Browsing by Issue Date, starting with "2014-09-04"

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Knowledge-based identification of sleep stages based on two forehead electroencephalogram channels
(2014-09-04)
Huang, Chih-Sheng
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Lin, Chun-Ling
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Ko, Li-Wei
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Liu, Shen-Yi
;
Su, Tung-Ping
Sleep quality is important, especially given the considerable number of sleep-related pathologies. The distribution of sleep stages is a highly effective and objective way of quantifying sleep quality. As a standard multi-channel recording used in the study of sleep, polysomnography (PSG) is a widely used diagnostic scheme in sleep medicine. However, the standard process of sleep clinical test, including PSG recording and manual scoring, is complex, uncomfortable, and time-consuming. This process is difficult to implement when taking the whole PSG measurements at home for general healthcare purposes. This work presents a novel sleep stage classification system, based on features from the two forehead EEG channels FP1 and FP2. By recording EEG from forehead, where there is no hair, the proposed system can monitor physiological changes during sleep in a more practical way than previous systems. Through a headband or self-adhesive technology, the necessary sensors can be applied easily by users at home. Analysis results demonstrate that classification performance of the proposed system overcomes the individual differences between different participants in terms of automatically classifying sleep stages. Additionally, the proposed sleep stage classification system can identify kernel sleep features extracted from forehead EEG, which are closely related with sleep clinician\'s expert knowledge. Moreover, forehead EEG features are classified into five sleep stages by using the relevance vector machine. In a leave-one-subject-out cross validation analysis, we found our system to correctly classify five sleep stages at an average accuracy of 76.7 +/- 4.0 (SD) % [average kappa 0.68 +/- 0.06 (SD)]. Importantly, the proposed sleep stage classification system using forehead EEG features is a viable alternative for measuring EEG signals at home easily and conveniently to evaluate sleep quality reliably, ultimately improving public healthcare.
The depletion of securin enhances butein-induced apoptosis and tumor inhibition in human colorectal cancer
(2014-09-05)
Huang, Yu-Tin
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Lin, Chien-I
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Chien, Pei-Hsuan
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Tang, Tsai-Tai
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Lin, Johnson
Butein (3,4,2\',4\'-tetrahydroxychalcone) is a promising natural polyphenolic compound that shows the growth inhibitory activity in human cancer cells; however, the precise mechanism is still unclear. Securin plays pivotal role in cancer cell proliferation and tumorigenesis. Here, we report the presence of securin that could modulate apoptosis and tumor growth ability in the butein-treated human colorectal cancer. Butein induced caspase-3 activation and PARP protein cleavage for apoptosis induction in human colorectal cancer cells. Interestingly, butein reduced the securin protein levels but conversely increased the phospho-histone H3 proteins, mitotic arrest and abnormal chromosomes segregation in cancer cells. The securin-null colorectal cancer cells were more sensitive on the reduction of cell viability than the securin-wild type cancer cells following butein treatment. The loss of securin in human colorectal cancer cells decreased tumor growth ability in nude mice. Moreover, butein reduced the tumor size of xenografted human colorectal tumors of nude mice. Taken together, this study demonstrates for the first time that the depletion of securin mediates the butein-induced apoptosis and colorectal tumor inhibition. (C) 2014 Elsevier Ireland Ltd. All rights reserved.
交大e-News第170期
(2014-09-05)
Secretariat
;
國立交通大學秘書室
Evaluation of thermal performance of all-GaN power module in parallel operation
(2014-09-05)
Chou, Po-Chien
;
Cheng, Stone
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Chen, Szu-Hao
;
交大名義發表
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機械工程學系
This work presents an extensive thermal characterization of a single discrete GaN high-electron-mobility transistor (HEMT) device when operated in parallel at temperatures of 25 degrees C-175 degrees C. The maximum drain current (I-D (max)), on-resistance (R-ON), pinch-off voltage (V-p) and peak transconductance (g(m)) at various chamber temperatures are measured and correlations among these parameters studied. Understanding the dependence of key transistor parameters on temperature is crucial to inhibiting the generation of hot spots and the equalization of currents in the parallel operation of HEMTs. A detailed analysis of the current imbalance between two parallel HEMT cells and its consequential effect on the junction temperature are also presented. The results from variations in the characteristics of the parallel-connected devices further verify that the thermal stability and switching behavior of these cells are balanced. Two parallel HEMT cells are operated at a safe working distance from thermal runaway to prevent destruction of the hottest cell. (C) 2014 Elsevier Ltd. All rights reserved.
Efficient inverted quasi-bilayer organic solar cells fabricated by using non-halogenated solvent processes
(2014-09-07)
Chang, Jung-Hao
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Wang, Hsiao-Fang
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Lin, Wei-Chieh
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Chiang, Kai-Ming
;
Chen, Kuan-Chen
Here we demonstrate the fabrication of novel, "quasi-bilayer" inverted organic photovoltaic devices using halogen-free solvents. The inferior solubility of pristine fullerene in non-halogenated solvents was used to control the interpenetration of upper polymeric donor layers with bottom fullerene layers. Notably, island-like nano-morphologies were revealed by AFM, SEM, TEM, cross-sectional TEM images and PL quenching measurement. Correlation between device performance, thin-film nano-morphology and ac impedance was observed. High efficiencies of 6.55% and 7.15% were observed for PBDTTT-C-T and PTB7 cells, respectively. These results demonstrate that this novel process not only offers an effective new method to control the morphology of solar active layers but, more importantly, could also be applied to a wide range of current material systems to produce efficient devices that comply with the non-toxic halogen-free requirement.
Efficient inverted quasi-bilayer organic solar cells fabricated by using non-halogenated solvent processes
(2014-09-07)
Chang, Jung-Hao
;
Wang, Hsiao-Fang
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Lin, Wei-Chieh
;
Chiang, Kai-Ming
;
Chen, Kuan-Chen
Here we demonstrate the fabrication of novel, "quasi-bilayer" inverted organic photovoltaic devices using halogen-free solvents. The inferior solubility of pristine fullerene in non-halogenated solvents was used to control the interpenetration of upper polymeric donor layers with bottom fullerene layers. Notably, island-like nano-morphologies were revealed by AFM, SEM, TEM, cross-sectional TEM images and PL quenching measurement. Correlation between device performance, thin-film nano-morphology and ac impedance was observed. High efficiencies of 6.55% and 7.15% were observed for PBDTTT-C-T and PTB7 cells, respectively. These results demonstrate that this novel process not only offers an effective new method to control the morphology of solar active layers but, more importantly, could also be applied to a wide range of current material systems to produce efficient devices that comply with the non-toxic halogen-free requirement.
Critical interpretation of CH- and OH- stretching regions for infrared spectra of methanol clusters (CH3OH)(n) (n=2-5) using self-consistent-charge density functional tight-binding molecular dynamics simulations
(2014-09-07)
Nishimura, Yoshifumi
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Lee, Yuan-Pern
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Irle, Stephan
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Witek, Henryk A.
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交大名義發表
Vibrational infrared (IR) spectra of gas-phase O-H center dot center dot center dot O methanol clusters up to pentamer are simulated using self-consistent-charge density functional tight-binding method using two distinct methodologies: standard normal mode analysis and Fourier transform of the dipole time-correlation function. The twofold simulations aim at the direct critical assignment of the C-H stretching region of the recently recorded experimental spectra [H.-L. Han, C. Camacho, H. A. Witek, and Y.-P. Lee, J. Chem. Phys. 134, 144309 (2011)]. Both approaches confirm the previous assignment (ibid.) of the C-H stretching bands based on the B3LYP/ANO1 harmonic frequencies, showing that nu(3), nu(9), and nu(2) C-H stretching modes of the proton-accepting (PA) and proton-donating (PD) methanol monomers experience only small splittings upon the cluster formation. This finding is in sharp discord with the assignment based on anharmonic B3LYP/VPT2/ANO1 vibrational frequencies (ibid.), suggesting that some procedural faults, likely related to the breakdown of the perturbational vibrational treatment, led the anharmonic calculations astray. The IR spectra based on the Fourier transform of the dipole time-correlation function include new, previously unaccounted for physical factors such as non-zero temperature of the system and large amplitude motions of the clusters. The elevation of temperature results in a considerable non-homogeneous broadening of the observed IR signals, while the presence of large-amplitude motions (methyl group rotations and PA-PD flipping), somewhat surprisingly, does not introduce any new features in the spectrum. (C) 2014 AIP Publishing LLC.
One-Pot Synthesis of Highly Substituted Polyheteroaromatic Compounds by Rhodium(III)-Catalyzed Multiple C-H Activation and Annulation
(2014-09-08)
Jayakumar, Jayachandran
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Parthasarathy, Kanniyappan
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Chen, Yi-Hsiang
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Lee, Tai-Hua
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Chuang, Shih-Ching
A new method for the synthesis of highly substituted naphthyridine-based polyheteroaromatic compounds in high yields proceeds through rhodium(III)-catalyzed multiple CH bond cleavage and CC and CN bond formation in a one-pot process. Such highly substituted polyheteroaromatic compounds have attracted much attention because of their unique -conjugation, which make them suitable materials for organic semiconductors and luminescent materials. Furthermore, a possible mechanism, which involves multiple chelation-assisted ortho CH activation, alkyne insertion, and reductive elimination, is proposed for this transformation.
Light emitting device with graded composition hole tunneling layer
(2014-09-09)
Wang Chao-Hsun
;
Kuo Hao-Chung
A light emitting device with graded composition hole tunneling layer is provided. The device comprises a substrate and an n-type semiconductor layer is disposed on the substrate, in which the n-type semiconductor layer comprises a first portion and a second portion. A graded composition hole tunneling layer is disposed on the first portion of the n-type semiconductor layer. An electron blocking layer is disposed on the graded composition hole tunneling layer. A p-type semiconductor layer is disposed on the electron blocking layer. A first electrode is disposed on the p-type semiconductor layer, and a second electrode is disposed on the second portion of the n-type semiconductor layer and is electrical insulated from the first portion of the n-type semiconductor. The graded composition hole tunneling layer is used as the quantum-well to improve the transport efficiency of the holes to increase the light emitting efficiency of the light emitting device.
Bianchi type I expanding universe in Weyl-invariant massive gravity
(2014-09-10)
Kao, W. F.
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Lin, Ing-Chen
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物理研究所
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Institute of Physics
We will study the cosmological evolutions of aWeyl-invariant de Rham, Gabadadze, and Tolley (dRGT) massive gravity theory with a general fiducial metric. In the unitary gauge, this model is equivalent to a massive gauge field coupled to the dRGT massive gravity model. The massive gravity terms will serve as an effective cosmological constant for all metric spaces if the fiducial metric is treated as an auxiliary field. A further discussion will also be addressed on the bimetric theory. In particular, we will discuss the role played by the Weyl vector boson in Bianchi type I expanding space.
根據路況調整充電狀態之充電裝置及其方法
(2014-09-11)
陳烈武
;
曾煜棋
;
吳建澄
本發明係揭露一種根據路況調整充電狀態之充電裝置及其方法，應用於一載具，其包含：一定位模組、一處理模組、一發電模組以及一驅動模組。定位模組係提供一地理資訊。處理模組根據地理資訊計算與判斷一路段斜率，並產生一驅動訊號。發電模組連結一待充電裝置，且發電模組利用載具之車輪帶動一滾輪，進而驅動發電模組發電，並對待充電裝置充電。驅動模組設置於載具上，並以一活動臂連結發電模組。驅動模組接收驅動訊號，並根據驅動訊號來驅動活動臂，以控制發電模組移入或移出車輪。
乙醇重組器觸媒組成物及乙醇重組器觸媒之製備方法
(2014-09-11)
李積琛
;
翁聖豐
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陳昀聲
;
王允欣
一種乙醇重組器觸媒之製備方法，包括以下步驟：首先，將第一金屬前驅物、第二金屬前驅物及第三金屬前驅物在室溫下混合於一有機媒介中，以形成一混合物；接著，將一介面活性劑添加入該混合物中，並於30℃至50℃下靜置3至7天，以形成一凝膠態溶液；之後，以350℃至550℃之第一段溫度進行鍛燒1至5小時，並以800℃至1000℃之第二段溫度進行鍛燒1至5小時，即製成一乙醇重組器觸媒。本發明另提供一種乙醇重組器觸媒組成物。
Core Excitation, Specific Dissociation, and the Effect of the Size of Aromatic Molecules Connected to Oxygen: Phenyl Ether and 1,3-Diphenoxybenzene
(2014-09-11)
Lin, Yi-Shiue
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Lin, Shu-Yu
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Lee, Yuan T.
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Tseng, Chien-Ming
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Ni, Chi-Kung
Near-edge X-ray absorption fine structure (NEXAFS) spectra of phenyl ether at the carbon K-edge and 1,3-diphenoxybenzene at both the carbon and oxygen K-edges were measured in the total ion yield mode using X-rays from a synchrotron and a reflectron time-of-flight mass spectrometer. Time-dependent density functional theory was adopted to calculate the carbon and oxygen K-edge NEXAFS spectra of phenol, phenyl ether, and 1,3-diphenoxybenzene. The assignments and a comparison of the experimental and calculated spectra are presented. The mass spectra of ionic products formed after X-ray absorption at various excitation energies are also reported. Specific dissociations were observed for the 1s --> pi* transition of phenyl ether. In comparison with phenol and phenyl ether, the dependence of the fragmentation on the excitation site and destination state was weak in 1,3-diphenoxybenzene, likely as a result of delocalization of the valence electrons and rapid randomization of energy.
時域反射式液面與刷深量測裝置及其方法
(2014-09-11)
林志平
;
鐘志忠
本發明係關於一種時域反射式液面與刷深量測裝置及其方法，特別是一種利用時域反射裝置與方法者，藉以同時監測液面與沖刷深度變化。本發明首先在時域反射導波器設計方面，採用結合類似地錨鋼索的導波器設計，提出符合安裝實務的設計，並考慮導體絕緣處理，解決訊號衰減問題；在量測液面與沖刷深度的量測方法，基於不同介質之電磁波速不同，本發明結合反射訊號辨識與波傳速度標定與分析流程，提出較可靠的訊號分析方法。
車道定位系統、車道定位方法及路面標記
(2014-09-11)
曾煜棋
;
陳烈武
;
鄭任翔
本發明揭露一種車道定位系統與方法，用於判斷車道之位置，其中該車道定位系統包含影像擷取單元、影像識別單元以及處理單元。影像擷取單元擷取車道之車道影像，所述車道影像至少顯示車道兩旁之第一車道線與第二車道線其中之一。影像識別單元由車道影像至少識別出第一車道線上的第一路面標記與第二車道線上的第二路面標記其中之一後，依據第一路面標記或第二路面標記以產生車道位置信號。處理單元依據車道位置信號判斷車道之位置。藉此，本發明可利用路面標記達到車道辨識的功效。
ENGINEERING CHANGE ORDER HOLD TIME FIXING METHOD
(2014-09-11)
JIANG Hiu-Ru
;
YANG Yu-Ming
;
HO Sung-Ting
An ECO hold time fixing method fulfills a short path padding in a placed and routed design by a minimum capacitance insertion. In the method, a padding value determination step receives the placed and routed design and is based on a cell library, timing constraints, and a timing analysis report to determine padding values and locations required for each gate of the placed and routed design to output. A load/buffer allocation step is based on a spare cell information, a dummy metal information, and the padding values and locations to achieve the short path padding in the placed and routed design.
可電壓控制之光學元件及其製備方法
(2014-09-11)
劉立偉
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陳致維
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蘇雍仁
;
黃乙白
一種可電壓控制之光學元件，其包括：第一基板；第一導體層，設置在第一基板上；液晶層，設置在第一導體層之上；半導體層，設置在液晶層之上；第二導體層，設置在半導體層上；及第二基板，設置在第二導體層上。
NANOPARTICLE DRUG CARRIER, PHARMACEUTICAL COMPOSITION AND MANUFACTURING METHOD THEREOF
(2014-09-11)
Chen San-Yuan
;
Li Wei-Ming
A pharmaceutical composition is provided. The pharmaceutical composition includes a nanoparticle, a shell and a drug, wherein the nanoparticle has an outer surface and the drug is mixed with the shell and is formed on the outer surface.
基於擴增實境與雲端計算之應用程式執行方法與系統
(2014-09-11)
陳烈武
;
曾煜棋
;
彭昱豪
一種創新的應用程式執行方法與系統，可利用動態影像或靜態照片來讓使用者取得欲通訊/查詢對象之識別帳號並觸發特定程式/網頁功能的人性化介面。本發明讓使用者不必自行輸入欲通訊對象的識別帳號，如E-Mail位址、MSN識別、Facebook識別、FTP IP、甚至是關鍵字等，只需一指拖曳人臉到應用程式圖示/網頁圖示上或將該應用程式圖示/網頁圖示拖曳到該人臉上，即可輕鬆完成執行應用程式/網站功能的過程，有效地降低使用者操作複雜度，並提供簡易的應用軟體與網站服務操作方法。
INTEGRATED PASSIVE OPTICAL NETWORK (PON) SYSTEM
(2014-09-11)
CHOW CHI-WAI
;
YEH CHIEN-HUNG
;
SUNG JIUN-YU
An integrated passive optical network system is disclosed. The system comprises an optical distribution network (ODN), a time-division multiplexing (TDM)-optical line terminal (OLT), a wavelength-division multiplexing (WDM)-optical line terminal (OLT), a plurality of time-division multiplexing (TDM)-optical network units (ONUs), and at least one wavelength-division multiplexing (WDM)-optical network unit (ONU) comprising a first filter. The TDM-OLT and the WDM-OLT respectively transmit a first optical signal carrying a first downstream signal and a second optical signal carrying a second downstream signal to the ONUs through the ODN, and wavelengths of the second optical signal and the first optical signal are different. The TDM-ONUs respectively retrieve the first downstream signal The WDM-ONU uses the first filter to retrieve the second downstream signal.