Browsing by Issue Date, starting with "2014-08-05"

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交大e-News第168期
(2014-08-05)
Secretariat
;
國立交通大學秘書室
Exploring Metabolic Pathways in Vivo by a Combined Approach of Mixed Stable Isotope-Labeled Raman Microspectroscopy and Multivariate Curve Resolution Analysis
(2014-08-05)
Noothalapati, Hemanth
;
Shigeto, Shinsuke
;
應用化學系
;
應用化學系分子科學碩博班
;
Department of Applied Chemistry
Understanding cellular metabolism is a major challenge in current systems biology and has triggered extensive metabolomics research, which in most cases involves destructive analysis. However, the information obtainable only in a nondestructive manner will be required for accurately mapping the global structure of the organism's metabolic network at a given instant. Here we report that metabolic pathways can be explored in vivo by mixed stable isotope-labeled Raman microspectroscopy in conjunction with multivariate curve resolution analysis. As a model system, we studied ergosterol biosynthesis in single living fission yeast cells grown in mixtures of normal and C-13-labeled glucose as the sole carbon source. The multivariate spectral data analysis of space-resolved Raman spectra revealed the intrinsic spectra and relative abundances of all isotopomers of ergosterol whose carbon atoms in the 5,7-diene moiety of the sterol skeleton are either partly or fully substituted with C-13. Our approach is applicable to other metabolites and will earn a place in the toolbox of metabolomic analysis.
Structure of high electron mobility transistor growth on Si substrate and the method thereof
(2014-08-05)
Yi Chang Edward
;
Tang Shih-Hsuan
;
Lin Yueh-Chin
A structure of high electron mobility transistor growth on Si substrate and the method thereof, in particular used for the semiconductor device manufacturing in the semiconductor industry. The UHVCVD system was used in the related invention to grow a Ge film on Si substrate then grow the high electron mobility transistor on the Ge film for the reduction of buffer layer thickness and cost. The function of the Ge film is preventing the formation of silicon oxide when growing III-V MHEMT structure in MOCVD system on Si substrate. The reason of using MHEMT in the invention is that the metamorphic buffer layer in MHEMT structure could block the penetration of dislocation which is formed because of the very large lattice mismatch (4.2%) between Ge and Si substrate.
Exploring Metabolic Pathways in Vivo by a Combined Approach of Mixed Stable Isotope-Labeled Raman Microspectroscopy and Multivariate Curve Resolution Analysis
(2014-08-05)
Noothalapati, Hemanth
;
Shigeto, Shinsuke
;
應用化學系
;
應用化學系分子科學碩博班
;
Department of Applied Chemistry
Understanding cellular metabolism is a major challenge in current systems biology and has triggered extensive metabolomics research, which in most cases involves destructive analysis. However, the information obtainable only in a nondestructive manner will be required for accurately mapping the global structure of the organism\'s metabolic network at a given instant. Here we report that metabolic pathways can be explored in vivo by mixed stable isotope-labeled Raman microspectroscopy in conjunction with multivariate curve resolution analysis. As a model system, we studied ergosterol biosynthesis in single living fission yeast cells grown in mixtures of normal and C-13-labeled glucose as the sole carbon source. The multivariate spectral data analysis of space-resolved Raman spectra revealed the intrinsic spectra and relative abundances of all isotopomers of ergosterol whose carbon atoms in the 5,7-diene moiety of the sterol skeleton are either partly or fully substituted with C-13. Our approach is applicable to other metabolites and will earn a place in the toolbox of metabolomic analysis.
Thermal dissipation substrate
(2014-08-05)
Wu YewChung Sermon
;
Chang Tai-Min
;
Chiu Yu Chia
;
Hu Jen-Li
The present invention related to a method for manufacturing a thermal dissipation substrate and a thermal dissipation substrate. The method includes steps of: (a) providing a substrate body having a surface; (b) forming a plurality of concave regions on the surface; and (c) filling the plurality of concave regions with a plurality of diamond materials. The thermal dissipation substrate includes: a substrate having a surface at a first horizontal; a plurality of regions formed on the surface at a second horizontal; and a plurality of diamond materials having a relatively high thermal coefficient and disposed on the plurality of regions.
Method for selecting transmitting points in a communication system
(2014-08-05)
Huang Chung-Jung
;
Sung Chih-Sheng
;
Lee Ta-Sung
The present invention provides a method for identifying a specific number of communicating points having relatively smallest accumulated path values from a plurality of transmitting points for a receiving point in a communication system. The method includes steps of: (a) defining a first coordination of each of the plurality of transmitting points and the receiving point on a complex plane; (b) transferring the first coordination of the receiving point to a second coordination thereof, in which the second coordination of the receiving point is near an origin of the complex plane; and (c) identifying the specific number of transmitting points having relatively smallest accumulated path values based on the second coordination of the receiving point.
Serum Iron Concentration, but Not Hemoglobin, Correlates with TIMI Risk Score and 6-Month Left Ventricular Performance after Primary Angioplasty for Acute Myocardial Infarction
(2014-08-06)
Huang, Ching-Hui
;
Chang, Chia-Chu
;
Kuo, Chen-Ling
;
Huang, Ching-Shan
;
Chiu, Tzai-Wen
Objective: Anemia is associated with high mortality and poor prognosis after acute coronary syndrome (A(S). Increased red cell distribution width (RDW) is a strong independent predictor for adverse outcomes in ACS. The common underlying mechanism for anemia and increased RDW value is iron deficiency. It is not clear whether serum iron deficiency without anemia affects left ventricular (LV) performance after primary angioplasty for acute myocardial infarction (AMI). We investigated the prognostic value of serum iron concentration on LV ejection fraction (EF) at 6 months and its relationship to thrombolysis in myocardial infarction (TIMI) risk score in post MI patients. Methods: We recruited 55 patients who were scheduled to undergo primary coronary balloon angioplasty after AM I and 54 age- and sex-matched volunteers. Serum iron concentration and interleukin-6 levels were measured before primary angioplasty. LVEF was measured by echocardiography at baseline and after 6 months. TIMI risk score was calculated for risk stratification. Results: Serum iron concentration was significantly lower in those in whom LVEF had not improved >= 10% from baseline (52.7 +/- 24.1 versus 80.8 +/- 50.8 mu g/dl, P = 0.016) regardless of hemoglobin level, and was significantly lower in the AMI group than in the control group (62.5 +/- 37.7 versus 103.0 +/- 38.1 mu g/dl, P<0.001). Trend analysis revealed that serum iron concentration decreased as TIMI risk score increased (P = 0.002). In addition, lower serum iron concentrations were associated with higher levels of inflammatory markers. Multiple linear regression showed that baseline serum iron concentration can predict LV systolic function 6 months after primary angioplasty for AMI even after adjusting for traditional prognostic factors. Conclusion: Hypoferremia is not only a marker of inflammation but also a potential prognostic factor for LV systolic function after revascularization therapy for AMI, and may be a novel biomarker for therapeutic intervention.
Serum Iron Concentration, but Not Hemoglobin, Correlates with TIMI Risk Score and 6-Month Left Ventricular Performance after Primary Angioplasty for Acute Myocardial Infarction
(2014-08-06)
Huang, Ching-Hui
;
Chang, Chia-Chu
;
Kuo, Chen-Ling
;
Huang, Ching-Shan
;
Chiu, Tzai-Wen
Objective: Anemia is associated with high mortality and poor prognosis after acute coronary syndrome (A(S). Increased red cell distribution width (RDW) is a strong independent predictor for adverse outcomes in ACS. The common underlying mechanism for anemia and increased RDW value is iron deficiency. It is not clear whether serum iron deficiency without anemia affects left ventricular (LV) performance after primary angioplasty for acute myocardial infarction (AMI). We investigated the prognostic value of serum iron concentration on LV ejection fraction (EF) at 6 months and its relationship to thrombolysis in myocardial infarction (TIMI) risk score in post MI patients. Methods: We recruited 55 patients who were scheduled to undergo primary coronary balloon angioplasty after AM I and 54 age- and sex-matched volunteers. Serum iron concentration and interleukin-6 levels were measured before primary angioplasty. LVEF was measured by echocardiography at baseline and after 6 months. TIMI risk score was calculated for risk stratification. Results: Serum iron concentration was significantly lower in those in whom LVEF had not improved >= 10% from baseline (52.7 +/- 24.1 versus 80.8 +/- 50.8 mu g/dl, P = 0.016) regardless of hemoglobin level, and was significantly lower in the AMI group than in the control group (62.5 +/- 37.7 versus 103.0 +/- 38.1 mu g/dl, P<0.001). Trend analysis revealed that serum iron concentration decreased as TIMI risk score increased (P = 0.002). In addition, lower serum iron concentrations were associated with higher levels of inflammatory markers. Multiple linear regression showed that baseline serum iron concentration can predict LV systolic function 6 months after primary angioplasty for AMI even after adjusting for traditional prognostic factors. Conclusion: Hypoferremia is not only a marker of inflammation but also a potential prognostic factor for LV systolic function after revascularization therapy for AMI, and may be a novel biomarker for therapeutic intervention.
Electrical Connecting Element and Method for Manufacturing the Same
(2014-08-07)
CHEN Chih
;
LIU Taochi
;
HUANG Yi-Sa
;
LIU Chien-Min
An electrical connecting element for connecting a first substrate and a second substrate and a method for manufacturing the same are disclosed. The method of the present invention comprises: (A) providing a first substrate and a second substrate, wherein a first copper film is formed on the first substrate, a first metal film is formed on the second substrate, a first connecting surface of the first copper film has a (111)-containing surface, and the first metal film has a second connecting surface; and (B) connecting the first copper film and the first metal film to form an interconnect, wherein the first connecting surface of the first copper film is faced to the second connecting surface of the first metal film.
A facile green antisolvent approach to Cu2+-doped ZnO nanocrystals with visible-light-responsive photoactivities
(2014-08-07)
Lu, Yi-Hsuan
;
Lin, Wei-Hao
;
Yang, Chao-Yao
;
Chiu, Yi-Hsuan
;
Pu, Ying-Chih
An environmentally benign antisolvent method has been developed to prepare Cu2+-doped ZnO nanocrystals with controllable dopant concentrations. A room temperature ionic liquid, known as a deep eutectic solvent (DES), was used as the solvent to dissolve ZnO powders. Upon the introduction of the ZnO-containing DES into a bad solvent which shows no solvation to ZnO, ZnO was precipitated and grown due to the dramatic decrease of solubility. By adding Cu2+ ions to the bad solvent, the growth of ZnO from the antisolvent process was accompanied by Cu2+ introduction, resulting in the formation of Cu2+-doped ZnO nanocrystals. The as-prepared Cu2+-doped ZnO showed an additional absorption band in the visible range (400-800 nm), which conduced to an improvement in the overall photon harvesting efficiency. Time-resolved photoluminescence spectra, together with the photovoltage information, suggested that the doped Cu2+ may otherwise trap photoexcited electrons during the charge transfer process, inevitably depressing the photoconversion efficiency. The photoactivity of Cu2+-doped ZnO nanocrystals for photoelectrochemical water oxidation was effectively enhanced in the visible region, which achieved the highest at 2.0 at% of Cu2+. A further increase in the Cu2+ concentration however led to a decrease in the photocatalytic performance, which was ascribed to the significant carrier trapping caused by the increased states given by excessive Cu2+. The photocurrent action spectra illustrated that the enhanced photoactivity of the Cu2+-doped ZnO nanocrystals was mainly due to the improved visible photon harvesting achieved by Cu2+ doping. These results may facilitate the use of transition metal ion-doped ZnO in other photoconversion applications, such as ZnO based dye-sensitized solar cells and magnetism-assisted photocatalytic systems.
A facile green antisolvent approach to Cu2+-doped ZnO nanocrystals with visible-light-responsive photoactivities
(2014-08-07)
Lu, Yi-Hsuan
;
Lin, Wei-Hao
;
Yang, Chao-Yao
;
Chiu, Yi-Hsuan
;
Pu, Ying-Chih
An environmentally benign antisolvent method has been developed to prepare Cu2+-doped ZnO nanocrystals with controllable dopant concentrations. A room temperature ionic liquid, known as a deep eutectic solvent (DES), was used as the solvent to dissolve ZnO powders. Upon the introduction of the ZnO-containing DES into a bad solvent which shows no solvation to ZnO, ZnO was precipitated and grown due to the dramatic decrease of solubility. By adding Cu2+ ions to the bad solvent, the growth of ZnO from the antisolvent process was accompanied by Cu2+ introduction, resulting in the formation of Cu2+-doped ZnO nanocrystals. The as-prepared Cu2+-doped ZnO showed an additional absorption band in the visible range (400-800 nm), which conduced to an improvement in the overall photon harvesting efficiency. Time-resolved photoluminescence spectra, together with the photovoltage information, suggested that the doped Cu2+ may otherwise trap photoexcited electrons during the charge transfer process, inevitably depressing the photoconversion efficiency. The photoactivity of Cu2+-doped ZnO nanocrystals for photoelectrochemical water oxidation was effectively enhanced in the visible region, which achieved the highest at 2.0 at% of Cu2+. A further increase in the Cu2+ concentration however led to a decrease in the photocatalytic performance, which was ascribed to the significant carrier trapping caused by the increased states given by excessive Cu2+. The photocurrent action spectra illustrated that the enhanced photoactivity of the Cu2+-doped ZnO nanocrystals was mainly due to the improved visible photon harvesting achieved by Cu2+ doping. These results may facilitate the use of transition metal ion-doped ZnO in other photoconversion applications, such as ZnO based dye-sensitized solar cells and magnetism-assisted photocatalytic systems.
Plasmonic nanostructures for light trapping in organic photovoltaic devices
(2014-08-07)
Chou, Chun-Hsien
;
Chen, Fang-Chung
;
光電工程學系
;
顯示科技研究所
;
Department of Photonics
Over the past decade, we have witnessed rapid advances in the development of organic photovoltaic devices (OPVs). At present, the highest level of efficiency has surpassed 10%, suggesting that OPVs have great potential to become competitive with other thin-film solar technologies. Because plasmonic nanostructures are likely to further improve the efficiency of OPVs, this Article reviews recent progress in the development of metal nanostructures for triggering plasmonic effects in OPVs. First, we briefly describe the physical fundamentals of surface plasmons (SPs). Then, we discuss recent approaches toward increasing the light trapping efficiency of OPVs through the incorporation of plasmonic structures. Finally, we provide a brief outlook into the future use of SPs in highly efficient OPVs.
STREAMING ENCODER, PROSODY INFORMATION ENCODING DEVICE, PROSODY-ANALYZING DEVICE, AND DEVICE AND METHOD FOR SPEECH SYNTHESIZING
(2014-08-07)
Chen Sin-Horng
;
Wang Yih-Ru
;
Chiang Chen-Yu
;
Hsieh Chiao-Hua
A speech-synthesizing device includes a hierarchical prosodic module, a prosody-analyzing device, and a prosody-synthesizing unit. The hierarchical prosodic module generates at least a first hierarchical prosodic model. The prosody-analyzing device receives a low-level linguistic feature, a high-level linguistic feature and a first prosodic feature, and generates at least a prosodic tag based on the low-level linguistic feature, the high-level linguistic feature, the first prosodic feature and the first hierarchical prosodic model. The prosody-synthesizing unit synthesizes a second prosodic feature based on the hierarchical prosodic module, the low-level linguistic feature and the prosodic tag.
GRAPHITE OXIDE AND/OR GRAPHENE PREPARATION METHOD
(2014-08-07)
WEI KUNG-HWA
;
DANG VAN THANH
A graphite oxide or graphene preparation method includes providing a plasma electrolytic apparatus, where an electrolytic solution is provided and a graphite electrode is configured as a cathode of the plasma electrolytic apparatus; and providing a cathodic current so as to initiate a plasma electrolytic process at the graphite cathode to obtain graphite oxide or graphene. The graphite oxide can be synthesized through plasma electrolytic processing at relatively low temperature under atmospheric pressure within a very short period of time, without the need for concentrated acids or strong oxidizing agents. The present invention may prepare graphite oxide with plasma electrolytic process directly from graphite, without requiring any prior purification. This plasma electrolytic process of the present invention is quite promising and provided with advantages such as low cost, simple setup, high efficiency, and environmental friendliness.
Dirac fermion relaxation and energy loss rate near the Fermi surface in monolayer and multilayer graphene
(2014-08-07)
Luo, C. W.
;
Tseng, P. S.
;
Chen, H. -J.
;
Wu, K. H.
;
Li, L. J.
Ultrafast dynamics of Dirac fermions near the Fermi surface in monolayer and multilayer graphene are revealed using optical pump mid-infrared probe spectroscopy. The energy loss rate of Dirac fermions is also determined via energy-resolved transient transmissivity spectra, which is significantly suppressed as the number of layers in graphene increases.
Isatin derivatives and isoxazolinones from tandem anti-Michael three-component assembly and oxidation
(2014-08-10)
Deng, Jie-Cheng
;
Chuang, Shih-Ching
;
交大名義發表
;
National Chiao Tung University
Energy dependent oscillations in the angular distribution of O(D-1) + Xe inelastic scattering
(2014-08-10)
Garofalo, Lauren A.
;
Smith, Mica C.
;
Boering, Kristie A.
;
Lin, Jim Jr-Min
;
應用化學系
Theoretical study on absorption, fluorescence, and resonance Raman scattering spectra of silver cluster, Ag-n and Ag-n-pyridine complexes (n=1-3)
(2014-08-10)
Chen, Si Ying
;
Lin, Sheng Hisen
;
Chang, A. Hsiu-Hua
;
應用化學系
;
Department of Applied Chemistry
Uncover nucleophilic conjugate 1,3-addition of phosphines to polyynoates
(2014-08-10)
Chuang, Shih-Ching
;
Deng, Jie-Cheng
;
Kuo, Chih-Wei
;
應用化學系
;
Department of Applied Chemistry
Preparation of imprinted organic-inorganic hybrids for exhibiting high adsorption and recognition capability
(2014-08-10)
Tseng, Kai-hsun
;
Chang, Sue-min
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環境工程研究所
;
Institute of Environmental Engineering