Browsing by Issue Date, starting with "2012-06-06"

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Protein-Protein Interaction Site Predictions with Three-Dimensional Probability Distributions of Interacting Atoms on Protein Surfaces
(2012-06-06)
Chen, Ching-Tai
;
Peng, Hung-Pin
;
Jian, Jhih-Wei
;
Tsai, Keng-Chang
;
Chang, Jeng-Yih
Protein-protein interactions are key to many biological processes. Computational methodologies devised to predict protein-protein interaction (PPI) sites on protein surfaces are important tools in providing insights into the biological functions of proteins and in developing therapeutics targeting the protein-protein interaction sites. One of the general features of PPI sites is that the core regions from the two interacting protein surfaces are complementary to each other, similar to the interior of proteins in packing density and in the physicochemical nature of the amino acid composition. In this work, we simulated the physicochemical complementarities by constructing three-dimensional probability density maps of non-covalent interacting atoms on the protein surfaces. The interacting probabilities were derived from the interior of known structures. Machine learning algorithms were applied to learn the characteristic patterns of the probability density maps specific to the PPI sites. The trained predictors for PPI sites were cross-validated with the training cases (consisting of 432 proteins) and were tested on an independent dataset (consisting of 142 proteins). The residue-based Matthews correlation coefficient for the independent test set was 0.423; the accuracy, precision, sensitivity, specificity were 0.753, 0.519, 0.677, and 0.779 respectively. The benchmark results indicate that the optimized machine learning models are among the best predictors in identifying PPI sites on protein surfaces. In particular, the PPI site prediction accuracy increases with increasing size of the PPI site and with increasing hydrophobicity in amino acid composition of the PPI interface; the core interface regions are more likely to be recognized with high prediction confidence. The results indicate that the physicochemical complementarity patterns on protein surfaces are important determinants in PPIs, and a substantial portion of the PPI sites can be predicted correctly with the physicochemical complementarity features based on the non-covalent interaction data derived from protein interiors.
Dipole coupling effect of holographic fermion in charged dilatonic gravity
(2012-06-06)
Wen, Wen-Yu
;
Wu, Shang-Yu
;
物理研究所
;
Institute of Physics
In this Letter, we study the dipole coupling effect of holographic fermion in a charged dilatonic black hole proposed by Gubser and Rocha (2010) [1]. It is found that the property of Fermi liquid is rigid under perturbation of dipole coupling, and the Fermi momentum is linearly shifted. A gap is dynamically generated as the coupling becomes large enough and the Fermi surface ceases to exist as the bulk dipole coupling further increases. (C) 2012 Elsevier B.V. All rights reserved.
「無畸不美」：波特萊爾的《惡之華》
(2012-06-06)
趙順良
;
Open Education Office
;
開放教育推動中心
課程首頁本課程是由交通大學新文藝復興閱讀計畫提供。 96 年 8 月當各大學紛紛摩拳擦掌準備迎接新生的同時，交通大學校長吳重雨則因為一則來自於七月份泰晤士報，有關於英國首相布朗公布其夏日讀書清單的新聞中，看到了他對知識的尊重。在這同時，吳重雨校長也思考著，要如何為學生準備追求知識的環境和激發他們對知識的尊重與喜愛。台積電張忠謀董事長曾陳述他 18 歲進入哈佛那一年，博覽文史哲理工經典群籍，至此奠定了他求知的基礎，並借海明威名言，將其改為「哈佛這一年為人生可帶走的盛宴。」吳重雨校長以張董事長的學習為借鏡，認為學生固然能藉由自我閱讀的方式學習到豐沛的知識，但透過名人、大師親臨現場地介紹經典書籍，更能加深學子們對於書籍的認識與興趣，這也是「新文藝復興閱讀計劃」 ( 以下簡稱 : 「經典名著選讀」 ) 活動展開籌劃的緣由。於是，吳重雨校長便積極敦請「交大通識教育委員會」，接手籌備本計劃的相關活動，而該中心也成為實際施行本計畫的策動、開課以及認證單位。至此，期許交大學子藉由閱讀、聽講來提昇人文素養、開拓視野的「新文藝復興閱讀計劃」，就此展開。
METHOD OF FORMING SINGLE-LAYER PHOTONIC CRYSTAL STRUCTURE
(2012-06-07)
Wu Pu-Wei
;
Huang Yi-Jui
A method of forming a single-layer photonic crystal structure. The method includes depositing electrophoretic suspension, working electrode and lower electrode in a container, wherein the working electrode and the lower electrode are formed at upper and lower parts of the container, respectively, and spaced apart at an distance; and applying an electric voltage to the working electrode and the lower electrode to form an electric field, such that particles in the electrophoretic suspension form a single-layer photonic crystal structure on the working electrode under interactive actions of the electric field and a gravity field by an electrophoresis self-assembly technique. Therefore, the single-layer photonic crystal structure has a low cost, and good quality and recurring property.
LIQUID CRYSTAL LENS STRUCTURE AND METHOD OF DRIVING SAME
(2012-06-07)
LIN YI-HSIN
;
LIN HUNG-CHUN
A liquid crystal (LC) lens structure and a method of driving same are disclosed. The LC lens structure includes an upper substrate, a lower substrate, a liquid crystal and polymer composite film, and an LC layer. The upper substrate is provided with a first conducive layer and a first alignment layer; and the lower substrate is provided with a second conductive layer and a second alignment layer. The liquid crystal and polymer composite film is arranged at one side of the first alignment layer to form a first lens, and the LC layer is arranged between the liquid crystal and polymer composite film and the second alignment layer to form a second lens. By building the liquid crystal and polymer composite film in the LC lens structure, it is able to realize an LC lens with low operating voltage and large focusing range.
PHOTONIC CRYSTAL AND METHOD OF FABRICATING THE SAME
(2012-06-07)
Wu Pu-Wei
;
Huang Yi-Jui
;
Lai Chun-Han
A three-dimensional geometric photonic crystal and a method of fabricating the photonic crystal are disclosed. The photonic crystal includes a geometric structure having a plurality of electrophoretic self-assembled particles and the plurality of particles are periodically arranged at any cross sections of the geometric structure. The method includes preparing an electrophoresis deposition suspension, installing first and second electrodes in the electrophoresis deposition suspension with the first electrode being encircled by the second electrode, and applying a voltage to the first electrode and the second electrode to form an electric field between the first and second electrodes, such that particles in the electrophoresis deposition suspension are electrophoretic self-assembled, and a periodically arranged geometric structure is formed. A photonic crystal thus may have a three-dimensional geometric structure in any shape.
Moment method analysis of plane wave scattering from planar corrugated surfaces using parallel-plate cavity Green's functions and derivation of analytic reflection-phase formulas for both polarizations and oblique azimuth planes
(2012-06-07)
Kehn, M. Ng Mou
;
電信工程研究所
;
Institute of Communications Engineering
A rigorous but yet highly accurate and efficient numerical treatment of plane wave scattering by T-shaped planar corrugations through full-wave modal analysis is first presented in this paper, which entails the moment method using parallel-plate waveguide cavity Green's functions and a numerical spectral-domain Green's function for planar stratified media. Investigations in terms of both reflection-phase and dispersion diagrams are conducted. After validating with the commercial software package: CST Microwave Studio, this moment-method is in turn used to verify a formula derived by the transverse resonance technique (TRT) for the surface-wave propagation constant of corrugations in terms of the dispersion diagram. Correspondences between the reflection-phase and dispersion diagrams are then established by relating the high and low impedance frequencies in the former with the pass and stop bands of the latter. With the abovementioned formula, the way is paved for a novel derivation of explicit formulas for the reflection-phase of an incident plane wave impingent on the corrugations as closed-form analytic functions of the various parameters, even for oblique azimuth planes of incidence and for both TE and TM polarizations. Doing so, the high or low surface-impedance (AMC or AEC) properties of such corrugations can virtually be acquired instantly, thus providing incomparable speedup of the process of thorough reflection-phase characterization of AMC or high-impedance surfaces and soft surfaces, thus affording rapid designs of antennas and microwave devices that make use of them.
Effects of Porphyrinic meso-Substituents on the Photovoltaic Performance of Dye-Sensitized Solar Cells: Number and Position of p-Carboxyphenyl and Thienyl Groups on Zinc Porphyrins
(2012-06-07)
Ambre, Ram
;
Chen, Kwan-Bo
;
Yao, Ching-Fa
;
Luo, Liyang
;
Diau, Eric Wei-Guang
In order to understand the effects of meso-substituents of the zinc porphyrins on optical, electrochemical, and photovoltaic properties, a series of porphyrins with different combinations of thienyl (S) and p-carboxyphenyl (A) groups as the meso substituents have been systematically synthesized and studied. The properties of zinc complexes 3S1A, trans-2S2A, cis-2S2A, and 1S3A were fully investigated by absorption and emission spectra, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectra, density functional theory (DFT) calculations, electrochemical, photophysical, and photovoltaic measurements. With the increasing number of meso-thienyl groups, slight red-shifts of Soret and Q bands were observed in both absorption and emission spectra. All of the absorption spectra of zinc porphyrins on TiO2 film show broadening and splitting of Soret bands because of excitonic coupling of porphyrins. ATR-FTIR spectra revealed likely modes to determine either a single arm (in 3S1A and trans-2S2A) or double arms (in 1S3A and cis-2S2A) attached on TiO2. Two factors of p-carboxyphenyl and thienyl groups affecting the devices performance-heavy atom effect and the amount of dye loading on TiO2-are concluded. Overall, the power conversion efficiencies (eta) of the devices exhibit the following order: 1S3A (3.0%) > cis-2S2A (2.5%) > trans-2S2A (1.8%) >> 3S1A (0.2%).
Nonvolatile floating gate memory containing AgInSbTe-SiO2 nanocomposite layer and capping the HfO2/SiO2 composite blocking oxide layer
(2012-06-08)
Chiang, Kuo-Chang
;
Hsieh, Tsung-Eong
;
材料科學與工程學系
;
Department of Materials Science and Engineering
An extremely large memory window shift of about 30.7 V and high charge storage density = 2.3 x 10(13) cm(-2) at +/- 23 V gate voltage sweep were achieved in the nonvolatile floating gate memory (NFGM) device containing the AgInSbTe (AIST)-SiO2 nanocomposite as the charge trap layer and HfO2/SiO2 as the blocking oxide layer. Due to the deep trap sites formed by high-density AIST nanocrystals (NCs) in the nanocomposite matrix and the high-barrier-height feature of the composite blocking oxide layer, a good retention property of the device with a charge loss of about 16.1% at +/- 15 V gate voltage stress for 10(4) s at the test temperature of 85 degrees C was observed. In addition to inhibiting the Hf diffusion into the programming layer, incorporation of the SiO2 layer prepared by plasma-enhanced chemical vapor deposition in the sample provided a good Coulomb blockade effect and allowed significant charge storage in AIST NCs. Analytical results demonstrated the feasibility of an AIST-SiO2 nanocomposite layer in memory device fabrication with a simplified processing method and post-annealing at a comparatively low temperature of 400 degrees C in comparison with previous NC-based NFGM studies.
道士資格無法管　民眾難辨
(2012-06-10)
曾意倫
;
Department of Communication and Technology
;
傳播與科技學系
所謂道士，是學道之人的泛稱，道士信奉道教教義，並以從事道教活動為職業。然而台灣社會尊重信仰自由，政府並未制定宗教法等相關規範，也因此一般民眾無法判定道士是否具有真才實料，甚至無法分辨真假道士。
寶藏巖　藝居尋共生　
(2012-06-10)
楊佳靜
;
Department of Communication and Technology
;
傳播與科技學系
寶藏巖聚落自注入藝居共生的概念後，成為台北市的文創景點。但寶藏巖成立初期卻因制度設計不健全，藝術家與居民的溝通產生阻礙，藝術與公共性之間也漸有失衡的傾向，成為寶藏巖共生聚落目前首要反思的課題。
藝文校園　交大新生命
(2012-06-10)
林儀
;
Department of Communication and Technology
;
傳播與科技學系
國立交通大學以理工科見長，在台灣產業界具有一定的領導地位。交大學生功課重，很多時間都拿來讀書了，似乎比較少有接觸藝文訊息的習慣，但這種情形在最近幾年有了極大的改變。
我的變胖日記
(2012-06-10)
李安媞
;
Department of Communication and Technology
;
傳播與科技學系
很多人都想要瘦身，很羨慕那些有目標又有自制力的人，可以為了減肥讓自己不吃甜的東西。我覺得我真的應該好好跟他們學習。
激情之後　後奧運效應
(2012-06-10)
李彥璋
;
Department of Communication and Technology
;
傳播與科技學系
倫敦奧運即將到來，必定吸引成千上萬的觀光客前往，但在奧運會後如何能夠避免「後奧運效應」也是一大難題。
草地小廚房　進攻校園
(2012-06-10)
蘇冠心
;
Department of Communication and Technology
;
傳播與科技學系
為鼓勵年輕人親自下廚，一群愛烹飪的台大生突發奇想，舉辦草地野餐式的廚藝競賽，由參賽者提供創意餐點，讓校園外食族能夠吃得健康，進而嘗試自己動手做。他們做創意料理，也展現年輕人追求簡單生活的態度。
兩岸軍備知多少
(2012-06-10)
胡哲揚
;
Department of Communication and Technology
;
傳播與科技學系
兩岸交流正頻繁，但是若哪天對岸不再友善，雙方的軍備落差到底會是平等競賽，又或將有重大懸殊？
總編輯的話
(2012-06-10)
吳孟芯
;
Department of Communication and Technology
;
傳播與科技學系
本週來到喀報的一百四十期，辛苦傳科系102級同學依舊努力不懈，堅持到現在。本期發稿量共二十四篇，以十一篇影像作品佔本期類目最多數，另有廣播、動畫Flash和文字作品的呈現。
不間斷的人生賽道　徐瑞德
(2012-06-10)
許雅筑
;
Department of Communication and Technology
;
傳播與科技學系
徐瑞德除了帶領大甲高中自由車隊之外，也是職業自由車隊前勁隊的總教練。徐瑞德在孕育選手方面不遺餘力，而他心中懷著一個職業化的夢。
公益彩券知多少
(2012-06-10)
楊依靜
;
Department of Communication and Technology
;
傳播與科技學系
我們現在所熟知的彩券，在中國古代時就以「彩票」存在。而公益彩券發行的目的，就是為了提升社會福利，並促進弱勢就業，因此，法規都有明訂公益彩券的餘額該如何分配，以及保障身心障礙者就業的權益。
金融海嘯　電子業衰退隱憂
(2012-06-10)
陳祐元
;
Department of Communication and Technology
;
傳播與科技學系
雖然金融海嘯已經過四年，但是它的影響並未衰退，反而引發許多後續事件。素來以理工科系聞名的交通大學特地舉辦多場財經論壇，說明後金融危機下台灣電子業的前景，希望激起學生的好奇心以及危機感。