Browsing by Issue Date, starting with "2011-07-11"

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最佳空間-時間-頻率區塊碼之搜尋方法及其多輸入多輸出之多頻帶超寬頻系統
(2011-07-11)
王蒞君
;
劉維正
一種最佳空間－時間－頻率(space－time－frequency，STF)區塊碼之搜尋方法能夠以較少的運算量，有系統地搜尋出最佳之空間－時間－頻率區塊碼。同時亦揭露一種多輸入多輸出之多頻帶超寬頻系統，其以上述之最佳STF區塊碼進行編碼，以使位元錯誤率達到最小。
16-Hydroxycleroda-3,13-dien-15,16-olide deregulates PI3K and Aurora B activities that involve in cancer cell apoptosis
(2011-07-11)
Lin, Yi-Hsiung
;
Lee, Chien-Chih
;
Chan, Wen-Li
;
Chang, Wen-Hsin
;
Wu, Yang-Chang
The PI3K-AKT pathway and Aurora kinase play essential roles in such cellular processes as cell survival, angiogenesis, and differentiation, and are usually expressed at maximum levels during cancer cell proliferation. The present study investigated the effect of the natural compound, 16-hydroxycleroda-3,13-dien-15,16-olide (PL3), on regulating the PI3K-AKT pathway and Aurora B, which led to cancer cell apoptosis. PL3 acts as a PI3K inhibitor by influencing cell survival, signaling transduction, and cell cycle progression. It was observed that PL3 targeted and induced dephosphorylation of the PI3K pathway, degradation of Aurora B and mitotic-related gene expressions, and sequentially shut down the cell cycle. This eventually resulted in cell death. As Aurora B was downregulated, spindle dysfunction and destruction of the G(2)/M phase checkpoint resulted in DNA-damaged cells undergoing apoptosis. Moreover. PL3 also resensitized T31 5I-mutated Bcr-ABL(+) BA/F3 cells to improve the cytotoxicity of Imatinib in Imatinib-resistant cell line. Taken together, PL3 can perturb the PI3K-AKT pathway and Aurora B resulting in gene silencing and cell cycle disturbance. It was demonstrated that PL3 acted like a novel small-molecule PI3K modulator, thereby potentially contributing to cancer chemotherapy and combination medication. (C) 2011 Elsevier Ireland Ltd. All rights reserved.
無線網路中執行換手程序的裝置與方法
(2011-07-11)
林一平
;
許世芬
一種無線網路中執行換手程序的裝置與方法。此裝置包含一處理機執行一識別碼檢查機制，當無線網路用戶欲從一來源存取點移動至一目的地存取點時，無線網路用戶傳送一認證要求訊息至目的地存取點，識別碼檢查機制將認證要求訊息內的一R0金鑰持有者識別碼向此目的地存取點的一R0KH表查詢，並決定出正確換手程序的一設定參數，依此讓該無線網路用戶執行換手程序。目的地存取點之R0KH表是由在此目的地存取點網域範圍下可被其存取之所有R0金鑰持有者的識別碼來組成。
Optical properties of self assembled GaN polarity inversion domain boundary
(2011-07-11)
Liu, M. -C.
;
Cheng, Y. -J.
;
Chang, J. -R.
;
Hsu, S. -C.
;
Chang, C. -Y.
We report the fabrication of GaN lateral polarity inversion heterostructure with self assembled crystalline inversion domain boundaries (IDBs). The sample was fabricated by two step molecular-beam epitaxy (MBE) with microlithography patterning in between to define IDBs. Despite the use of circular pattern, hexagonal crystalline IDBs were self assembled from the circular pattern during the second MBE growth. Both cathodoluminescent (CL) and photoluminescent (PL) measurements show a significant enhanced emission at IDBs and in particular at hexagonal corners. The ability to fabricate self assembled crystalline IDBs and its enhanced emission property can be useful in optoelectronic applications. (C) 2011 American Institute of Physics. [doi: 10.1063/1.3610449]
Investigating the degradation behavior caused by charge trapping effect under DC and AC gate-bias stress for InGaZnO thin film transistor
(2011-07-11)
Chen, Te-Chih
;
Chang, Ting-Chang
;
Hsieh, Tien-Yu
;
Lu, Wei-Siang
;
Jian, Fu-Yen
This letter investigates the degradation mechanism of amorphous indium-gallium-zinc oxide thin-film transistors under gate-bias stress. The larger V(t) shift under positive AC gate-bias stress when compared to DC operation indicates that an extra electron trapping mechanism occurs during rising/falling time during the AC pulse period. In contrast, the degradation behavior under illuminated negative gate-bias stress exhibits the opposite degradation tendency. Since electron and hole trapping are the dominant degradation mechanisms under positive and illuminated negative gate-bias stress, respectively, the different degradation tendencies under AC/DC operation can be attributed to the different trapping efficiency of electrons and holes. (C) 2011 American Institute of Physics. [doi: 10.1063/1.3609873]
Tone-interleaved coded modulation scheme for MIMO OFDM communication
(2011-07-12)
Wu Wen-Rong
;
Shen Shih-Chi
A MIMO OFDM system for TICM includes a tone-level interleaver at the transmitter using a block of NT symbols as its basic unit. This results in different decoding architectures at the receiver. The main advantage of TICM is to merge soft-bit demapping into the Viterbi algorithm. Taking advantage of the trellis structure inherent in the Viterbi algorithm, TICM can have lower computational complexity and potentially better performance than BICM with the LSD detector and the vector demapper. Although the tone-level interleaving may not have spatial diversity gain, the performance is not affected in 802.11n environments.
Light emitter device
(2011-07-12)
Chang Chun-Yen
;
Yang Tsung Hsi
A light emitting device (LED) structure formed on a Group IV-based semiconductor substrate is provided. The LED structure includes a Group IV-based substrate, an AlN nucleation layer formed on the Group IV-based substrate, a GaN epitaxial layer formed on the AlN nucleation layer, a distributed Bragg reflector (DBR) multi-layer structure formed on the epitaxial layer, and an LED active layer formed on the DBR multi-layer structure.
Digital fast-locking frequency synthesizer
(2011-07-12)
Chen Wei-Zen
;
Yang Song-Yu
A digital PLL frequency synthesizer characterized by fast-locking and low-jitters is presented. The PLL comprises a phase detector, a controllable oscillator, a loop filter having an automatically-adjusted loop gain, a feedback phase integration circuit, and a reference phase integration circuit. Fast-locking is achieved by dynamically adjusting forward-path gain and integral-path gain according to the output of the phase detector and the output of the integral-path during phase tracking. A skew-compensated counter circuit is proposed, which incorporates an asynchronous counter, a data register and a sample phase generator and features high-speed and low-power operation.
Suspended nanochannel transistor structure and method for fabricating the same
(2011-07-12)
Lin Horng-Chih
;
Su Chun-Jung
;
Hsu Hsing-Hui
;
Li Guan-Jang
The present invention discloses a suspended nanochannel transistor structure and a method for fabricating the same. The transistor structure of the present invention comprises a substrate; a side gate formed on the substrate; a dielectric layer covering the substrate and the side gate; a suspended nanochannel formed beside the lateral of the side gate with an air gap existing between the suspended nanochannel and the dielectric layer; a source and a drain formed over the dielectric layer and respectively arranged at two ends of the suspended nanochannel. The electrostatic force of the side gate attracts or repels the suspended nanochannel and thus fast varies the equivalent thickness of the side-gate dielectric layer. Thereby, the on/off state of the element is rapidly switched, or the initial voltage of the channel is altered.
METHOD FOR FABRICATING A RESISTOR FOR A RESISTANCE RANDOM ACCESS MEMORY
(2011-07-14)
TSENG Tseung-Yuen
;
Wang Sheng-Yu
;
Tsai Chen-Han
A method for fabricating a resistor for a resistance random access memory (RRAM) includes: (a) forming a first electrode over a substrate; (b) forming a variable resistance layer of zirconium oxide on the first electrode under a working temperature, which ranges from 175° C. to 225° C.; and (c) forming a second electrode of Ti on the variable resistance layer.
Planar band-notched ultra-wideband antenna with square-looped and end-coupled resonator
(2011-07-14)
Wu, S-J.
;
Tarng, J-H.
;
電信工程研究所
;
Institute of Communications Engineering
A square-looped and an end-coupled resonator used in a planar ultra-wideband (UWB) antenna to achieve band-notched performance are presented here. To obtain notched performance in the wireless local area network band, both the square-looped and end-coupled resonator are designed and placed in a fork-shaped UWB antenna centre. The characteristics and schematic equivalent circuit of each resonator are also discussed. Parametric studies of a fork-shaped antenna with square-looped resonator are given as an example to explore the operating mechanism. Accordingly, the band-notched antenna can effectively select target bands by adjusting different resonator structures. The proposed antenna features flat gain-frequency response and group delay as well as 10-25 dB gain suppression in the notched band.
Detection of autoantibodies against Rabphilin-3A-like protein as a potential biomarker in patient's sera of colorectal cancer
(2011-07-15)
Chen, Jinn-Shiun
;
Kuo, Yung-Bin
;
Chou, Yeh-Pin
;
Chan, Chung-Chuan
;
Fan, Chung-Wei
Background: Rabphilin-3A-like (RPH3AL) protein functions in the regulation of hormone exocytosis, and mutations in the RPHA3L gene have been associated with tumorigenesis in colorectal cancer (CRC). We evaluated the potential use of anti-RPH3AL autoantibodies as a marker for CRC detection. Methods: Sera from 84 patients with CRC and 63 healthy controls were analysed for the presence of RPH3AL autoantibodies with a Western blotting assay. Results: The frequencies of RPH3AL autoantibodies in the early stage, advanced stage and all CRC patients were 64.7%, 78.0% and 72.6%, respectively. These values are significantly higher than the frequency of RPH3AL autoantibodies in healthy controls (15.9%, P<0.001). Although the presence of RPH3AL autoantibodies did not correlate with clinical parameters, RPH3AL autoantibodies were found in 69.4% (34/49) of CRC patients who were negative for carcinoembryonic antigen. The value of the area under the receiver operating characteristic curve of RPH3AL autoantibody was 0.84, which suggests that screening for these autoantibodies could potentially be used for CRC diagnosis. Conclusion: Circulating RPH3AL autoantibodies are prevalent in patients with CRC, and detection of these autoantibodies might provide a novel non-invasive approach for CRC diagnosis. (C) 2011 Elsevier B.V. All rights reserved.
Numerical ranges of weighted shift matrices
(2011-07-15)
Tsai, Ming Cheng
;
Wu, Pei Yuan
;
應用數學系
;
Department of Applied Mathematics
We show that if A is an n-by-n (n >= 3) matrix of the form (sic) then the boundary of its numerical range contains a line segment if and only if the a(j)'s are nonzero and the numerical ranges of the (n - 1)-by-(n - 1) principal submatrices of A are all equal. For n = 3, this is the case if and only if vertical bar a(1)vertical bar = vertical bar a(2)vertical bar = vertical bar a(3)vertical bar not equal 0, in which case W (A), the numerical range of A, is the equilateral triangular region with vertices the three cubic roots of aia2a3. For n = 4, the condition becomes vertical bar a(1)vertical bar = vertical bar a(3)vertical bar not equal 0 and vertical bar a(2)vertical bar = vertical bar a(4)vertical bar not equal 0, in which case W (A) is the convex hull of two (degenerate or otherwise) ellipses. (C) 2011 Elsevier Inc. All rights reserved.
SNOSite: Exploiting Maximal Dependence Decomposition to Identify Cysteine S-Nitrosylation with Substrate Site Specificity
(2011-07-15)
Lee, Tzong-Yi
;
Chen, Yi-Ju
;
Lu, Tsung-Cheng
;
Huang, Hsien-Da
;
Chen, Yu-Ju
S-nitrosylation, the covalent attachment of a nitric oxide to (NO) the sulfur atom of cysteine, is a selective and reversible protein post-translational modification (PTM) that regulates protein activity, localization, and stability. Despite its implication in the regulation of protein functions and cell signaling, the substrate specificity of cysteine S-nitrosylation remains unknown. Based on a total of 586 experimentally identified S-nitrosylation sites from SNAP/L-cysteine-stimulated mouse endothelial cells, this work presents an informatics investigation on S-nitrosylation sites including structural factors such as the flanking amino acids composition, the accessible surface area (ASA) and physicochemical properties, i.e. positive charge and side chain interaction parameter. Due to the difficulty to obtain the conserved motifs by conventional motif analysis, maximal dependence decomposition (MDD) has been applied to obtain statistically significant conserved motifs. Support vector machine (SVM) is applied to generate predictive model for each MDD-clustered motif. According to five-fold cross-validation, the MDD-clustered SVMs could achieve an accuracy of 0.902, and provides a promising performance in an independent test set. The effectiveness of the model was demonstrated on the correct identification of previously reported S-nitrosylation sites of Bos taurus dimethylarginine dimethylaminohydrolase 1 (DDAH1) and human hemoglobin subunit beta (HBB). Finally, the MDD-clustered model was adopted to construct an effective web-based tool, named SNOSite (http://csb.cse.yzu.edu.tw/SNOSite/), for identifying S-nitrosylation sites on the uncharacterized protein sequences.
A bio-inspired two-layer multiple-walled carbon nanotube-polymer composite sensor array and a bio-inspired fast-adaptive readout circuit for a portable electronic nose
(2011-07-15)
Wang, L. C.
;
Tang, K. T.
;
Chiu, S. W.
;
Yang, S. R.
;
Kuo, C. T.
We report a fully integrated, portable, battery-operated electronic nose system comprising a bio-inspired two-layer multiple-walled carbon nanotube (MWNT)-polymer composite sensor array, a bio-inspired fast-adaptive readout circuit, and a microprocessor embedded with a pattern recognition algorithm. The two-layer MWNT-polymer composite sensor is simple to operate, and the membrane quality can be easily controlled. These two-layer membranes have improved sensitivity and stability. The fast-adaptive readout circuit responds to the sensor response, while tuning out the long-term constant background humidity, temperature, and odors. This portable electronic nose system successfully classified four complex alcohol samples 40 times for each sample; these samples were sake, sorghum liquor, medical liquor, and whisky. (C) 2011 Elsevier B.V. All rights reserved.
有機發光元件及其製法
(2011-07-16)
孟心飛
;
洪勝富
;
曾信榮
;
游佳達
;
葉重麟
提供一種有機發光元件，包括：第一電極；第二電極；介於該第一電極和第二電極之間的發光層，其中，該發光層包含本發明之式(I)化合物及式(II)化合物，其中，各取代基之定義係如說明書所界定；形成於該發光層與第一電極之間的第一載子傳輸層；以及形成於該發光層與第二電極之間的第二載子傳輸層。此外，用以製作本發明有機發光元件之全溶液製程可避免層間互溶，而獲致製作大面積元件及降低成本之優點。
電阻式隨存記憶體之製作方法
(2011-07-16)
曾俊元
;
王聖裕
;
蔡承翰
本發明提供一種電阻式隨存記憶體之製作方法，包含：(a)於一基材上形成一第一電極；(b)於該第一電極上以一175℃至225℃的製程溫度形成一氧化鋯之可變電阻層；及(c)於該可變電阻層上形成一Ti的第二電極。
壓電揚聲器及其之最佳化設計方法
(2011-07-16)
白明憲
;
蔡耀坤
本發明係揭露一種壓電揚聲器及其之最佳化設計方法，其中揚聲器結構係由框架固定至少一片壓電片，以壓電片來固定支撐振膜於框架內，而在壓電片與振膜之間設有一墊塊連接二者，此種揚聲器由於以穩定的框架固定壓電片，可加強平面揚聲器在低頻方面的頻率響應表現；另外，本發明之最佳化設計之方法以有限元素法建立壓電揚聲器之數學模型，進而模擬出揚聲器的聲壓負載，再利用模擬退火法來取得壓電揚聲器的結構最佳化之設計參數。
有機發光材料、使用該有機發光材料之有機發光元件及其製法
(2011-07-16)
孟心飛
;
洪勝富
;
曾信榮
;
游佳達
;
葉重麟
提供一種具有下式(I)之化合物：其中，各取代基之定義係如說明書所界定。該化合物可與其他有機發光材料合併用於有機發光元件發光層。本發明亦提供一種有機發光元件，係包括第一電極、第二電極、以及具有至少三層介於該第一電極與第二電極之間的有機材料層，其中，作為發光層的該層含有該式(I)化合物。此外，用以製作本發明有機發光元件之全溶液製程可避免層間互溶，而獲致製作大面積元件及降低成本之優點。
可參數化管線式快速傅利葉轉換硬體產生器
(2011-07-16)
黃俊達
;
王毓翔
;
林步青
;
周景揚
一種可參數化管線式快速傅利葉轉換硬體產生器，包括複數個包含第一蝶型運算的第一蝶型裝置，複數個包含該第一蝶型運算及一乘-i的複數乘法運算的第二蝶型裝置，複數個暫存器以及複數個連線陣列，其中，該連線陣列In之定義為、