Browsing by Issue Date, starting with "2011-10-04"

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1,3-Alternate Calix[4]arene as a Homobinuclear Ditopic Fluorescent Chemosensor for Ag+ Ions
(2011-10-04)
Ho, I-Ting
;
Haung, Kuan-Chang
;
Chung, Wen-Sheng
;
應用化學系
;
Department of Applied Chemistry
A novel 1,3-alternate calix[4]arene L, containing two different cationic binding sites of bis-triazoles and bis-enaminone groups, was synthesized and shown to be a homobinuclear ditopic fluorescent chemosensor for Ag+ ions. The fluorescence intensity of L was selectively enhanced by binding with Ag+ ions in methanol/chloroform (49:1, v/v) cosolvent. In the presence of most competing metal ions, L retains its selectivity toward Ag+ ion. The binding constants K-1 and K-2 of the successive complexation of L with the first and second Ag+ ions were calculated to be 4.46 x 10(3) and 9.20 x 10(4)M(-1), respectively. The higher K-2 value revealed that a positive allosteric effect participated in the complexation of L with the second equivalent of Ag+. Based on H-1 NMR titration results, we inferred that the two distal bis-enaminone and bis-triazole groups on L cooperatively coordinated to Ag+ ions with the help of cation-pi interactions from the phenoxy rings. Furthermore, the ESI-MS spectrometry clearly proved the formation of the homobinuclear complex L center dot(Ag+)(2), because a base peak at m/z of 750.1701 was detected and its isotope pattern was in excellent agreement with the calculated one.
1,3-Alternate Calix[4]arene as a Homobinuclear Ditopic Fluorescent Chemosensor for Ag(+) Ions
(2011-10-04)
Ho, I-Ting
;
Haung, Kuan-Chang
;
Chung, Wen-Sheng
;
應用化學系
;
Department of Applied Chemistry
A novel 1,3-alternate calix[4]arene L, containing two different cationic binding sites of bis-triazoles and bis-enaminone groups, was synthesized and shown to be a homobinuclear ditopic fluorescent chemosensor for Ag(+) ions. The fluorescence intensity of L was selectively enhanced by binding with Ag(+) ions in methanol/chloroform (49:1, v/v) cosolvent. In the presence of most competing metal ions, L retains its selectivity toward Ag(+) ion. The binding constants K(1) and K(2) of the successive complexation of L with the first and second Ag(+) ions were calculated to be 4.46 x 10(3) and 9.20 x 10(4)M(-1), respectively. The higher K(2) value revealed that a positive allosteric effect participated in the complexation of L with the second equivalent of Ag(+). Based on (1)H NMR titration results, we inferred that the two distal bis-enaminone and bis-triazole groups on L cooperatively coordinated to Ag(+) ions with the help of cation-pi interactions from the phenoxy rings. Furthermore, the ESI-MS spectrometry clearly proved the formation of the homobinuclear complex L center dot(Ag(+))(2), because a base peak at m/z of 750.1701 was detected and its isotope pattern was in excellent agreement with the calculated one.
Pore-Spanning Lipid Membrane under Indentation by a Probe Tip: A Molecular Dynamics Simulation Study
(2011-10-04)
Huang, Chen-Hsi
;
Hsiao, Pai-Yi
;
Tseng, Fan-Gang
;
Fan, Shih-Kang
;
Fu, Chien-Chung
We study the indentation of a free-standing lipid membrane suspended over a nanopore on a hydrophobic substrate by means of molecular dynamics simulations. We find that in the course of indentation the membrane bends at the point of contact and the fringes of the membrane glide downward intermittently along the pore edges and stop gliding when the fringes reach the edge bottoms. The bending continues afterward, and the large strain eventually induces a phase transition in the membrane, transformed from a bilayered structure to an interdigitated structure. The membrane is finally ruptured when the indentation goes deep enough. Several local physical quantities in the pore regions are calculated, which include the tilt angle of lipid molecules, the nematic order, the included angle, and the distance between neighboring lipids. The variations of the;e quantities reveal many detailed, not-yet-specified local structural transitions of lipid molecules under indentation. The force indentation curve is also studied and discussed. The results make a connection between the microscopic structure and the macroscopic properties and provide deep insight into the understanding of the stability of a lipid membrane spanning over nanopore.
Effective Mobility Enhancement by Using Nanometer Dot Doping in Amorphous IGZO Thin-Film Transistors
(2011-10-04)
Zan, Hsiao-Wen
;
Tsai, Wu-Wei
;
Chen, Chia-Hsin
;
Tsai, Chuang-Chuang
;
光電工程學系
交大e-News第103期
(2011-10-05)
Secretariat
;
國立交通大學秘書室
Diffuse-interface approach to rotating Hele-Shaw flows
(2011-10-05)
Chen, Ching-Yao
;
Huang, Yu-Sheng
;
Miranda, Jose A.
;
機械工程學系
;
Department of Mechanical Engineering
When two fluids of different densities move in a rotating Hele-Shaw cell, the interface between them becomes centrifugally unstable and deforms. Depending on the viscosity contrast of the system, distinct types of complex patterns arise at the fluid-fluid boundary. Deformations can also induce the emergence of interfacial singularities and topological changes such as droplet pinch-off and self-intersection. We present numerical simulations based on a diffuse-interface model for this particular two-phase displacement that capture a variety of pattern-forming behaviors. This is implemented by employing a Boussinesq Hele-Shaw-Cahn-Hilliard approach, considering the whole range of possible values for the viscosity contrast, and by including inertial effects due to the Coriolis force. The role played by these two physical contributions on the development of interface singularities is illustrated and discussed.
New SmCG Phases in a Hydrogen-Bonded Bent-Core Liquid Crystal Featuring a Branched Siloxane Terminal Group
(2011-10-05)
Chen, Wei-Hong
;
Chuang, Wei-Tsung
;
Jeng, U-Ser
;
Sheu, Hwo-Shuenn
;
Lin, Hong-Cheu
In this study, we synthesized three analogous bentcore molecules, a hydrogen-bonded complex and a covalent-bonded compound with branched siloxane units (H-SiO and C-SiO, respectively) and a hydrogen-bonded complex with an alkyl unit (H-Alk), and investigated the effects of the hydrogen bonding and branched siloxane terminal units on their mesomorphic properties. The covalent-bonded compound C-SiO and the hydrogen-bonded complex H-Alk exhibited typical SmCP phases; in contrast, the hydrogen-bonded complex H-SiO exhibited a series of general tilt smectic (SmCG) phases with highly ordered layer structures (i.e., SmCG(2)P(F)-USmCG(2)P(A)-SmCG(2)P(F)-SmCGP(F) upon cooling). During the SmCG-type phase transition process, a 2D-modulated ribbon structure transferred into highly ordered layers via undulated layers, as the hydrogen-bonding strength increased with reduced temperatures. As the SmCG domains were aligned under dc electric fields, a gradual decrease in the leaning angle from ca. 60 degrees to 50 degrees (while the tilt angle kept at ca. 31 degrees) could be determined by in situ wide-angle X-ray scattering (WAXS). Combined with Fourier transform infrared and Raman spectroscopic data, our results suggest that the change in the leaning angle was governed by the competition of the hydrogen bonds and microsegregation of siloxane units within the bilayer structure of the hydrogen-bonded complex H-SiO. In addition, the ferroelectric-(antiferroelectric)-ferroelectric transitions proven by the switching current responses in the SmCG-type phases of H-SiO reveal that the polar switching occurred through collective rotations around the long axis of H-SiO. Therefore, novel SmCG phases with a series of highly ordered 2D-structures were induced by the effects of the hydrogen bonding and branched terminal siloxane unit in the bent-core hydrogen-bonded LC complex H-SiO.
倫理與政治：馬基維利的《君王論》
(2011-10-05)
莊錦農
;
開放教育推動中心
;
Open Education Office
課程首頁本課程是由交通大學新文藝復興閱讀計畫提供。 96 年 8 月當各大學紛紛摩拳擦掌準備迎接新生的同時，交通大學校長吳重雨則因為一則來自於七月份泰晤士報，有關於英國首相布朗公布其夏日讀書清單的新聞中，看到了他對知識的尊重。在這同時，吳重雨校長也思考著，要如何為學生準備追求知識的環境和激發他們對知識的尊重與喜愛。台積電張忠謀董事長曾陳述他 18 歲進入哈佛那一年，博覽文史哲理工經典群籍，至此奠定了他求知的基礎，並借海明威名言，將其改為「哈佛這一年為人生可帶走的盛宴。」吳重雨校長以張董事長的學習為借鏡，認為學生固然能藉由自我閱讀的方式學習到豐沛的知識，但透過名人、大師親臨現場地介紹經典書籍，更能加深學子們對於書籍的認識與興趣，這也是「新文藝復興閱讀計劃」 ( 以下簡稱 : 「經典名著選讀」 ) 活動展開籌劃的緣由。於是，吳重雨校長便積極敦請「交大通識教育委員會」，接手籌備本計劃的相關活動，而該中心也成為實際施行本計畫的策動、開課以及認證單位。至此，期許交大學子藉由閱讀、聽講來提昇人文素養、開拓視野的「新文藝復興閱讀計劃」，就此展開。
The genomic features that affect the lengths of 5 ' untranslated regions in multicellular eukaryotes
(2011-10-05)
Chen, Chun-Hsi
;
Lin, Hsuan-Yu
;
Pan, Chia-Lin
;
Chen, Feng-Chi
;
生物科技學系
Background: The lengths of 5'UTRs of multicellular eukaryotes have been suggested to be subject to stochastic changes, with upstream start codons (uAUGs) as the major constraint to suppress 5'UTR elongation. However, this stochastic model cannot fully explain the variations in 5'UTR length. We hypothesize that the selection pressure on a combination of genomic features is also important for 5'UTR evolution. The ignorance of these features may have limited the explanatory power of the stochastic model. Furthermore, different selective constraints between vertebrates and invertebrates may lead to differences in the determinants of 5'UTR length, which have not been systematically analyzed. Methods: Here we use a multiple linear regression model to delineate the correlation between 5'UTR length and the combination of a series of genomic features (G+C content, observed-to-expected (OE) ratios of uAUGs, upstream stop codons (uSTOPs), methylation-related CG/UG dinucleotides, and mRNA-destabilizing UU/UA dinucleotides) in six vertebrates (human, mouse, rat, chicken, African clawed frog, and zebrafish) and four invertebrates (fruit fly, mosquito, sea squirt, and nematode). The relative contributions of each feature to the variation of 5'UTR length were also evaluated. Results: We found that 14%similar to 33% of the 5'UTR length variations can be explained by a linear combination of the analyzed genomic features. The most important genomic features are the OE ratios of uSTOPs and G+C content. The surprisingly large weightings of uSTOPs highlight the importance of selection on upstream open reading frames (which include both uAUGs and uSTOPs), rather than on uAUGs per se. Furthermore, G+C content is the most important determinants for most invertebrates, but for vertebrates its effect is second to uSTOPs. We also found that shorter 5'UTRs are affected more by the stochastic process, whereas longer 5'UTRs are affected more by selection pressure on genomic features. Conclusions: Our results suggest that upstream open reading frames may be the real target of selection, rather than uAUGs. We also show that the selective constraints on genomic features of 5'UTRs differ between vertebrates and invertebrates, and between longer and shorter 5'UTRs. A more comprehensive model that takes these findings into consideration is needed to better explain 5'UTR length evolution.
Method for reducing defects in epitaxially grown on the group III-nitride materials
(2011-10-06)
Chang Edward Yi
;
Wong Yuen Yee
The present invention discloses a method to grow group III-nitride materials on a non-native substrate with much reduced threading dislocation (TD) density and smooth surface by using MBE. The first layer is to suppress the formation of screw TD while the second layer is to bend the propagation of edge TD. After that, the migration enhanced epitaxy (MEE) approach is used to smoothen the second layer surface before a main layer of group III-nitride is growth to the thickness required for different applications. All of these steps are performed in the MBE reactor by carefully control over the arrival rate and sequence of group III atoms and nitrogen radicals onto the sample substrate. By using reflective high energy electron diffraction (RHEED), the change of each layer's surface morphology can be monitored during the growth to achieve the high quality group III-nitride materials.
SELECTIVE MOTION VECTOR PREDICTION METHOD, MOTION ESTIMATION METHOD AND DEVICE THEREOF APPLICABLE TO SCALABLE VIDEO CODING SYSTEM
(2011-10-06)
LI GWO-LONG
;
HUANG HSIAO-SHAN
;
CHANG TIAN-SHEUAN
A selective motion vector prediction method and a motion estimation method and a device thereof applicable to a scalable video coding (SVC) system are disclosed. The selective motion vector prediction method includes the steps of performing an inter prediction to obtain a first motion vector prediction center; performing an inter-layer motion prediction to obtain a second motion vector prediction center; in the case the first and the second motion vector prediction center satisfying a preset condition, using the same reference data to calculate the rate-distortion costs for the inter prediction and the inter-layer motion prediction; and using the rate-distortion costs as a basis to select one of the inter prediction and the inter-layer motion prediction for applying to the SVC system. Thus, the same reference data is shared to enable reduced memory access in the process of coding and accordingly, reduced cost of and power consumption by memory access.
Human microRNA target identification by RRSM
(2011-10-07)
Hsieh, Wan J.
;
Wang, Hsiuying
;
統計學研究所
;
Institute of Statistics
MicroRNAs (miRNAs) are small endogenously expressed non-coding RNAs that regulate target messenger RNAs in various biological processes. In recent years, there have been many studies concentrated on the discovery of new miRNAs and identification of their mRNA targets. Although researchers have identified many miRNAs, few miRNA targets have been identified by actual experimental methods. To expedite the identification of miRNA targets for experimental verification, in the literature approaches based on the sequence or microarray expression analysis have been established to discover the potential miRNA targets. In this study, we focus on the human miRNA target prediction and propose a generalized relative R(2) method (RRSM) to find many high-confidence targets. Many targets have been confirmed from previous studies. The targets for several miRNAs discovered by the HITS-CLIP method in a recent study have also been selected by our study. (C) 2011 Elsevier Ltd. All rights reserved.
Base-Catalyzed Povarov Reaction: An Unusual [1,3] Sigmatropic Rearrangement to Dihydropyrimidobenzimidazoles
(2011-10-07)
Chen, Chih-Hau
;
Yellol, Gorakh S.
;
Lin, Po-Tsung
;
Sun, Chung-Ming
;
應用化學系
A novel base-catalyzed Povarov reaction of arylamines, aldehydes, and electron-deficient dienophiles has been developed. An unprecedented in situ [1,3] sigmatropic rearrangement leading to 4,10-dihydropyrimido[1,2-a]benzimidazoles has also been discovered. An insight of the plausible mechanism is discussed and supported by X-ray crystal study. This cascade reaction is achieved in a one-pot multicomponent fashion on soluble support under microwave conditions.
《非2》婚姻先試了再說
(2011-10-09)
林筱娟
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Department of Communication and Technology
;
傳播與科技學系
《非誠勿擾2》用兩個小時呈現一場人生，模擬了人生必經的分分合合與生老病死。在愛情喜劇中加入死亡的元素，幽默間多了點生命的深度，在笑聲之後，箇中滋味又讓人回味不已，在你還來得及說愛的時候，千萬別錯過……。
原音女孩　《原來如此》
(2011-10-09)
楊依靜
;
Department of Communication and Technology
;
傳播與科技學系
平凡的原音女孩，唱出城市中的不平凡。用音樂說出那些期待被說的話，自然而然地存在日常生活中。
炭火精煉後的美麗結晶
(2011-10-09)
蔡雯琪
;
Department of Communication and Technology
;
傳播與科技學系
「從土胎裡面直接燒出，我的身子、我的骨、我的內在，把最美麗的質地呈現出來。」是陶藝家林瑞華對自己的期許。
我有話要說
(2011-10-09)
吳孟芯
;
Department of Communication and Technology
;
傳播與科技學系
《王者之聲：宣戰時刻 ( The King’s Speech ) 》由真人真事改編，講述二次大戰前夕，英國國王喬治六世克服口吃障礙，並成功發表演說的勵志故事。結合精湛演技與細密的劇情架構，帶領觀眾見證一位王者的誕生。
女人在賽德克巴萊
(2011-10-09)
劉玉蘋
;
Department of Communication and Technology
;
傳播與科技學系
打破大眾對《賽德克巴萊》具有強烈男性意識的既定印象，描寫女性在片中呈現的形象與意識。
《大債時代》　誰能倖免
(2011-10-09)
陳祐元
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Department of Communication and Technology
;
傳播與科技學系
《大債時代》以簡明扼要的文字描寫2008金融海嘯的經過，透過作者幽默流暢的文字，了解經濟危機真正的幕後黑手，以及世界未來的方向。
萬人擁抱盼把愛找回來
(2011-10-09)
張莉雯
;
Department of Communication and Technology
;
傳播與科技學系
當電腦已經可以滿足人們近乎所有的日常需求，人與人之間最親密的交流也跟著漸漸遺失了。為了呼籲大家找回彼此間最親切的距離，中壢市公所二度舉辦「萬人愛擁抱」活動，成功寫下金氏世界紀錄，讓世界看見台灣的愛心。