a loop filter having an automatically-adjusted loop gain, a feedback phase integration circuit, and a reference phase integration circuit. Fast-locking is achieved by dynamically adjusting forward-path gain and integral-path gain according to the output of the phase detector and the output of the integral-path during phase tracking. A skew-compensated counter circuit is proposed, which incorporates an asynchronous counter, a data register and a sample phase generator and features high-speed and low-power operation.Item type:Item, Structure and photoluminescence properties of strong blue-emitting alumina film developed from a liquid sol at low temperature(2010-02-18) ;Peng, Cheng-Hsiung ;Hwang, Chyi-Ching ;Hsiao, Chi-Sheng ;材料科學與工程學系Department of Materials Science and EngineeringStrong blue photoluminescence emission at 450 nm from alumina films prepared from an alumina precursor was observed. Photo luminescence measurements indicate that the peak intensity of the blue emission changes with the pH value of the peptizing solution, the annealing temperature and the atmosphere. The blue emission appears at a low temperature of 50 degrees C and reaches a maximum strength at 400 degrees C in an oxygen atmosphere and 600 degrees C in a nitrogen atmosphere. HRTEM images show that the alumina films are composed of nanoparticles with a diameter of <= 10 nm. it is believed that the observed strong photoluminescence is associated with inherent defect centers in the material, where these are related to the structure transition and transformation from the boehmite phase to the gamma-alumina phase and bond cleavage. (C) 2009 Elsevier B.V. All rights reserved.Item type:Item, AUTOMATIC ULTRASONIC AND COMPUTER-VISION NAVIGATION DEVICE AND METHOD USING THE SAME(2010-02-18) ;WU, Chih-Jen ;TSAI, Shung-YungTSAI, Wen-HsiangThe present invention discloses an automatic ultrasonic and computer-vision navigation device and a method using the same. In the method of the present invention, the user guides an automatic navigation device to learn and plan a navigation path; next, the automatic navigation device navigates independently and uses ultrasonic signals and computer vision to detect the environment; then, the automatic navigation device compares the detected environment data with the navigation path to amend the physical movement track. The present invention enables ordinary persons to interact with the automatic navigation device without operating the computer. As the present invention adopts computer vision and ultrasonic signals to realize the functions thereof, the manufacturers can save the hardware cost.Item type:Item, 感測裝置(2010-02-21) ;鄭璧瑩黃健寶本發明係提供一種感測裝置,係應用一半球形容器裝載液態介電質,利用半球形容器內兩對以上之電極端,以供液態介電質觸發電極來導通電路,而此容器外圍是以抗腐蝕材料包覆之;一緩衝頸縮口及一精度閥,設置於容器上,以避免該液態介電質與電極產生接觸,達成避免震動之干擾及調節液態介電質的液面高度改變感測裝置之靈敏度;以及一防漏感測裝置,係包覆半球形容器、液態介電質、緩衝頸縮口、精度閥,以防止該液態介電質洩漏,達成一個多方向可控制、偵測、調整傾斜功能之感測器。 【創作特點】 本發明之主要目的係提供一種感測裝置,係利用一容器來裝載液態介電質,再配合兩對以上之電極來達成具有可調整多向性水平的控制。 本發明之另一目的係提供一種感測裝置,其係裝置一精度閥,而能改變感測裝置靈敏度之功能。 本發明之再一目的係提供一種感測裝置,其係裝置一防漏感測裝置,作為防止液態介電質溢漏的第二防線。 為達到上述之目的,本發明係提供一種感測裝置,係利用一半球形容器裝載液態介電質,而其外圍以抗腐蝕材料將容器包覆之,在容器內設有兩對電極端,以供液態介電質觸發來導通電路;在容器上設有一緩衝頸縮口及一精度閥,分別避免液態介電質與電極產生接觸達成防震之功能及調節液態介電質的液面高度,並另外使用一防漏感測裝置將半球形容器、液態介電質、緩衝頸縮口、精度閥包覆,以防止該液態介電質洩漏,作為第二層防線。 底下藉由具體實施例配合所附的圖式詳加說明,當更容易瞭解本發明之目的、技術內容、特點及其所達成之功效。Item type:Item, High-excitation effect on photoluminescence of sol-gel ZnO nanopowder(2010-02-22) ;Chia, C. H. ;Lai, Y. J. ;Han, T. C. ;Chiou, J. W.Hu, Y. M.We studied the power-dependent photoluminescence of ZnO nanopowder grown by sol-gel method at low temperature. At moderate optical pumping intensity, two nonlinear emission bands due to the radiative recombination of free biexciton and the inelastic exciton-exciton scattering were detected. We found that the threshold of the excitation density for the emergence of the nonlinear emission bands is low (< 18 W/cm(2)) in sol-gel ZnO nanopowders.Item type:Item, 交大e-News第065期(2010-02-22) ;Secretariat國立交通大學秘書室Item type:Item, Pyrazole compound BPR1P0034 with potent and selective anti-influenza virus activity(2010-02-23) ;Shih, Shin-Ru ;Chu, Tzu-Yun ;Reddy, Gadarla Randheer ;Tseng, Sung-NainChen, Hsiun-LingBackground: Influenza viruses are a major cause of morbidity and mortality around the world. More recently, a swine-origin influenza A (H1N1) virus that is spreading via human-to-human transmission has become a serious public concern. Although vaccination is the primary strategy for preventing infections, influenza antiviral drugs play an important role in a comprehensive approach to controlling illness and transmission. In addition, a search for influenza-inhibiting drugs is particularly important in the face of high rate of emergence of influenza strains resistant to several existing influenza antivirals. Methods: We searched for novel anti-influenza inhibitors using a cell-based neutralization (inhibition of virus-induced cytopathic effect) assay. After screening 20,800 randomly selected compounds from a library from ChemDiv, Inc., we found that BPR1P0034 has sub-micromolar antiviral activity. The compound was resynthesized in five steps by conventional chemical techniques. Lead optimization and a structure-activity analysis were used to improve potency. Time-of-addition assay was performed to target an event in the virus life cycle. Results: The 50% effective inhibitory concentration (IC(50)) of BPR1P0034 was 0.42 +/- 0.11 mu M, when measured with a plaque reduction assay. Viral protein and RNA synthesis of A/WSN/33 (H1N1) was inhibited by BPR1P0034 and the virus-induced cytopathic effects were thus significantly reduced. BPR1P0034 exhibited broad inhibition spectrum for influenza viruses but showed no antiviral effect for enteroviruses and echovirus 9. In a time-of-addition assay, in which the compound was added at different stages along the viral replication cycle (such as at adsorption or after adsorption), its antiviral activity was more efficient in cells treated with the test compound between 0 and 2 h, right after viral infection, implying that an early step of viral replication might be the target of the compound. These results suggest that BPR1P0034 targets the virus during viral uncoating or viral RNA importation into the nucleus. Conclusions: To the best of our knowledge, BPR1P0034 is the first pyrazole-based anti-influenza compound ever identified and characterized from high throughput screening to show potent (sub-mu M) antiviral activity. We conclude that BPR1P0034 has potential antiviral activity, which offers an opportunity for the development of a new anti-influenza virus agent.Item type:Item, Reconstructing genome trees of prokaryotes using overlapping genes(2010-02-24) ;Cheng, Chih-Hsien ;Yang, Chung-Han ;Chiu, Hsien-Tai ;Lu, Chin Lung生物科技學系Background: Overlapping genes (OGs) are defined as adjacent genes whose coding sequences overlap partially or entirely. In fact, they are ubiquitous in microbial genomes and more conserved between species than nonoverlapping genes. Based on this property, we have previously implemented a web server, named OGtree, that allows the user to reconstruct genome trees of some prokaryotes according to their pairwise OG distances. By analogy to the analyses of gene content and gene order, the OG distance between two genomes we defined was based on a measure of combining OG content (i.e., the normalized number of shared orthologous OG pairs) and OG order (i.e., the normalized OG breakpoint distance) in their whole genomes. A shortcoming of using the concept of breakpoints to define the OG distance is its inability to analyze the OG distance of multi-chromosomal genomes. In addition, the amount of overlapping coding sequences between some distantly related prokaryotic genomes may be limited so that it is hard to find enough OGs to properly evaluate their pairwise OG distances. Results: In this study, we therefore define a new OG order distance that is based on more biologically accurate rearrangements (e. g., reversals, transpositions and translocations) rather than breakpoints and that is applicable to both uni-chromosomal and multi-chromosomal genomes. In addition, we expand the term "gene" to include both its coding sequence and regulatory regions so that two adjacent genes whose coding sequences or regulatory regions overlap with each other are considered as a pair of overlapping genes. This is because overlapping of regulatory regions of distinct genes suggests that the regulation of expression for these genes should be more or less interrelated. Based on these modifications, we have reimplemented our OGtree as a new web server, named OGtree2, and have also evaluated its accuracy of genome tree reconstruction on a testing dataset consisting of 21 Proteobacteria genomes. Our experimental results have finally shown that our current OGtree2 indeed outperforms its previous version OGtree, as well as another similar server, called BPhyOG, significantly in the quality of genome tree reconstruction, because the phylogenetic tree obtained by OGtree2 is greatly congruent with the reference tree that coincides with the taxonomy accepted by biologists for these Proteobacteria. Conclusions: In this study, we have introduced a new web server OGtree2 at http://bioalgorithm.life.nctu.edu.tw/ OGtree2.0/ that can serve as a useful tool for reconstructing more precise and robust genome trees of prokaryotes according to their overlapping genes.