Browsing by Issue Date, starting with "2013-11-28"
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Item type:Item, Reduction of defect formation in amorphous indium-gallium-zinc-oxide thin film transistors by N2O plasma treatment(2013-11-28) ;Jhu, Jhe-Ciou ;Chang, Ting-Chang ;Chang, Geng-Wei ;Tai, Ya-HsiangTsai, Wu-WeiAn abnormal sub-threshold leakage current is observed at high temperature in amorphous indium-gallium-zinc-oxide thin film transistors (a-IGZO TFTs). This phenomenon occurs due to a reduced number of defects in the device's a-IGZO active layer after the device has undergone N2O plasma treatment. Experimental verification shows that the N2O plasma treatment enhances the thin film bonding strength, thereby suppressing the formation of temperature-dependent holes, which are generated above 400 K by oxygen atoms leaving their original sites. The N2O plasma treatment devices have better stability performance than as-fabricated devices. The results suggest that the density of defects for a-IGZO TFTs with N2O plasma treatment is much lower than that in as-fabricated devices. The N2O plasma treatment repairs the defects and suppresses temperature-dependent sub-threshold leakage current. (C) 2013 AIP Publishing LLC.Item type:Item, Instantaneous normal mode analysis for intermolecular and intramolecular vibrations of water from atomic point of view(2013-11-28) ;Chen, Yu-Chun ;Tang, Ping-Han ;Wu, Ten-Ming ;物理研究所Institute of PhysicsBy exploiting the instantaneous normal mode (INM) analysis for models of flexible molecules, we investigate intermolecular and intramolecular vibrations of water from the atomic point of view. With two flexible SPC/E models, our investigations include three aspects about their INM spectra, which are separated into the unstable, intermolecular, bending, and stretching bands. First, the O- and H-atom contributions in the four INM bands are calculated and their stable INM spectra are compared with the power spectra of the atomic velocity autocorrelation functions. The unstable and intermolecular bands of the flexible models are also compared with those of the SPC/E model of rigid molecules. Second, we formulate the inverse participation ratio (IPR) of the INMs, respectively, for the O- and H-atom and molecule. With the IPRs, the numbers of the three species participated in the INMs are estimated so that the localization characters of the INMs in each band are studied. Further, by the ratio of the IPR of the H atom to that of the O atom, we explore the number of involved OH bond per molecule participated in the INMs. Third, by classifying simulated molecules into subensembles according to the geometry of their local environments or their H-bond configurations, we examine the local-structure effects on the bending and stretching INM bands. All of our results are verified to be insensible to the definition of H-bond. Our conclusions about the intermolecular and intramolecular vibrations in water are given. (C) 2013 AIP Publishing LLC.Item type:Item, Development of a Mucin4-Targeting SPIO Contrast Agent for Effective Detection of Pancreatic Tumor Cells in Vitro and in Vivo(2013-11-28) ;Wu, Shou-Cheng ;Chen, Yu-Jen ;Lin, Yi-Jan ;Wu, Tung-HoWang, Yun-MingIn search of a unique and reliable contrast agent targeting pancreatic adenocarcinoma, new multifunctional nanoparticles (MnMEIO-silane-NH2-(MUC4)-mPEG NPs) were successfully developed in this study. Mucin4-expression levels were determined through different imaging studies in a panel of pancreatic tumor cells (HPAC, BxPC-3, and Panc-1) both in vitro and in vivo studies. The in vitro T-2-weighted MR imaging study in HPAC and Panc-1 tumor cells treated with NPs showed -89.1 +/- 5.7% and -0.9 +/- 0.2% contrast enhancement, whereas in in vivo study, it is found to be -81.5 +/- 4.5% versus -19.6 +/- 5.2% (24 h postinjection, 7.0 T), respectively. The T-2-weighted MR and optical imaging studies revealed that the novel agent can specifically and effectively target to mucin4-expressing tumors in nude mice. Hence, it is suggested that MnMEIO-silane-NH2-(MUC4)-mPEG NPs are able to provide an efficient and targeted delivery of MUC4 antibodies to mucin4-expressing pancreatic tumors.Item type:Item, DEVICE FOR STIMULATING NEURAL REGENERATION AND FABRICATION METHOD THEREOF(2013-11-28) ;Chen Fang-Chung ;Chuang Ming-KaiTan Kim-ShihThe present invention provides a device for stimulating neural regeneration and/or neurite outgrowth and a fabrication method thereof. A photovoltaic component having a substrate, a first conductive layer, an active layer and a second conducting stacked in sequence is formed. The photovoltaic component is encapsulated by an encapsulant with a portion of the first conductive layer and the second conductive layer exposed from the encapsulant. The device is configured to be rolled to form a guiding tube having two open ends and to be placed at a damaged portion of a nerve. When the device is illuminated by light, a photovoltage exists between the first conductive layer and the second conductive layer for producing an electric current, so as to stimulate neural regeneration and repair the damaged portion of a nerve.Item type:Item, Field-Induced Fluorescence Quenching and Enhancement of Porphyrin Sensitizers on TiO2 Films and in PMMA Films(2013-11-28) ;Hsu, Hung-Yu ;Chiang, Hung-Chu ;Hu, Jyun-Yu ;Awasthi, KamleshMai, Chi-LunThree highly efficient porphyrin sensitizers-YD2, YD2-oC8, and YD30, either sensitized on TiO2 films or embedded in PMMA films were investigated using electrophotoluminescence (E-PL) spectra. Under both thin-film conditions, on application of an external electric field we observed the quenching of fluorescence of push-pull porphyrins (YD2 and YD2-oC8) and a slightly enhanced fluorescence of the reference porphyrin without an electron donor group (YD30). A nonfluorescent state with charge separation (CS) is proposed to be involved in both YD2 and YD2-oC8 systems so that the electron injection becomes accelerated in the presence of a strong electric field. In contrast, the retardation of the nonradiative process not involving a CS state was the reason for the field-induced enhancement of fluorescence of YD30. The extent of fluorescence quenching of YD2-oC8 was greater than that of YD2 on TiO2 films, indicating that the ortho-substituted long alkoxyl chains play a key role to accelerate the consecutive electron injection involving the CS state. Our E-PL results indicate that a field-induced variation of fluorescent intensity is related to the efficiency of conversion of solar energy and that further improvement of the performance of devices containing push pull porphyrin dyes is achievable under an applied electric field.Item type:Item, SPIO nanoparticle-stabilized PAA-F127 thermosensitive nanobubbles with MR/US dual-modality imaging and HIFU-triggered drug release for magnetically guided in vivo tumor therapy(2013-11-28) ;Huang, Hsin-Yang ;Hu, Shang-Hsiu ;Hung, Shih-Ya ;Chiang, Chih-ShengLiu, Hao-LiNanobubbles can serve as promising, next-generation theranostic platforms for ultrasound (US) and magnetic resonance (MR) imaging, and combined magnetic targeting (MT) and high-intensity focused ultrasound (HIFU)-triggered drug release for tumor therapy. Nanobubble-based dual contrast enhancement agents encapsulated with perfluoropentane and stabilized with superparamagnetic iron oxide (SPIO) nanoparticles have been synthesized through a single-step emulsion process from thermosensitive F127 and polyacrylic acid (PAA). Both US and MR imaging contrast can be optimized by varying the shell thickness and SPIO-embedded concentration. The US contrast can be enhanced from a mean gray value of 62 to 115, and the MR r(2) value can be enhanced from 164 to 208 (s(-1) mM(-1) Fe) by increasing the SPIO concentration from 14.1 to 28.2 mg/mL, respectively. In vivo investigations of SPIO-embedded nanobubbles in excised tumors under external MT revealed that the US and MR signals change quantitatively compared to the same site without MT. This combined strategy enables the nanobubbles to enhance both passive targeting (increasing the permeability by HIFU) and physical MT of chemotherapeutic drugs to tumors. The integration of functionalities makes this nanobubble system a powerful and viable new tool to achieve simultaneous in vivo tumor imaging and efficacious cancer therapy. (C) 2013 Published by Elsevier B.V.Item type:Item, ELECTROSTATIC DISCHARGE PROTECTION CIRCUIT(2013-11-28) ;Ker Ming-Dou ;Lin Chun-YuWang Chang-TzuAn electrostatic discharge (ESD) protection circuit, suitable for an input stage circuit including a first N channel metal oxide semiconductor (NMOS) transistor, is provided. The ESD protection circuit includes an P channel metal oxide semiconductor (PMOS) transistor and an impedance device, in which the PMOS transistor has a source coupled to a gate of the first NMOS transistor, and a drain coupled to a source of the first NMOS transistor, and the impedance device is coupled between a gate of the PMOS transistor and a first power rail to perform a initial-on ESD protection circuit. The ESD protection circuit formed by the PMOS transistor and the resistor is capable of increasing the turn-on speed of the ESD protection circuit and preventing the input stage circuit from a CDM ESD event.Item type:Item, 台灣樂樂棒球運動發展現況之探討(國立交通大學體育室, 2013-12-01) ;黃崇哲 ;黃杉楹 ;莊國上 ;Chung-Je HuangShan-Ying Huang樂樂棒球(Tee Ball或T-Ball)在台灣已推行十餘年,乃由棒球運動延伸而來,不但較棒球具有安全性及趣味性,也不受場地限制,更有遊戲規則彈性化之特點,近年來被教育部列為重點推廣發展運動項目,在國小校園中獲得廣大迴響,組隊參賽校數、隊伍人數也日趨增加;而該新興運動不論在校園教學,或是課餘假日時間,對學童的閒暇休閒活動也產生莫大影響。本文旨在探討樂樂棒球運動在台灣的發展與現況,透過文獻回顧分析,瞭解樂樂棒球運動在台灣發展的歷程與推動的情形,並進一步探討樂樂棒球運動的特性,及運動發展中可能遇到的阻礙因素;最後再提出建議,期許未來對樂樂棒球運動在台灣的推廣帶來一些助益。Item type:Item, 宛如來自空無的召喚(2013-12-01) ;傑克森 Allyn Jackson ;翁秉仁 ;Shing-Tung Yau Center丘成桐中心數學家格羅騰迪克(Alexandre Grothendieck)對於與數學有關的事物非常敏銳,能夠深刻感受到數學建築結構中精巧與優雅的面向。以他生平的一些高峰為例,他是法國科學高等研究院(IHÉS)的創辦人之一,1966年又獲得費爾茲獎,光這些就足以保證他躋身二十世紀數學的萬神殿。不過這些細節並不足以掌握格羅騰迪克研究的本質,他的成就根源植於更有生機、更質樸的地方。正如他在長篇回憶錄《收割與播種》(Récoltes et Semailles)中所述:「聆聽事物之聲的專注品質,陶冶出研究者創造力與想像力的品質。」(黑體為原作者所加,27頁)。如今格羅騰迪克自己的聲音,體現在他的著作裡,也彷彿得透過空無,才能傳到我們的耳中。高齡八十五歲的他,住在法國南部一處偏遠的小村落裡,已經遯世隱居十餘年。Item type:Item, Distribution and drug susceptibilities of Candida species causing candidemia from a medical center in central Taiwan(2013-12-01) ;Chang, Te-Pin ;Ho, Mao-Wang ;Yang, Yun-Liang ;Lo, Pai-ChangLin, Pei-ShengInvasive fungal infections have increased significantly in the past few decades because of the increase in high-risk populations. To investigate the distribution and drug susceptibilities of such infections, we analyzed all 152 Candida isolates causing candidemia from 2004 to 2006 at the China Medical University Hospital, a medical center in central Taiwan. Candida albicans was the most common species, accounting for 52.6 % of the isolates, followed by C. tropicalis (19.7 %), C. parapsilosis (14.5 %), C. glabrata (8.6 %), C. guilliermondii (3.9 %), and C. pelliculosa (0.7 %). All isolates were susceptible to amphotericin B, anidulafungin, micafungin, and voriconazole according to minimum inhibitory concentrations (MICs) after a 24-h incubation; 0.7 %, 6.6 %, and 7.9 % of isolates were resistant to amphotericin B, fluconazole, and voriconazole, respectively, after 48-h incubation. Both C. albicans and C. parapsilosis had high degrees of agreement for azoles between 24- and 48-h incubation periods, whereas C. glabrata (38.5-46.2 %) and C. tropicalis (56.7-63.3 %) did not. The majority of the isolates with high azole MICs displayed a trailing growth phenotype. Hence, the MICs of different drugs after 24-h incubation may be considered for prognosis of candidemia.Item type:Item, Do journal authors plagiarize? Using plagiarism detection software to uncover matching text across disciplines(2013-12-01) ;Sun, Yu-Chih ;英語教學研究所Institute of Teaching English to speakers of other LanguagesThe current study aims to explore the extent of matching text in published journal articles and how the number of authors and their various official languages influence the extent to which matching text appears. Six hundred journal articles in Science, Technology, Engineering, and Mathematics (STEM) and Social Science were randomly selected and screened by both plagiarism detection software (Turnitin) and human raters(s). The results indicate that disciplinary differences do exist in terms of the degree of matching text incidences. Journal articles in STEM tend to contain significantly more consecutive matching text from other sources than Social Science journal articles. However, it is not clear if this is discipline dependent. In addition, authors tended to have more consecutive text copied from their own previously published works than that of others' publications. Furthermore, the greater the number of authors an article has the more consecutive text-matching can be observed in their published works. Additionally, authors located in contexts wherein English is an official language do not differ significantly from those in contexts wherein English is not an official language on their Turnitin scores and the number of 30-word or longer strings of consecutive matching text from self-published articles and self-and-others' publications combined. (C) 2013 Elsevier Ltd. All rights reserved.Item type:Item, 【第十四屆校友會會務】會長的話(國立陽明大學牙醫校友會, 2013-12)蕭智君Item type:Item, 有五階對稱的晶格嗎?(2013-12-01) ;科里澤克 Michal K ížek ;梭茨 Jakub Šolc ;莎可娃 Alena Šolcová ;黃俊瑋Shing-Tung Yau Center日耳曼學者克卜勒(Johannes Kepler,1571–1630),做為布拉 格神聖羅馬帝國皇帝魯道夫二世的宮廷數學家,尤其以天文學上的發現著名。他從第谷‧布拉赫(Tycho Brahe)觀察火星的數據,所推得的三大行星運動定律,時至現今依舊令人們欽佩。克卜勒另一個傑出的發現是克卜勒方程式,這方程式描述了行星在公轉軌道上時間和位置之間的關係。這個方程式現在通常是從克卜勒第一與第二定律,利用無窮小量微積分推導,但是克卜勒當時則是利用橢圓和圓的幾何性質就得到此結論。Item type:Item, Electrophoretic fabrication and pseudocapacitive properties of graphene/manganese oxide/carbon nanotube nanocomposites(2013-12-01) ;Hung, Chung Jung ;Lin, Pang ;Tseng, Tseung Yuen ;材料科學與工程學系電子工程學系及電子研究所Hybrid nanocomposites provided a synergistic improvement on electrochemical performance and stability for pseudocapacitor. Designed graphene/carbon nanotubes (CNTs)/MnO2 nanocomposites with CNTs electrode (in short, GMC + C) with highly nanoporous framework surface structure are fabricated by a modified electrophoretic deposition (EPD) method. Scanning electron microscopy and transmission electron microscopy analysis demonstrate that the flake-like MnO2 thickness (about less than 10 nm) and uniformly distributed on the porous graphene/CNTs framework. X-ray diffraction shows the formation of birnessite-type MnO2. Pseudocapacitances of the GMC + C electrode calculated by cyclic voltammetry having different scan rates of 5, 20, 50, 100, and 300 mV s(-1) exhibit high specific capacitances of 481, 436, 413, 398, and 372 F g, respectively. Sodium ion diffusion coefficients of the GMC + C electrode show a higher intercalation value of 3.647 x 10(-8) cm(2) s(-1) and deintercalation value of 2.899 x 10(-8) cm(2) s(-1) using chronoamperometry. Moreover, the GMC + C electrode maintains a high specific capacitance of 346 F g(-1), and is about 833% of the initial capacitance after 15,000 charge/discharge cycles. The designed hybrid GMC + C nanocomposites pseudocapacitor electrode using EPD route with the high specific capacitance, fast reaction rate, and high stability, exhibits high potential for practical applications. (C) 2013 Elsevier B.V. All rights reserved.Item type:Item, Efficient Heat Dissipation of Photonic Crystal Microcavity by Mono layer Graphene(2013-12-01) ;Shih, Min-Hsiung ;Li, Lain-Jong ;Yang, Yi-Chun ;Chou, Hsiang-YuLin, Cheng-TeGraphene, which exhibits excellent thermal conductivity, is a potential heat dissipation medium for compact optoelectronic devices. Photonic devices normally produce large-quantity of unwanted heat, and thus, a heat dissipation strategy is urgently needed. In this study, single-layer graphene (SLG) grown by chemical vapor deposition (CVD) is used to cover the surface of a photonic crystal (PhC) cavity, where the heat flux produced by the PhC cavity can be efficiently dissipated along the in-plane direction of the SLG. The thermal properties of the graphene-capped PhC cavity were characterized by experiments and theoretical calculations. The thermal resistance of the SLG-capped PhC cavity obtained from experiments is lower than half of that of a bare PhC cavity. The temperature of a SLG-capped PhC cavity is 45 K lower than that without SLG capping under an optical power of 100 mu W. Our simulation results indicate that SLG receives the majority of the heat fluxes from the device, leading to the efficient heat dissipation. Both the experimental and simulation results suggest that the SLG is a promising material to enhance the heat dissipation efficiency for optoelectronic applications.Item type:Item, 森蘭丸大絕啟動時降低傷害(深河出版有限公司, 2013-12-01)阮郁奇Item type:Item, 全像式集光元件及其製法(2013-12-01) ;謝美莉 ;林尚佑 ;許根玉林烜輝一種全像式集光元件及其製法,信號光經由柱狀透鏡形成柱狀波並入射至一體積全像基材之正面受光面,並同時將參考光由與該全像基材之正面受光面之平行方向入射至該體積全像基材上與該正面受光面之角度不同之側面受光面以進行體積全像記錄,其中,該體積全像基材於該體積全像記錄完成後,可透過該正面受光面接收太陽光以將該太陽光藉由繞射而轉折至位於該側面受光面之法向量的延伸線上之出光面。本發明之全像式集光元件具有較大之集光角度與收光之頻譜範圍,且可大幅提昇集光之效率。Item type:Item, 【第十四屆校友會會務】系主任的話─作伙來打拼(國立陽明大學牙醫校友會, 2013-12)許明倫Item type:Item, 多元普遍主義與左翼倫理政治的內涵-對板垣雄三先生講演的回應(深河出版有限公司, 2013-12-01)張志強Item type:Item, The Vortex Core Excitation Spectrum in Gapped Topological d-wave Superconductors(2013-12-01) ;Rosenstein, Baruch ;Shapiro, Irina ;Shapiro, Boris Y. ;電子物理學系Department of ElectrophysicsThere are indications that some high temperature unconventional superconductors have a "complex" d-wave order parameter (with an admixture of s-wave) leading to nonzero energy gap. Since the coherence length is short and the Fermi energy is relatively small the quasiclassical approach is inapplicable and the more complicated Bogoliubov-deGennes equations should be used to investigate the excitation spectrum of such a material in a magneric field. It turns out that equations for the chiral d-wave superconductor simplify considerably and is the basis for any superconductor of that type with a sufficiently large gap. The spectrum of core excitations of the Abrikosov vortex in an anisotropic 3D sample exhibits several features. Unlike in conventional and gapless superconductors the core has a single excitation mode of order energetic gap for each value of momentum along the field. This has a large impact on thermal transport and vortex dynamics.