Browsing by Issue Date, starting with "2013-11-14"

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Theoretical Formulation and Simulation of Electronic Sum-Frequency Generation Spectroscopy
(2013-11-14)
Lin, Chih-Kai
;
Hayashi, Michitoshi
;
Lin, Sheng Hsien
;
應用化學系
;
Department of Applied Chemistry
Sum-frequency generation (SFG) spectroscopy is a powerful tool for not only identifying molecular species but also analyzing orientation configurations on a surface/interface. In this Article, we presented reformulation of the theoretical framework of electronic SFG spectroscopy, the signal of which could be greatly enhanced by tuning one or two incident beam frequencies resonant with electronic excited states. Simulated electronic SFG spectra resonant at the sum frequency of a pair of coumarin-derivative pH-indicator surfactant molecules, 4-methyl-7-hydroxycoumarin and its anionic counterpart (MHC/MHC-), floating on the water surface were carried out as a demonstration.
EMBEDDED INDUSTRIAL CONTROLLER WITH BICYCLE FRAME SHAPE
(2013-11-14)
Tseng Yung-Sheng
;
Shih Ching-Wei
;
Jeng Shyr-Long
;
Chang Edward-Yi
;
Chang Chia-Hua
An embedded industrial controller with a bicycle frame shape is disclosed. The embedded industrial controller includes a casing with the bicycle frame shape having an upper tube, a lower tube, a front fork, a rear lower fork, a rear upper fork and a base tube, a motherboard, a battery module, a power electrical port and a plurality of input and output electrical ports. The embedded industrial controller with a bicycle frame shape of the present invention has significantly improved functions than the conventional industrial controller, and further meets the conventional requirements such as dust proof, vibration proof, and heat dissipation.
INTERACTIVE VIDEO PLATFORM SYSTEM AND METHOD FOR THE SAME
(2013-11-14)
FU HSIN-CHIA
;
TSENG CHENG-LUNG
;
TAI YUNG-CHANG
;
LIN JIN SHENG
;
LEE YI-JUI
The present invention provides an interactive video platform system and a method for the same. Users at the client terminals link to the interactive video platform via a browser to participate in video interactivities among the users. The present invention also provides a virtual camera and a virtual transparency to promote the convenience of the users and the quality and efficiency of the interactive video platform system. At the end of video interactivities, a video server of the interactive video platform system edits the information of the video interactivity and stores the information in a central database for reference by users.
LIGAND AND METAL COMPLEX HAVING THE SAME
(2013-11-14)
Wang Yun-Ming
;
Liu Gin-Chung
;
Chen Chiao-Yun
;
Li Teng-Wen
A ligand and a metal complex having the ligand are provided. The ligand and a paramagnetic metal ion form a metal complex with high stability, high relaxivity and high biocompatibility. The metal complex of the present invention is applicable to the preparation of MRI contrast agents for detecting atherosclerosis. The MRI contrast agent includes a peptide sequence specific to a matrix metalloprotease, and can be recognized by a pathological thrombocyte to target a specific site, so as to enhance the imaging contrast.
Electric connecting structure comprising preferred oriented Cu6Sn5 grains and method for fabricating the same
(2013-11-14)
CHEN Chih
;
LIN Han-Wen
An electric connecting structure comprising preferred oriented Cu6Sn5 grains and a method for fabricating the same are disclosed. The method of the present invention comprises steps: (A) providing a first substrate; (B) forming a first nano-twinned copper layer on part of a surface of the first substrate; (C) using a solder to connect the first substrate with a second substrate having a second electrical pad, in which the second electrical pad comprises a second nano-twinned copper layer, and the solder locates between the first nano-twinned copper layer and the second nano-twinned copper layer; and (D) reflowing at the temperature of 200° C. to 300° C. to transform at least part of the solder into an intermetallic compound (IMC) layer, in which the IMC layer comprises plural Cu6Sn5 grains with a preferred orientation; wherein at least 50% in volume of the first and second nano-twinned copper layer comprises plural grains.
Vibrational Energy Flow between Modes by Dynamic Mode Coupling in THIATS J-Aggregates
(2013-11-14)
Hasegawa, Daisuke
;
Nakata, Kazuaki
;
Tokunaga, Eiji
;
Okamura, Kotaro
;
Du, Juan
We performed ultrafast pump-probe spectroscopy of J-aggregates of 3,3'-disulfopropyl-5,5'-dichloro-9-ethyl thiacarbocyanine triethylammonium (THIATS), one of the most typical cyanine dyes, and detected excited molecular vibrations, using a sub-10 fs pulse laser. The time-resolved two-dimensional difference absorption (Delta A) spectra are observed between -314 and 1267 fs. By performing the Fourier transform and spectrogram analysis, vibrational modes in THIATS are observed at 285, 485, 555, 824, and 1633 cm(-1) and there was a modulation of the vibrational frequencies around 1633 cm(-1) which depend on the delay time, respectively. By the analysis of the modulation, energy flow is found to take place from other modes to the 1633 cm(-1) mode through the low frequency mode with similar to 50 cm(-1). Also, by fitting the real-time traces of Delta A with the sum of two exponential functions and a constant term, the average lifetimes of three electronically excited states were found to be tau(1) = 52 +/- 5 fs and tau(2) = 540 +/- 78 fs. By performing single-exponential fitting around the stationary absorption peak at 1.990 eV, in the negative time range, the electronic dephasing time, T-2(ele), is determined to be 18.30 fs.
Deciphering the Catalysis-Associated Conformational Changes of Human Adenylate Kinase 1 with Single-Molecule Spectroscopy
(2013-11-14)
Lin, Chien Y.
;
Huang, Jung Y.
;
Lo, Leu-Wei
;
光電工程學系
;
Department of Photonics
Human adenylate kinase isoenzyme 1 (AK1) is the key enzyme in maintaining the cellular energy homeostasis. The catalysis-associated conformational changes of AK1 involve large-amplitude rearrangements. To decipher the conformational changes of AK1 at the single-molecule level, we tagged AK1 with two identical fluorophores, one near the substrate-binding site and the other at the boundary of the core domain. We found that magnesium ion binding to AK1 increases the structural heterogeneity of AK1, whereas ADP binding reduces the structural heterogeneity. We exploited the hidden Markov model to extract the underlying catalysis-associated conformational dynamics and determined thermodynamic parameters of the multiple catalytic pathways. The third-order correlation difference calculated from photon fluctuation traces reveals the irreversible nature of the conformational motions, suggesting that single-molecule AK1 is in a nonequilibrium steady state. This discovery offers a fresh viewpoint to look into the molecular mechanisms of cellular biochemistry.
Words with a generalized restricted growth property
(2013-11-15)
Fuchs, Michael
;
Prodinger, Helmut
;
應用數學系
;
Department of Applied Mathematics
Words where each new letter (natural number) can never be too large, compared to the ones that were seen already, are enumerated. The letters follow the geometric distribution. Also, the maximal letter in such words is studied. The asymptotic answers involve small periodic oscillations. The methods include a chain of techniques: exponential generating function, Poisson generating function, Mellin transform, depoissonization. (C) 2012 Royal Dutch Mathematical Society (KWG). Published by Elsevier B.V. All rights reserved.
Growth of optical-quality, uniform In-rich InGaN films using two-heater metal-organic chemical vapor deposition
(2013-11-15)
Fu, S. F.
;
Chen, C. Y.
;
Li, F. W.
;
Hsu, C. H.
;
Chou, W. C.
Good-optical-quality, thick InxGa1-xN films with high In content were grown using a homemade two-heater metal-organic chemical vapor deposition system. By varying the growth temperature, it was Found that the In composition of the InGaN epilayer varied from 18 to 59% as the substrate temperature decreased from 750 to 625 degrees C. Our results show that the optical properties in terms of the emission peak wavelength and linewidth are uniformly distributed throughout the entire 2 in. wafer for the x=0.40 InGaN sample. The resultant mean peak wavelength and FWHM are 808 +/- 6 nm and 229 +/- 18 meV, respectively, at 18 K. In addition, for the InGaN film grown at 625 degrees C, a noticeable decrease in the In composition occurred when the ceiling temperature was >800 degrees C, indicative of the occurrence of parasitic reactions in the gas phase. (C) 2013 Elsevier B.V. All rights reserved.
A compact biological cell irradiation system with a Van de Graaff accelerator
(2013-11-15)
Cho, I. C.
;
Niu, H.
;
Chen, C. H.
;
Chou, W. T.
;
Yu, Y. C.
This report describes the development of a compact microcell irradiation system in the 3 MV MN Van de Graaff accelerator in the Accelerator Laboratory of National Tsing Hua University (NTHU). The main feature of this system is backscattering, a technique whereby a 100 nm gold scattering foil is placed in the center of a scattering chamber, instead of a 90 bending magnet. The incident particles produced by the accelerator bombard the scattering foil and scatter isotropically. A set of micro pinholes was installed above the scattering foil and directed the 90 scattering particles to irradiate the cell target. This innovation simplifies the system design and massively reduces the cost and space requirements for system construction. (C) 2013 Elsevier B.V. All rights reserved.
Design and demonstration of high quality-factor H1-cavity in two-dimensional photonic crystal
(2013-11-15)
Fu, Ying-Jhe
;
Lee, Yi-Shan
;
Lin, Sheng-Di
;
電子工程學系及電子研究所
;
Department of Electronics Engineering and Institute of Electronics
We introduce a method for designing an H1 photonic crystal cavity to enhance its quality factor (Q factor). The highest theoretical Q factor of 120,000 is obtained. The Fourier transformation of field distribution shows that the enhancement arises from the component reduction of a leaky mode. The Q-factor improvement has also been demonstrated experimentally with the highest value of 11,700. Our design could be useful for studying light-matter interaction in an H1 cavity as the mode volume only increases slightly. (C) 2013 Optical Society of America
New TDR waveguides and data reduction method for monitoring of stream and drainage stage
(2013-11-15)
Chung, Chih-Chung
;
Lin, Chih-Ping
;
Wu, I. -Ling
;
Chen, Ping-Hung
;
Tsay, Ting-Kuei
Less known in the field of hydrological measurements in civil engineering, time domain reflectometry (TDR) has been developed as a new solution to some of the more difficult level measurement problems. This study applied TDR methodology to provide two new designs for a water level sensing waveguide that can be applied in difficult field conditions such as in an underpass, tunnel, culvert, or sewer, etc. Two types of water level sensing waveguides are presented, including a rigid assembled coaxial pipe and a flexible adhered parallel wire. The corresponding data reduction procedure is also proposed to account for uncertainty of travel time analysis and calibrate the velocity of pulse propagation along the waveguides. The satisfactory performance of both the proposed TDR waveguides and data reduction method was experimentally validated. A field case study further demonstrated the feasibility of the TDR technique for water level measurements under typical urban drainage conditions. (C) 2013 Elsevier B.V. All rights reserved.
Thermoelectric properties of bismuth-selenide films with controlled morphology and texture grown using pulsed laser deposition
(2013-11-15)
Phuoc Huu Le
;
Liao, Chien-Neng
;
Luo, Chih Wei
;
Lin, Jiunn-Yuan
;
Leu, Jihperng
Polycrystalline, thermoelectric thin films of bismuth selenide (Bi2Se3) were grown on SiO2/Si (1 1 1) substrates, using pulsed laser deposition (PLD). Bi2Se3 films with highly c-axis-oriented and controlled textures were fabricated by maintaining the helium gas pressure (P) between 0.7 and 173 Pa and the substrate temperature (T-s) between 200 and 350 degrees C. The carrier concentration (n) of films decreased with increasing P, which was attributed to the increase of Se concentration from Se deficiency (P <= 6.7 Pa) to stoichiometry to slight Se enrichment (P >= 40 Pa). The Seebeck coefficient (S) was enhanced considerably because of the reduction in n, following the S similar to n(-2/3) relation approximately. The average grain size increased from approximately 100 to 500 nm when T-s was raised from 200 to 350 degrees C, resulting in enhanced carrier mobility (mu) and electrical conductivity (sigma) and a reduced full width at half maximum of (0 0 6) peaks. The shape of grains transformed from rice-like at T-s of 200-250 degrees C to layered-hexagonal platelets (L-HPs) or super-layered flakes (S-LFs) at T-s of 300-350 degrees C. Films that were grown at 300 degrees C and 40 Pa and contained highly c-axis oriented L-HPs possessed the highest power factor (PF =S-2 sigma), which reached 5.54 mu W cm(-1) K-2, where S=75.8 mu V/K and sigma = 963.8 S cm(-1). (C) 2013 Elsevier B.V. All rights reserved.
Incorporating customer satisfaction into the decision-making process of product configuration: a fuzzy Kano perspective
(2013-11-15)
Wang, Chih-Hsuan
;
工業工程與管理學系
;
Department of Industrial Engineering and Management
In an era of global customisation, buyers continuously benefit from the flexibility of selecting their desired options when making decisions on purchasing. Most manufacturing companies, however, need to balance the trade-offs between enhancing product variety and controlling manufacturing cost. In order to fulfil the goal of market-oriented product development, customer satisfaction needs to be well incorporated into the decision-making process of product configuration. Therefore, a hybrid framework is presented to address two critical issues in new product development: customer satisfaction and product configuration. In the beginning, fuzzy Kano model is employed to elicit customer perception of product attributes and extract customer satisfaction. Consecutively, information entropy is used for deriving the important weights of product attributes. Lastly, by means of Technique for Order Preference by Similarity to Ideal Solution, competing design alternatives are efficiently prioritised and configured. In particular, a case study on configuring varieties of smart pads is demonstrated to justify the validity of the proposed framework. With consideration of and the pricing policies of multi-segments, a systematic framework to effectively bridge customer satisfaction and product configuration is offered for the academics and industrial practitioners.
Conjugation of Benzylvanillin and Benzimidazole Structure Improves DNA Binding with Enhanced Antileukemic Properties
(2013-11-15)
Al-Mudaris, Zena A.
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Majid, Aman S. A.
;
Ji, Dan
;
Al-Mudarris, Ban A.
;
Chen, Shih-Hsun
Benzyl-o-vanillin and benzimidazole nucleus serve as important pharmacophore in drug discovery. The benzyl vanillin (2-(benzyloxy)-3-methoxybenzaldehyde) compound shows anti-proliferative activity in HL60 leukemia cancer cells and can effect cell cycle progression at G2/M phase. Its apoptosis activity was due to disruption of mitochondrial functioning. In this study, we have studied a series of compounds consisting of benzyl vanillin and benzimidazole structures. We hypothesize that by fusing these two structures we can produce compounds that have better anticancer activity with improved specificity particularly towards the leukemia cell line. Here we explored the anticancer activity of three compounds namely 2-(2-benzyloxy-3-methoxyphenyl)-1H-benzimidazole, 2MP, N-1-(2-benzyloxy-3-methoxybenzyl)-2-(2-benzyloxy-3-methoxyphenyl)-1H-benzimidazole, 2XP, and (R) and (S)-1-(2-benzyloxy-3-methoxyphenyl)-2, 2, 2-trichloroethyl benzenesulfonate, 3BS and compared their activity to 2-benzyloxy-3-methoxybenzaldehyde, (Bn1), the parent compound. 2XP and 3BS induces cell death of U937 leukemic cell line through DNA fragmentation that lead to the intrinsic caspase 9 activation. DNA binding study primarily by the equilibrium binding titration assay followed by the Viscosity study reveal the DNA binding through groove region with intrinsic binding constant 7.39 mu M/bp and 6.86 mu M/bp for 3BS and 2XP respectively. 2XP and 3BS showed strong DNA binding activity by the UV titration method with the computational drug modeling showed that both 2XP and 3BS failed to form any electrostatic linkages except via hydrophobic interaction through the minor groove region of the nucleic acid. The benzylvanillin alone (Bn1) has weak anticancer activity even after it was combined with the benzimidazole (2MP), but after addition of another benzylvanillin structure (2XP), stronger activity was observed. Also, the combination of benzylvanillin with benzenesulfonate (3BS) significantly improved the anticancer activity of Bn1. The present study provides a new insight of benzyl vanillin derivatives as potential anti-leukemic agent.
Efficient numerical methods for computing ground states of spin-1 Bose-Einstein condensates based on their characterizations
(2013-11-15)
Bao, Weizhu
;
Chern, I-Liang
;
Zhang, Yanzhi
;
應用數學系
;
數學建模與科學計算所(含中心)
In this paper, we propose efficient numerical methods for computing ground states of spin-1 Bose-Einstein condensates (BECs) with/without the Ioffe-Pritchard magnetic field B (X). When B (X) not equal 0, a numerical method is introduced to compute the ground states and it is also applied to study properties of ground states. Numerical results suggest that the densities of m(F) = +/- 1 components in ground states are identical for any nonzero B(x). In particular, if B(x) B not equal 0 is a constant, the ground states satisfy the single-mode approximation. When B(x) 0, efficient and simpler numerical methods are presented to solve the ground states of spin-1 BECs based on their ferromagnetic/antiferromagnetic characterizations. Numerical simulations show that our methods are more efficient than those in the literature. In addition, some conjectures are made from our numerical observations. (C) 2013 Elsevier Inc. All rights reserved.
Biscalix[4]arene Derivative As a Very Efficient Phase Selective Gelator for Oil Spill Recovery
(2013-11-15)
Tsai, Chia-Chen
;
Cheng, Ying-Tsai
;
Shen, Li-Ching
;
Chang, Kai-Chi
;
Ho, I-Ting
A biscalixarene framework, without long alkyl chains, has been readily synthesized in three steps starting from the parent calix[4]arene. The biscalix[4]arene 1 was able to form organogels in various alcoholic solvents; furthermore, it exhibited an excellent phase selective gelation property that is potentially useful in oil spill recovery.
追日裝置
(2013-11-16)
謝侑龍
;
張翼
;
鄭時龍
;
成維華
;
呂秉翰
一種追日裝置，包括基座、設於該基座上之第一傳動器、第二傳動器與支柱、樞接於該支柱以承載太陽能發電模組之承載座、樞接該第一傳動器與該承載座之第一支撐桿以及樞接該第二傳動器與該承載座之第二支撐桿。本發明具有高結構剛性及高承載能力，除可抗強風外，尚具有高追蹤精度及較大的旋轉角度，使太陽能板能準確且長時間地對準太陽，因此可大幅提升太陽能發電模組之效能。
具自行車架外形之嵌入式工業控制器
(2013-11-16)
曾詠勝
;
施境瑋
;
鄭時龍
;
張翼
;
張嘉華
一種具自行車架外形之嵌入式工業控制器，包括由上管、下管、前叉、後下叉、後上叉以及座管所形成之具有自行車架外形之機殼、主機板、電池模組、電源電氣埠以及複數訊號輸入及輸出電氣埠。本發明之具自行車架外形之嵌入式工業控制器不僅考慮了習知技術中機殼對防塵防震、散熱以及外型美感之要求，更可結合輪圈、輪胎、坐墊、把手、踏板以及齒輪傳動裝置等自行車配件，以成為具有邏輯控制，時序控制及模擬控制等各種控制功能之自行車。
微型顯微鏡及其光學元件的製作方法
(2013-11-16)
孫慶成
;
余業緯
;
鄭智元
一種用於微型顯微鏡的光學元件的製作方法包括使一訊號光及一參考光入射至一光學材料；訊號光與參考光干涉使光學材料上形成複數光柵。本發明亦揭露一種微型顯微鏡。