Browsing by Issue Date, starting with "2014-06-26"
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Item type:Item, SEMICONDUCTOR DEVICE INTEGRATING PASSIVE ELEMENTS(2014-06-26) ;CHIOU JIN-CHERN ;CHANG CHIH-WEIYANG TZU SENThe present invention provides a semiconductor device integrating passive elements, which applies to analog circuits, wherein capacitors, resistors and inductors are fabricated by a TVS technology. The semiconductor device comprises a substrate; at least one passive element arranged in the substrate; and at least one semiconductor integrated circuit formed in the substrate. The passive element includes a first conductive layer, a first dielectric layer and a second conductive layer, which are stacked sequentially. The first conductive layer and the second conductive layer cooperate with the first dielectric layer to form an equivalent element. The semiconductor circuit is electrically connected with the passive element through the first conductive layer and the second conductive layer to form bidirectional signal transmission paths. The passive elements can be formed on the back side of the substrate to reduce the area occupied by the passive elements in the substrate.Item type:Item, Dual-color decompositions at one-loop level in Yang-Mills theory(2014-06-26) ;Du, Yi-Jian ;Feng, Bo ;Fu, Chih-Hao ;電子物理學系Department of ElectrophysicsIn this work we extend two dual color decompositions of Yang-Mills amplitude to one-loop level. Starting from double-copy expression we translate the Yang-Mills integrand into the dual Del Duca-Dixon-Maltoni formulation and subsequently to the dual color-ordered formula. The dual trace factors are obtained after simultaneously solving the one-loop Kleiss-Kuijf relations, the reflection relation, and the relation that expresses the kinematic factors in the dual Del Duca-Dixon-Maltoni form.Item type:Item, COL11A1 promotes tumor progression and predicts poor clinical outcome in ovarian cancer(2014-06-26) ;Wu, Y-H ;Chang, T-H ;Huang, Y-F ;Huang, H-DChou, C-YBiomarkers that predict disease progression might assist the development of better therapeutic strategies for aggressive cancers, such as ovarian cancer. Here, we investigated the role of collagen type XI alpha 1 (COL11A1) in cell invasiveness and tumor formation and the prognostic impact of COL11A1 expression in ovarian cancer. Microarray analysis suggested that COL11A1 is a disease progression-associated gene that is linked to ovarian cancer recurrence and poor survival. Small interference RNA-mediated specific reduction in COL11A1 protein levels suppressed the invasive ability and oncogenic potential of ovarian cancer cells and decreased tumor formation and lung colonization in mouse xenografts. A combination of experimental approaches, including real-time RT-PCR, casein zymography and chromatin immunoprecipitation (ChIP) assays, showed that COL11A1 knockdown attenuated MMP3 expression and suppressed binding of Ets-1 to its putative MMP3 promoter-binding site, suggesting that the Ets-1-MMP3 axis is upregulated by COL11A1. Transforming growth factor (TGF)-beta (TGF-beta 1) treatment triggers the activation of smad2 signaling cascades, leading to activation of COL11A1 and MMP3. Pharmacological inhibition of MMP3 abrogated the TGF-beta 1-triggered, COL11A1-dependent cell invasiveness. Furthermore, the NF-YA-binding site on the COL11A1 promoter was identified as the major determinant of TGF-beta 1-dependent COL11A1 activation. Analysis of 88 ovarian cancer patients indicated that high COL11A1 mRNA levels are associated with advanced disease stage. The 5-year recurrence-free and overall survival rates were significantly lower (P=0.006 and P=0.018, respectively) among patients with high expression levels of tissue COL11A1 mRNA compared with those with low expression. We conclude that COL11A1 may promote tumor aggressiveness via the TGF-beta 1-MMP3 axis and that COL11A1 expression can predict clinical outcome in ovarian cancer patients.Item type:Item, LICENSE PLATE RECOGNITION SYSTEM AND METHOD(2014-06-26) ;Wu Bing-Fei ;Chen Yen-Lin ;Huang Hao-YuLin Hsin-YuA license plate recognition system and method recognizes a license plate attached to a vehicle and bears a license plate number. The system includes a database module, a reducing module, an image capturing unit, a sorting unit, and a recognizing module. The database module stores license plate position sample type-related data and license plate number sample type-related data whose quantity is reducible by the reducing module. The image capturing unit captures license plate images at different imaging resolutions to generate license plate position image eigenvalue and license plate number image eigenvalue. The sorting unit computes the license plate position image eigenvalue to generate license plate position type-related data and computes the license plate number image eigenvalue to generate license plate number type-related data. The recognizing module compares the license plate number type-related data with the license plate number sample type-related data, thereby recognizing the license plate number.Item type:Item, MUSCULATURE TRAINING DEVICE(2014-06-26) ;Yang Bing-ShiangWen Yu-TangA musculature training device is disclosed. The musculature training device includes an attaching member, a fixing-and-adjusting member coupled to the attaching member, and an elastic member connected to the fixing-and-adjusting member, wherein the fixing-and-adjusting member sets an initial length of the elastic member. When a user move his/her body or limbs to deform the elastic member and change the initial length of the elastic member, the elastic member generates a restoring force that provides a resistance needed for a musculature training around the user's joint. Therefore, the user can train himself anytime and anywhere. Moreover, the user is allowed to perform a single joint musculature training to avoid sport injury and improve training effectiveness.Item type:Item, THREE-DIMENSIONAL INTEGRATED CIRCUIT(2014-06-26) ;Tan An-Nan ;Chen Hung-MingChen Kuan-NengA three-dimensional integrated circuit, including a first adhesive bonding layer, a first chip, a second chip, and an inter-stratum thermal pad, is provided. The first adhesive bonding layer has a first surface and a second surface opposite to each other. The first chip is disposed on the first surface of the first adhesive bonding layer. The first chip includes a hot zone. The second chip is disposed on the second surface of the first adhesive bonding layer. The inter-stratum thermal pad is embedded in the first adhesive bonding layer and faces to the hot zone.Item type:Item, FUEL CELL SYSTEM AND METHOD OF HEAT RECOVERY THEREOF(2014-06-26) ;CHEN Tsung-LinWU Chien-ChangThe present invention provides a fuel cell system, and the fuel cell system comprises a fuel cell, an after burner, a heat exchanger and a reformer. The after burner connects with the fuel cell to receive rest-bar of the fuel cell and produce a gas with high temperature. The heat exchanger comprises a first heat exchanging unit and a second heat exchanging unit connected with the first heat exchanging unit, and the second heat exchanging unit connects with a fuel input pipe for receiving the fuel. The reformer connects with the after burner, the first heat exchanging unit and the second heat exchanging unit separately.Item type:Item, ACTIVE LIQUID CRYSTAL ARRAY DEVICE AND THE FABRICATION MEHTOD THEREOF(2014-06-26) ;JEN Tai-Hsiang ;CHEN Chih-Wei ;CHANG Yu-Cheng ;HSIEH Po-YuanHUANG Yi-PaiAn active liquid crystal array device is provided, A gate control electrode is disposed on the first transparent conductive substrate, a first transparent insulation layer is disposed on the gate control electrode, a liquid crystal control electrode is disposed on the first transparent insulation layer, a second transparent conductive substrate which includes a transparent electrode and a second liquid crystal oriented layer, and a liquid crystal layer is disposed between the first liquid crystal oriented layer and a second liquid crystal oriented layer.Item type:Item, Pros and Cons of the Tuberculosis Drugome Approach - An Empirical Analysis(2014-06-27) ;Chen, Feng-Chi ;Liao, Yu-Chieh ;Huang, Jie-Mao ;Lin, Chieh-HuaChen, Yih-YuanDrug-resistant Mycobacterium tuberculosis (MTB), the causative pathogen of tuberculosis (TB), has become a serious threat to global public health. Yet the development of novel drugs against MTB has been lagging. One potentially powerful approach to drug development is computation-aided repositioning of current drugs. However, the effectiveness of this approach has rarely been examined. Here we select the "TB drugome" approach - a protein structure-based method for drug repositioning for tuberculosis treatment - to (1) experimentally validate the efficacy of the identified drug candidates for inhibiting MTB growth, and (2) computationally examine how consistently drug candidates are prioritized, considering changes in input data. Twenty three drugs in the TB drugome were tested. Of them, only two drugs (tamoxifen and 4-hydroxytamoxifen) effectively suppressed MTB growth at relatively high concentrations. Both drugs significantly enhanced the inhibitory effects of three first-line anti-TB drugs (rifampin, isoniazid, and ethambutol). However, tamoxifen is not a top-listed drug in the TB drugome, and 4-hydroxytamoxifen is not approved for use in humans. Computational re-examination of the TB drugome indicated that the rankings were subject to technical and data-related biases. Thus, although our results support the effectiveness of the TB drugome approach for identifying drugs that can potentially be repositioned for stand-alone applications or for combination treatments for TB, the approach requires further refinements via incorporation of additional biological information. Our findings can also be extended to other structure-based drug repositioning methods.Item type:Item, Pros and Cons of the Tuberculosis Drugome Approach - An Empirical Analysis(2014-06-27) ;Chen, Feng-Chi ;Liao, Yu-Chieh ;Huang, Jie-Mao ;Lin, Chieh-HuaChen, Yih-YuanDrug-resistant Mycobacterium tuberculosis (MTB), the causative pathogen of tuberculosis (TB), has become a serious threat to global public health. Yet the development of novel drugs against MTB has been lagging. One potentially powerful approach to drug development is computation-aided repositioning of current drugs. However, the effectiveness of this approach has rarely been examined. Here we select the "TB drugome" approach - a protein structure-based method for drug repositioning for tuberculosis treatment - to (1) experimentally validate the efficacy of the identified drug candidates for inhibiting MTB growth, and (2) computationally examine how consistently drug candidates are prioritized, considering changes in input data. Twenty three drugs in the TB drugome were tested. Of them, only two drugs (tamoxifen and 4-hydroxytamoxifen) effectively suppressed MTB growth at relatively high concentrations. Both drugs significantly enhanced the inhibitory effects of three first-line anti-TB drugs (rifampin, isoniazid, and ethambutol). However, tamoxifen is not a top-listed drug in the TB drugome, and 4-hydroxytamoxifen is not approved for use in humans. Computational re-examination of the TB drugome indicated that the rankings were subject to technical and data-related biases. Thus, although our results support the effectiveness of the TB drugome approach for identifying drugs that can potentially be repositioned for stand-alone applications or for combination treatments for TB, the approach requires further refinements via incorporation of additional biological information. Our findings can also be extended to other structure-based drug repositioning methods.Item type:Item, 義民祭 下寮總動員(2014-06-28) ;許鴻財 ;Department of Communication and Technology傳播與科技學系在新竹縣新埔鎮枋寮公路上,佇立著一座雄偉的門柱,門柱上面的匾高掛著「褒忠亭」三個大字,兩旁則有金色的石獅守護著,裡面有間紅色屋簷的古老廟宇,廟門前有一個金光閃閃的香爐。Item type:Item, 導讀 主編的話之一(2014-06-28) ;黃湞尹 ;Department of Communication and Technology傳播與科技學系新客家人群像已經邁入第三集:《客家心,台灣情》書中記錄了許多客家人物的生命故事,透過字裡行間的敘述,讀者除了能夠體會每一位作者的用心,也可以了解書中人物,是如何用獨特的客家精神來面對新時代的生活,以及他們對生命的態度。Item type:Item, 日式老豐田,牛犁新生命(2014-06-28) ;鄭宇茹 ;Department of Communication and Technology傳播與科技學系許多人在聽到花蓮縣壽豐鄉的豐田社區,第一個直覺常常是它的名字好特別,而擁有如此日式的名字當然與它的背景有關。在日治時期時這裡是日本人的移民村,第二次世界大戰以後日本雖然戰敗撤退,但建築和建設仍保留了下來,此時原本被限制住在移民村周圍、從西部來的客家二次移民,便接手了這些房子,也配合原本的生活方式改建了這些日式房屋,然後發展屬於他們自己的文化。Item type:Item, 導讀 主編的話之二(2014-06-28) ;Department of Communication and Technology傳播與科技學系《客家心,台灣情》是新客家人群像系列當書的第三本作品,從第一本《承先做後》開始,每一本書的篇數都不斷增加,第三本《客家心,台灣情》共由四十六篇文章組成,作品以傳科系的大一學生為主,更有外系同學的加入。而在文章篇數增加的同時,文章的質感也不斷在提升,除了看得到每一屆新生的成長,也挑 戰每一名編輯的能力與耐力。這一次封面採取較簡單的風格,台灣的圖樣中擺上交通大學客家學院竹北校區新校舍的照片,這也是這本書之所以能出版的幕後推手。而封面上的花朵,其實是從客家花布上取下來的花朵圖案,利用一個大家較為熟悉的客家文化代表,來強調《客家心,台灣情》中的「客家心」精神。封底則是運用客家文化的另一個代表:伯公樹來呈現,除了在左上方記者群的姓名旁放上客家花朵的圖案,呼應封面的客家花布圖案,伯公樹的剪影中放上全書的簡介,希望在整體上能帶來開闊清新的感覺。Item type:Item, 導讀 勤耕「新」田歡喜見「客」(2014-06-28) ;楊睿愷 ;Department of Communication and Technology傳播與科技學系「客家人物」,在傳科101級學弟妹首度嘗試的客家週專題寫作下,揉凝了繽紛新時代與樸質舊傳統的意象。身為傳科系記者一份子的他們,不同於以往媒體報導的觀點,權衡多種聲音、讓在地文化與流行活力接軌,使得「客家」一詞,不再只限於油桐花、圓樓、山歌等商業、生澀且遙遠的意義,而是充滿能動的嶄新力量。Item type:Item, 媽媽散播書香 大溪 愛鎮愛閱讀(2014-06-28) ;許翔 ;Department of Communication and Technology傳播與科技學系走在鼎鼎有名的大溪老街之中,轉幾個彎,就看到一棟老舊的西式建築,乍看之下沒什麼特別,但走近一看,牆上是滿滿的公告,其中一個小黑板上寫著「大溪鎮愛鎮協會」,走進去這棟老房子時,映入眼簾的是一大片舒服的榻榻米,與一整書架的豐富藏書,坐在兩旁的愛心媽媽,立刻熱情地招呼你。Item type:Item, 美濃 找回八音 也唱出新客曲(2014-06-28) ;黃馨儀 ;Department of Communication and Technology傳播與科技學系隨著時代的潮流脈動,你是否還記得以往在山林間勞動時傳來的陣陣歌聲?是否還知曉婚喪喜慶時演奏的樂曲?抑或你聽說過「撮把戲」上演出的笑料?「從前,我曾和他們一起歌唱過、脈搏過和感覺過」,出身於美濃的作家鍾理和曾在書中這樣敘述過他對客家音樂的懷念。而今非昔比,傳統的客家音樂逐漸沒落,欲重新振興卻又少了古早的氣息,在傳統與流行中夾雜,客家音樂該何去何從?Item type:Item, 油桐五月雪 花現美麗金錦(2014-06-28) ;黃詩涵 ;Department of Communication and Technology傳播與科技學系客運行駛在蜿蜒的新竹一一八縣道上,兩旁車窗皆被翠綠的樹葉填滿,這條坡道有個優美的名字:羅馬公路,在晨光的照耀下顯得特別的安靜祥和,沿著羅馬公路行駛,便可到達充滿鄉間悠閒氣息的金錦社區。Item type:Item, 勝興車站 火車不再來 繁華依舊在(2014-06-28) ;洪詩宸 ;Department of Communication and Technology傳播與科技學系彷彿厭倦了前幾日陰雨綿綿的天氣,溫暖的陽光探出頭來,金黃耀眼的光輝照在勝興車站古樸的街道以及來來往往的遊客身上。為數眾多的遊客或在街道中穿梭,或在早已停駛的鐵路上漫步、拍照留念。雖然勝興車站已經是熱門的觀光景點之一,卻仍舊保持著那份純樸的氣息,令人難以想像在轉變為觀光景點前,它曾經歷過一段舊山線停駛的沒落歲月。Item type:Item, 文山阿婆來跳舞 台下熱情唱喝(2014-06-28) ;黃苡齊 ;Department of Communication and Technology傳播與科技學系「練習了好久終於能表演了!」身穿客家民俗舞蹈的服飾,臉上撲滿厚厚的粉還有雙頰上圓圓的腮紅,一群客語中交雜國語的阿婆,興奮地四處向人炫耀「我們文山舞蹈班的舞很厲害喔,等一下就要表演了,有一點點緊張哈哈哈……」。