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Item type:Item, Evolutionary information hidden in a single protein structure(2012-06-01) ;Shih, Chien-Hua ;Chang, Chih-Min ;Lin, Yeong-Shin ;Lo, Wei-ChengHwang, Jenn-KangThe knowledge of conserved sequences in proteins is valuable in identifying functionally or structurally important residues. Generating the conservation profile of a sequence requires aligning families of homologous sequences and having knowledge of their evolutionary relationships. Here, we report that the conservation profile at the residue level can be quantitatively derived from a single protein structure with only backbone information. We found that the reciprocal packing density profiles of protein structures closely resemble their sequence conservation profiles. For a set of 554 nonhomologous enzymes, 74% (408/554) of the proteins have a correlation coefficient > 0.5 between these two profiles. Our results indicate that the three-dimensional structure, instead of being a mere scaffold for positioning amino acid residues, exerts such strong evolutionary constraints on the residues of the protein that its profile of sequence conservation essentially reflects that of its structural characteristics. Proteins 2012;. (c) 2012 Wiley Periodicals, Inc.Item type:Item, Reply to "Comment on using a modified grey relation method for improving airline service quality"(2012-06-01) ;Liou, James J. H. ;Tzeng, Gwo-Hshiung ;Hsu, Chao-Che ;Yeh, Wen-Chien科技管理研究所This is a reply to the comments on the previously published paper entitled "Using a modified grey relation method for improving airline service quality". The commentators question that the paper does not offer any improvement over Chen and Tzeng's (2004) work and uses the same data as in Liou, Tsai, Lin, and Tzeng's (2011b) paper. However, the modified grey relation described therein actually does improve on Chen and Tzeng's (2004) work in two ways. First, the ideal and negative ideal referential sequences are replaced by the aspired to and tolerable levels. Second, the similarity used in the grey relation model is transformed into a weighted gap, "the smaller the better". The same survey data is used in both papers, but the targets and purposes differ. One is focused on economy class passengers, while the other targets all passengers. Therefore, we argue that the comments indicate misunderstanding of the modifications. (C) 2011 Elsevier Ltd. All rights reserved.Item type:Item, Modifying and Reducing Numerical Dissipation in A Two-Dimensional Central-Upwind Scheme(2012-06-01) ;Yu, Chi-Jer ;Liu, Chii-Tung ;應用數學系Department of Applied Mathematics"This study presents a modification of the central-upwind Kurganov scheme for approximating the solution of the 2D Euler equation. The prototype, extended from a 1D model, reduces substantially less dissipation than expected. The problem arises from over-restriction of some slope limiters, which keep slopes between interfaces of cells to be Total-Variation-Diminishing. This study reports the defect and presents a re-derived optimal formula. Numerical experiments highlight the significance of this formula, especially in long-time, large-scale simulations."Item type:Item, A Single-Ended Disturb-Free 9T Subthreshold SRAM With Cross-Point Data-Aware Write Word-Line Structure, Negative Bit-Line, and Adaptive Read Operation Timing Tracing(2012-06-01) ;Tu, Ming-Hsien ;Lin, Jihi-Yu ;Tsai, Ming-Chien ;Lu, Chien-YuLin, Yuh-JiunThis paper presents a novel single-ended disturb-free 9T subthreshold SRAM cell with cross-point data-aware Write word-line structure. The disturb-free feature facilitates bit-inter-leaving architecture, which can reduce multiple-bit upsets in a single word and enhance soft error immunity by employing Error Checking and Correction (ECC) technique. The proposed 9T SRAM cell is demonstrated by a 72 Kb SRAM macro with a Negative Bit-Line (NBL) Write-assist and an adaptive Read operation timing tracing circuit implemented in 65 nm low-leakage CMOS technology. Measured full Read and Write functionality is error free with V-DD down to 0.35 V (similar to 0.15 V lower than the threshold voltage) with 229 KHz frequency and 4.05 mu W power. Data is held down to 0.275 V with 2.29 mu W Standby power. The minimum energy per operation is 4.5 pJ at 0.5 V. The 72 Kb SRAM macro has wide operation range from 1.2 V down to 0.35 V, with operating frequency of around 200 MHz for V-DD around/above 1.0 V.Item type:Item, Ultrasonic vibration-assisted optical glass hot embossing process(2012-06-01) ;Tsai, Yen-Pin ;Hung, Jung-Chung ;Yin, Li-Chao ;Hung, Chinghua機械工程學系A homemade apparatus was used to apply ultrasonic-vibration to assist the glass hot embossing processes. To operate at high temperatures for glass hot embossing, the ultrasonic vibration system was appropriately designed with an embedded cooling system, and an ultrasonic horn was specifically modified for high-temperature use. Molds with both V-groove and Fresnel structures were manufactured for hot embossing experiments on PSK-100 glass. The heights of the molded structures were increased significantly with the assistance of ultrasonic vibration. This technology demonstrates the capability to upgrade the performance of the glass hot embossing process.Item type:Item, Physical properties of amorphous Mo-doped In-Ga-Zn-O films grown by magnetron co-sputtering technique(2012-06-01) ;Liu, Shiu-Jen ;Fang, Hau-Wei ;Hsieh, Jang-Hsing ;Juang, Jenh-Yih材料科學與工程學系Amorphous thin films of In-Ga-Zn-O (a-IGZO) doped with Mo have been fabricated by using magnetron co-sputtering technique. The Mo concentration in a-IGZO films was modulated by varying the sputtering power applied on the Mo target. The electrical, optical and magnetic properties of Mo-doped a-IGZO films grown on glasses were investigated. The carrier density and mobility of a-IGZO films can be remarkably enhanced by low concentration Mo doping. On the other hand, the optical bandgap of a-IGZO films is not significantly affected by Mo doping. However, the transmission is decreased with increasing the Mo doping. Moreover, all Mo-doped films exhibit room-temperature ferromagnetism. (C) 2012 Elsevier Ltd. All rights reserved.Item type:Item, 反稀土廠/核電廠即是反獨裁(國立陽明交通大學出版社, 2012-06-01)李健聰Item type:Item, 運動贊助網路媒合平台理論架構初探(國立交通大學體育室, 2012-06-01) ;林房儹 ;謝承昀 ;Fang-Tsan LinCheng-Yun Hsieh現今企業面臨競爭激烈與資訊爆炸的全球市場,需要一種更有效率的行銷工具。而贊助在近幾年快速成長,成為企業喜愛的行銷工具之一,其中又以運動贊助最廣為使用。本文探討全球贊助現況,並分析我國運動產業以及電子商務之發展。研究指出目前我國運動贊助在事前的媒合,贊助企業與運動組織的連結相當薄弱。因此,提出一個資訊仲介模式應用在運動贊助媒合的網路平台架構理論。由於國內運動產業尚未成熟,由政府訂定的「運動產業發展條例」便成為推動我國運動產業的一大助力。因此,本文將政府以輔導者的角色,納入資訊仲介模式中,發展出全新三方的運動贊助網路媒合平台理論,並在文末提出未來相關研究的方向,希望此理論可以實際應用於產業界,以活絡運動贊助的機會,加速我國運動產業的發展。Item type:Item, 靴帶式驅動電路(2012-06-01) ;何盈杰 ;張家齊蘇朝琴本發明係關於一種能利用其所具有之回授機制來抑制反轉電流以提升其資料傳輸速率,並降低其所消耗之功率的靴帶式驅動電路。其包括:一包含一前端輸入端、一第一反相器、一第二反相器、一第一PMOS電晶體、一第一NMOS電晶體、一第二PMOS電晶體、一第二NMOS電晶體、一第一電容、一第二電容及一前端輸出端的第一級升降壓電路;以及一包含一後端輸入端及一後端輸出端的後端CMOS反相器驅動電路。其中,前端輸出端除了連接至第二PMOS電晶體之汲極與第二NMOS電晶體之汲極以外,更連接至第一PMOS電晶體之閘極與第一NMOS電晶體之閘極,以形成一回授機制抑制反轉電流。Item type:Item, A Path-Connected-Cluster Wireless Sensor Network and Its Formation, Addressing, and Routing Protocols(2012-06-01) ;Tsai, Chia-Hung ;Tseng, Yu-Chee ;資訊工程學系Department of Computer ScienceAlthough wireless sensor networks (WSNs) have been extensively researched, their deployment is still a main concern. We observe that many monitoring applications for WSNs have adopted a path- connected- cluster (PCC) topology, where regions to be monitored are deployed with clusters of sensor nodes. Since these clusters might be physically separated, paths of sensor nodes are used to connect them together. We call such networks PCC-WSNs. PCC-WSNs may be widely applied in real situations, such as bridge-connected islands, street-connected buildings, and pipe-connected ponds. In this paper, we show that the address assignment scheme defined by ZigBee will perform poorly in terms of address utilization. We then propose a systematical solution, which includes network formation, automatic address assignment, and light-weight routing. Simulation results verify the effectiveness of the proposed solution.Item type:Item, On the reliability, consistency, and method-specificity based on the CT-C(M-1) model(2012-06-01) ;Ding, Cherng G. ;Jane, Ten-Der ;經營管理研究所Institute of Business and ManagementIn the present study, we discuss reliability, consistency, and method specificity based on the CT-C(M-1) model, which provides clear definitions of trait and method factors and can facilitate parameter estimation. Properties of the reliability coefficient, the consistency coefficient, and the method-specificity coefficient of the summated score for a trait factor are addressed. The consistency coefficient and the method-specificity coefficient are both functions of the number of items, the average item consistency, and the average item method specificity. The usefulness of the findings is demonstrated in an alternative approach proposed for scale reduction. The approach, taking into account both traits and methods, helps identify the items leading to the maximum of convergent validity or method effects. The approach, illustrated with a simulated data set, is recommended for scale development based on multitrait-multimethod designs.Item type:Item, 新殖民主義論之射程(國立陽明交通大學出版社, 2012-06-01)西川長夫Item type:Item, 數位式線性電壓調變器(2012-06-01) ;謝維致黃威本發明係關於一種可輸出一調變電壓、具有高電流效率及可整合至各式晶片中的數位式線性電壓調變器。其包括:至少一數位誤差偵測電路模組、一第一控制邏輯電路模組、一第二控制邏輯電路模組、一模式指示模組、一分壓器電路模組、至少一上推元件電路模組以及下拉元件電路模組。其中,至少一數位誤差偵測電路模組係依據一介於一比較電壓與一參考電壓之間的電壓差值輸出一邏輯信號,第一控制邏輯電路模組與第二控制邏輯電路模組則分別控制至少一上推元件電路模組及下拉元件電路模組,以輸出前述之調變電壓。Item type:Item, A systematic estimation model for fraction nonconforming of a wafer in semiconductor manufacturing research(2012-06-01) ;Lin, Jun-Shuw ;工業工程與管理學系Department of Industrial Engineering and ManagementThe clustering phenomenon of defects usually occurs in semiconductor manufacturing. However, previous studies did not pay much attention to the influence of clustering phenomenon for estimating fraction nonconforming of a wafer. Thus, this paper presents a systematic estimation model with considering relevant variables about clustering defects for fraction nonconforming of a wafer. The method combines back-propagation neural network (BPNN) with genetic algorithm (GA) to obtain an estimation model. In this study, GA aims to optimize the parameters of BPNN. Five relevant variables: number of defects (ND), squared coefficient of angle variation (SCVA) for defects, squared coefficient of distance variation (SCVD) for defects, defect cluster index (CIM), and the number of cluster groups (NCG) for defects by self-organized map (SOM) are utilized as inputs for GA-BPNN. Finally, a simulation case and a real-world case are used to confirm the effectiveness of proposed method. (C) 2012 Elsevier B. V. All rights reserved.Item type:Item, STATISTICAL PREDICTION OF EMOTIONAL STATES BY PHYSIOLOGICAL SIGNALS WITH MANOVA AND MACHINE LEARNING(2012-06-01) ;Chueh, Tung-Hung ;Chen, Tai-Been ;Lu, Henry Horng-Shing ;Ju, Shan-ShanTao, Teh-HoFor the importance of communication between human and machine interface, it would be valuable to develop an implement which has the ability to recognize emotional states. In this paper, we proposed an approach which can deal with the daily dependence and personal dependence in the data of multiple subjects and samples. 30 features were extracted from the physiological signals of subject for three states of emotion. The physiological signals measured were: electrocardiogram (ECG), skin temperature (SKT) and galvanic skin response (GSR). After removing the daily dependence and personal dependence by the statistical technique of MANOVA, six machine learning methods including Bayesian network learning, naive Bayesian classification, SVM, decision tree of C4.5, Logistic model and K-nearest-neighbor (KNN) were implemented to differentiate the emotional states. The results showed that Logistic model gives the best classification accuracy and the statistical technique of MANOVA can significantly improve the performance of all six machine learning methods in emotion recognition system.Item type:Item, A High-Performance OFDMA PON System Architecture and Medium Access Control(2012-06-01) ;Yuang, Maria C. ;Tien, Po-Lung ;Hsu, Dar-Zu ;Chen, Shing-YuWei, Chia-ChienOrthogonal frequency-division multiplexing (OFDM) passive optical network (PON) has been considered to be a promising next-generation broadband wired access solution. However, based on the current tree-based architecture, existing OFDM PON systems face severe challenges when increasing the scalability and data-rate performance. In this paper, we propose a high-performance virtual-tree orthogonal frequency-division multiple access PON system (VTOPS). With the virtual-tree architecture and coupled with the use of inexpensive direct modulation, VTOPS features high reliability, scalability, spectrum efficiency, and cost effectiveness all at once. For governing the flexible/fair access and dynamic allocation of bandwidth, VTOPS incorporates a rate-based medium access control (MAC) scheme. The MAC scheme performs dynamic rate adjustment using a neural-fuzzy system. By adjusting the system parameters, the MAC scheme can achieve a wide range of delay and fairness performance under a variety of traffic patterns. Finally, we show both theoretical and experimental results to demonstrate that, by applying the power pre-emphasis algorithm and adaptive subchannel modulation, VTOPS achieves 40 Gb/s downlink and 40 Gb/s uplink transmissions, using low-cost 10 GHz directly modulated lasers.Item type:Item, Nitrogen removal from opto-electronic wastewater using the simultaneous partial nitrification, anaerobic ammonium oxidation and denitrification (SNAD) process in sequencing batch reactor(2012-06-01) ;Daverey, Achlesh ;Su, Sin-Han ;Huang, Yu-Tzu ;Lin, Jih-Gaw環境工程研究所Simultaneous partial nitrification, anaerobic ammonium oxidation and denitrification (SNAD) system was applied to treat the opto-electronic industrial wastewater in a 2.5 L sequencing batch reactor. The characteristics of wastewater were low C/N ratio (similar to 0.2) with 100 mg-COD/L and 567 mgNH(4)(+)-N/L. The experiment was carried out over 8 months in six different stages, where nitrogen loading rate was gradually increased from 16 g-N/m(3) d in stage I to 230 g-N/m(3) d in stage VI. The COD and nitrogen removal rates by the SNAD system reached to 28 g COD/m(3) d and 197 g NH4+-N/m(3) d, respectively in stage VI. These results showed that the SNAD system is suitable to treat wastewater containing high nitrogen pollutants with low COD level. Presence of ammonium oxidizing bacteria and anammox bacteria were confirmed by polymerase chain reaction (PCR). PCR results also indicated that Candidatus Kuenenia stuttgartiensis may be one of the dominant species in the reactor. (C) 2011 Elsevier Ltd. All rights reserved.Item type:Item, Applying Genetic Algorithms for Multiradio Wireless Mesh Network Planning(2012-06-01) ;Lin, Ting-Yu ;Hsieh, Kai-Chiuan ;Huang, Hsin-Chun ;電機資訊學士班Undergraduate Honors Program of Electrical Engineering and Computer ScienceTwo main issues that are involved in the performance of multichannel multiradio wireless mesh networks (WMNs) are channel assignment (CA) and multichannel routing (MCR). The joint CA and MCR problem has been proven to be NP-hard. In this paper, we propose to apply genetic algorithms for the CA problem and tackle MCR using linear-programming techniques. Because CA and MCR tend to interact with each other, to reflect such an interplay property, we evaluate the fitness value of a chromosome (certain CA configuration) in our genetic algorithms (GAs) by computing the linear objective function. Therefore, we successfully decouple the two problems and obtain an optimized CA configuration with a corresponding MCR schedule in polynomial time at the WMN planning stage. We demonstrate the detailed genetic evolution processes for three-WMNs with different deployment constraints, which serves as a useful guideline on customizing WMNs under various requirements. Simulation results show that the proposed approach effectively increases the network capacity.Item type:Item, Investigation of the cerebral hemodynamic response function in single blood vessels by functional photoacoustic microscopy(2012-06-01) ;Liao, Lun-De ;Lin, Chin-Teng ;Shih, Yen-Yu I. ;Lai, Hsin-YiZhao, Wan-TingThe specificity of the hemodynamic response function (HRF) is determined spatially by the vascular architecture and temporally by the evolution of hemodynamic changes. Here, we used functional photoacoustic microscopy (fPAM) to investigate single cerebral blood vessels of rats after left forepaw stimulation. In this system, we analyzed the spatiotemporal evolution of the HRFs of the total hemoglobin concentration (HbT), cerebral blood volume (CBV), and hemoglobin oxygen saturation (SO2). Changes in specific cerebral vessels corresponding to various electrical stimulation intensities and durations were bilaterally imaged with 36 x 65-mu m(2) spatial resolution. Stimulation intensities of 1, 2, 6, and 10 mA were applied for periods of 5 or 15 s. Our results show that the relative functional changes in HbT, CBV, and SO2 are highly dependent not only on the intensity of the stimulation, but also on its duration. Additionally, the duration of the stimulation has a strong influence on the spatiotemporal characteristics of the HRF as shorter stimuli elicit responses only in the local vasculature (smaller arterioles), whereas longer stimuli lead to greater vascular supply and drainage. This study suggests that the current fPAM system is reliable for studying relative cerebral hemodynamic changes, as well as for offering new insights into the dynamics of functional cerebral hemodynamic changes in small animals. (C) 2012 Society of Photo-Optical Instrumentation Engineers (SPIE). [ DOI: 10.1117/1.JBO.17.6.061210]Item type:Item, 高中足球教練領導行為之研究(國立交通大學體育室, 2012-06-01) ;蔡玉卿Yu-Ching Tsai目的:本研究主旨在探討高中足球教練領導行為之差異。方法:以修訂後之量表進行問卷調查,研究對象為350位參加100學年度高中足球聯賽之選手,統計方法包括描述性分析、獨立樣本t檢定、單因子變異數分析等。結果:高中足球教練領導行為之訓練與指導行為的程度較高,其次民主行為,而專制行為程度較低。H1、參賽組別對高中足球教練領導行為有顯著差異。H2、個人背景變項內發現接觸足球時間、與教練相處時間及訓練頻率有顯著差異。結論:足球教練應考量組別及個人差異,來選擇運用適當的領導行為提領指導選手,讓選手感覺教練是團隊中精神領袖及心靈導師使團隊中的感覺有像大家庭的情感,進而服從與確實執行教練所交辦之任務,才是球隊獲得勝利的保證。