Browsing by Issue Date, starting with "2015-07-07"

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The First Residue of the PWWP Motif Modulates HATH Domain Binding, Stability, and Protein-Protein Interaction
(2015-07-07)
Hung, Yi-Lin
;
Lee, Hsia-Ju
;
Jiang, Ingjye
;
Lin, Shang-Chi
;
Lo, Wei-Cheng
Hepatoma-derived growth factor (hHDGF) and HDGF-related proteins (HRPs) contain conserved N-terminal HATH domains with a characteristic structural motif; namely the PWWP motif. The HATH domain has attracted attention because of its ability to bind with heparin/heparan sulfate, DNA, and methylated histone peptide. Depending on the sequence of the PWWP motif, HRP HATHs are classified into P-type (Pro-His-Trp-Pro) and A-type (Ala-His-Trp-Pro) forms. A-type HATH is highly unstable and tends to precipitate in solution. We replaced the Pro residue in P-type HATH(HDGF) with Ala and evaluated the influence on structure, dynamics, and ligand binding. Nuclear magnetic resonance (NMR) hydrogen/deuterium exchange and circular dichroism (CD) measurements revealed reduced stability. Analysis of NMR backbone N-15 relaxations (R-1, R-2, and nuclear Overhauser effect) revealed additional backbone dynamics in the interface between the beta-barrel and the C-terminal helix bundle. The beta 1-beta 2 loop, where the AHWP sequence is located, has great structural flexibility, which aids HATH-HATH interaction through the loop. A-type HATH, therefore, shows a stronger tendency to aggregate when binding with heparin and DNA oligomers. This study defines the role of the first residue of the PWWP motif in modulating HATH domain stability and oligomer formation in binding.
Importance of Internal Porosity for Glucan Adsorption in Mesoporous Carbon Materials
(2015-07-07)
Chung, Po-Wen
;
Charmot, Alexandre
;
Click, Timothy
;
Lin, Yuchun
;
Bae, YounJue
To better understand the adsorption of long-chain poly(1 -> 4)beta-D-glucans on carbon surfaces as well as interactions responsible for this adsorption, we use a comparative study involving mesoporous carbon silica composite materials that have been etched to varying degrees and all-atom molecular dynamics simulations. The materials synthesized as part of this etching study consist of an as-synthesized composite material (MCN-MSN), MCN-MSN-0.5 (composite materials consisting of 50% carbon by mass), MCN-MSN-0.3 (composite materials consisting of 70% carbon by mass), and MCN, in which silica etching was conducted using an aqueous ethanolic solution of either NaOH or HF. Data for the adsorption of long-chain glucans to these materials from concentrated aqueous HCl (37 wt %) solution demonstrate a direct relationship between the amount of beta-glu adsorption and the magnitude of exposed carbon mesopore surface area, which systematically increases and is also accompanied by an increase in the mesopore size during silica etching. This demonstrates beta-glu adsorption as occurring on internal carbon mesopores rather than exclusively on the external carbon surface. These experimental data on adsorption were corroborated by molecular dynamics (MD) simulations of beta-glu adsorption to a graphene bilayer separated by a distance of 3.2 nm, chosen to correspond to the carbon mesopore diameter of the experimental system. Simulation results using a variety of beta-glu solvent systems demonstrate the rapid adsorption of a beta-glu strand on the graphitic carbon surface via axial coupling and are consistent with experimentally observed trends in fast adsorption kinetics. Solvent-mediated effects such as small-scale hydrophobicity and preferential interactions with ions are shown to play important roles in modulating glucan adsorption to carbon surfaces, whereas experimental data on hydrophobically modified silica demonstrate that hydrophobicity in and of itself is insufficient to cause beta-glu adsorption from concentrated aqueous HCl solution.
Ovarian Suspension With Adjustable Sutures: An Easy and Helpful Technique for Facilitating Laparoendoscopic Single-Site Gynecologic Surgery
(2015-07-08)
Chen, Kuo-Hu
;
Chen, Li-Ru
;
Seow, Kok-Min
;
機械工程學系
;
Department of Mechanical Engineering
Study Objective: To describe a method of ovarian suspension with adjustable sutures (OSAS) for facilitating laparoendoscopic single-site gynecologic surgery (LESS) and to investigate the effect of OSAS on LESS. Design: Prospective cohort study (Canadian Task Force classification: II-2). Setting: University teaching hospital. Patients: One hundred seventy-eight patients with benign 5-to 15-cm cystic ovarian tumors who underwent LESS with OSAS (suspension group, n = 90) and without OSAS (control group, n = 88). Interventions: For patients who underwent OSAS (suspension group), 1 end of double-head straight needles with a polypropylene suture was inserted into the pelvic cavity through the abdominal skin to penetrate the cyst or ovarian parenchyma and puncture outside the abdominal skin. After cutting off the needles, both sides of the remaining suture were held together by a clamp, without knotting, so that the manipulator could "lift," "loosen," or "fix" the stitches to adjust the tension. Measurements and Main Results: The average time to create OSAS was 2.9 min. For the suspension and control groups, the average blood loss was 81.4 and 131.8 mL (p < .001), and the operative time was 42.0 and 61.3 min (p < .001), respectively. There were no significant differences in the incidence of complications (5.6% vs 9.1%; p = .365), but there were significant differences in conversions to standard non single-site laparoscopy (5.6% vs 15.9%; p = .025) and laparotomy (1.1% vs 6.8%; p = .040). Logistic regression analysis revealed that the ratios of conversion to standard non single-site laparoscopy (odds ratio [On 0.126; 95% confidence interval [C1], 0.311-0.508) and laparotomy (OR, 0.032; 95% CI, 0.002-0.479) were much lower in the suspension group; the risk of complications was comparable (OR, 0.346; 95% CI, 0.085-1.403). Conclusion: OSAS is an easy, safe, and feasible method that offers advantages during LESS. Although routine use of OSAS is not necessary, OSAS can be considered during LESS to facilitate the surgery. (C) 2015 AAGL. All rights reserved.
GATE-BOOSTING RECTIFIER AND METHOD OF PERMITTING CURRENT TO FLOW IN FAVOR OF ONE DIRECTION WHEN DRIVEN BY AC INPUT VOLTAGE
(2015-07-09)
Wang Yu-Jiu
;
Liao I-No
;
Tsai Chao-Han
;
Pakasiri Chatrpol
A current-rectifying device includes a switching component and an impedance transformer. A conductance between first and second nodes of the switching component is controlled based on a voltage between high-impedance control and control-reference nodes of the switching component to determine an amount of current that is permitted to flow between the first and second nodes. The impedance transformer includes a positive input node electrically connected to one of the first and second nodes based on AC voltage swings, a negative input node, a positive output node electrically connected to the high-impedance control node, and a negative output node, and which senses an AC voltage swing derived from the AC input voltage with the positive input node and the negative input node, and provides an AC voltage swing between the high-impedance control and control-reference nodes that is greater than the AC voltage swing derived from the AC input voltage.
SAND ART SIMULATION SYSTEM AND METHOD
(2015-07-09)
CHEN Peng-Yu
;
WONG Sai-Keung
;
TSAI Wen-Hsiang
The present invention provides a sand art simulation system and method, which transfers an image into sand art. Analyze contour lines and feature points of objects in the image to find out which contour line can be drawn at the same time. Divide the image into a plurality of blocks, and analyze sand spilling ways at each block. Simulate sand floating in the air, moving and heaping to make a sand-spread plane. Then draw the contour lines on the sand-spread plane to show the sand art of the image.
MOTOR GENERATOR
(2015-07-09)
HU Jwu-Sheng
;
SHEN Te-Yang
The present invention provides a motor generator, and the motor generator comprises a permeability structure, a bearing, a hollow rotating shaft, a ringed clip and a rotatable guiding structure. The permeability structure comprises a primary permeability unit and a secondary permeability unit wherein the second permeability unit is stacked with the first permeability unit along an axial air-gap to form a symmetrical structure having a hollow shaft. The bearing is disposed inside the hollow shaft of the permeability structure. The hollow rotating shaft is passed through the hollow shaft of the permeability structure and disposed at another side of the bearing with respect to the permeability structure. The ringed clip is used for fixing the bearing and the hollow rotating shaft. The rotatable guiding structure is disposed inside the hollow rotating shaft for providing power source and transmitting signals.
A 65-77 GHz low power, meander-type transmission line CMOS low-noise amplifier
(2015-07-10)
Huang, Zhe-Yang
;
Chen, Chun-Chieh
;
Hung, Chung-Chih
;
電機資訊學士班
;
Undergraduate Honors Program of Electrical Engineering and Computer Science
A 65-77 GHz low power, meander-type transmission line CMOS low-noise amplifier for E-band millimetre-wave communication using 90 nm MS/RF CMOS process is demonstrated. The low-noise amplifier consists of multi-stage cascaded common-source amplifiers with optimized noise figure, power gain, and power consumption. The LNA achieves 11.7 dB power gain, 5.5 dB noise figure, and 17.7 mW power consumption. The meander-type transmission line circuit design is adopted to reduce chip area; the total transmission line area in LNA is only 0.024 mm(2).
利用多攝影機自動偵測與追蹤多目標的方法及系統
(2015-07-11)
黃敬群
;
王聖智
一種利用多攝影機偵測與追蹤多目標之方法，包含：(a)以一目標偵測演算法分析多個攝影機場景之偵測結果，用以產生複數個分析資料；(b)利用貝士(Bayesian)架構整合該等分析資料以建立一目標偵測機率(TDP)分佈；以及(c)同時自動偵測與追蹤在該等攝影機場景之監控區域中之複數個移動目標；其中，該監視區係由所有攝影機的重疊視野所決定。
應用複數攝影裝置之物件定位方法
(2015-07-11)
羅國華
;
莊仁輝
;
林泓宏
一種應用複數攝影裝置之物件定位方法，包含：於複數攝影畫面中任一者產生至少一二維取樣線(line sample)，其中各該等攝影畫面具有一消失點以及至少一前景(foreground)區域，該二維取樣線由該消失點所射出，並通過該前景區域；建構複數三維取樣線，其中各該等三維取樣線是根據該等攝影畫面之任二者中任一組成對之該二維取樣線，於複數三維參考平面其中之一上建構，各該等三維取樣線直立於複數參考平面；以及將由該等攝影裝置所建構出的該等三維取樣線，透過計算進行一物件群組區分程序以取得一物件群組數目，以根據該物件群組數目決定一前景視訊物件之一三維位置。
資料偵測系統
(2015-07-11)
林盈達
;
李佳穎
;
張育妮
;
徐鵬凱
;
賴源正
一種資料偵測系統，係包括：複數個偵測單元，係分別以二元偵測機制、三元偵測機制或連續值偵測機制進行資料偵測，其中，該複數個偵測單元係形成循序架構，以使該複數個偵測單元之一者的偵測結果輸入至該複數個偵測單元之另一者來進行相同的資料偵測，且其中，該循序架構係再次對同一資料進行相同或不同精細程度之偵測。
蛋白質電晶體裝置
(2015-07-11)
黃國華
;
洪孟燕
;
陳昱勳
一種蛋白質電晶體裝置，包括：一電晶體，具有一汲極電極、一源極電極及一閘極電極，且該汲極電極與該源極電極之間具有一奈米通道；至少二奈米金粒子，分別設於該汲極電極及該源極電極上，將一第一抗體分子通過該奈米通道自組裝結合至該二奈米金粒子上，據以形成一分子接點；及一量子點，其接合一第二抗體分子並鍵結於該分子接點上。
液晶感測器及用於檢測生物分子的方法
(2015-07-11)
李偉
;
李孟娟
;
孫士弘
;
蘇慧汶
一種液晶感測器，包含：一第一單元，包括一第一基板，及一形成於該第一基板一表面的第一配向膜；一第二單元，與該第一單元間隔且相對應設置並包括一第二基板，及一與該第一配向膜間隔且相對應設置並形成於該第二基板一表面的第二配向膜，其中，該第二配向膜的一表面具有親水性；一液晶層，形成於該第一配向膜與該第二配向膜之間且包括一向列型液晶組份，其中，該向列型液晶組份於20~25℃及波長589nm下所測得的雙折射率△n 範圍為大於0.2至小於0.4；以及一待測物；其中，該第二配向膜能與該待測物結合而使該待測物固定於該第二配向膜具有親水性的表面，以及當該待測物中含有生物分子時，與該生物分子接觸的向列型液晶組份的位向會異於與該生物分子未接觸的向列型液晶組份的位向。
使用擬隨機碼控制功率電晶體導通及關閉時序隨機延遲的裝置
(2015-07-11)
曾煜輝
;
蘇朝琴
;
何盈杰
;
林庭佑
;
吳嘉哲
一種使用擬隨機碼控制功率電晶體導通及關閉時序隨機延遲的裝置，其功率電晶體係由複數個功率電晶體子元件組成，包含：一擬隨機碼產生器；一時序控制信號產生器，係產生一導通或關閉控制信號；一時脈信號產生器，係電氣性連接該擬隨機碼產生器之時脈輸入；一時序延遲控制器，係電氣性連接該擬隨機碼產生器、該時序控制信號產生器及該複數個功率電晶體子元件；其中，該擬隨機碼產生器係控制該時序延遲控制器，使經過該時序延遲控制器之該時序控制信號產生器之導通或關閉控制信號產生隨機延遲之效果後，再輸出至複數個功率電晶體子元件。
電阻式隨存記憶體之製作方法
(2015-07-11)
曾俊元
;
王聖裕
;
蔡承翰
一種電阻式隨存記憶體之製作方法，包含：(a)於一基材上形成一第一電極；(b)於該第一電極上以一175℃至225℃的製程溫度形成一氧化鋯之可變電阻層；及(c)於該可變電阻層上形成一Ti的第二電極；其中，該步驟(b)之可變電阻層的形成是經由濺鍍技術來完成；其中，相較於在一250℃之製程溫度下所製得之氧化鋯之可變電阻層，該步驟(b)在該175℃至225℃之製程溫度下所製作的氧化鋯之可變電阻層於寫入態與抹除態之間的靜態電阻轉換循環次數，能在+1.5V至-2.5V之直流電壓與10次/V之收集頻率的測試條件下，至少提升至6800次。
具頻帶截止功能之超寬頻天線
(2015-07-11)
鍾世忠
;
莊肇堂
一種具頻帶截止功能之超寬頻天線，包括：一上層非均勻式短路金屬貼片，其係與一訊號傳輸段連接；一中間層金屬輻射貼片，其係電性連接至該上層非均勻式短路金屬貼片；以及一下層金屬貼片，其包含有一接地金屬墊、及一耦合開路/短路殘段，該耦合開路/短路殘段係包含有一開路殘段、及一短路殘段，該短路殘段係電性連接至該中間層金屬輻射貼片；其中，該上層非均勻式短路金屬貼片之等效電路係為一並聯LC共振器，該耦合開路/短路殘段之等效電路係為一串聯LC共振器，該上層非均勻式短路金屬貼片之共振頻率係等同於該耦合開路/短路殘段之共振頻率，以使該上層非均勻式短路金屬貼片與該耦合開路/短路殘段組成二階帶拒濾波器。
具有增益校正之鎖相迴路、用於鎖相迴路之增益量測方法、校正方法及抖動量測方法
(2015-07-11)
陳巍仁
;
莊書瑾
一種用於鎖相迴路之振盪器增益量測方法，該鎖相迴路包括由迴路濾波器、振盪器和計數器所組成之迴授相位積分路徑、由和差調變器和累加器所組成之參考相位積分路徑、以及比較該迴授相位積分路徑和該參考相位積分路徑的輸出之相位量化器，該用於鎖相迴路之振盪器增益量測方法係包括以下步驟：(1)於該振盪器的輸入端提供一變化碼；(2)依據該變化碼使該參考相位積分路徑輸出多餘參考相位資訊，並使該迴授相位積分路徑輸出多餘迴授相位資訊；以及(3)根據該多餘參考相位資訊和該多餘迴授相位資訊，獲得該振盪器之估計增益資訊。
Going beyond 4 Gbps data rate by employing RGB laser diodes for visible light communication
(2015-07-13)
Janjua, Bilal
;
Oubei, Hassan M.
;
Retamal, Jose R. Duran
;
Ng, Tien Khee
;
Tsai, Cheng-Ting
With increasing interest in visible light communication, the laser diode (LD) provides an attractive alternative, with higher efficiency, shorter linewidth and larger bandwidth for high-speed visible light communication (VLC). Previously, more than 3 Gbps data rate was demonstrated using LED. By using LDs and spectral-efficient orthogonal frequency division multiplexing encoding scheme, significantly higher data rates has been achieved in this work. Using 16-QAM modulation scheme, in conjunction with red, blue and green LDs, data rates of 4.4 Gbps, 4 Gbps and 4 Gbps, with the corresponding BER/SNR/EVM of 3.3 x 10(-3)/15.3/17.9, 1.4 x 10-3/16.3/15.4 and 2.8 x 10(-3)/15.5/16.7 were obtained over transmission distance of similar to 20 cm. We also simultaneously demonstrated white light emission using red, blue and green LDs, after passing through a commercially available diffuser element. Our work highlighted that a tradeoff exists in operating the blue LDs at optimum bias condition while maintaining good color temperature. The best results were obtained when encoding red LDs which gave both the strongest received signal amplitude and white light with CCT value of 5835K. (C) 2015 Optical Society of America
Dynamic integral imaging display with electrically moving array lenslet technique using liquid crystal lens
(2015-07-13)
Jen, Tai-Hsiang
;
Shen, Xin
;
Yao, Gang
;
Huang, Yi-Pai
;
Shieh, Han-Ping D.
Integral imaging (InIm) has been widely investigated for threedimensional (3-D) display applications. Aliasing due to the lenslet arrays is one of the limitations of InIm displays. In this paper, we propose a dynamic InIm display using electrically movable liquid crystal (LC) lens array to implement the moving array lenslet technique (MALT) and to eliminate the multifacet phenomenon in the 3-D images. The improvement of the viewing quality of dynamic InIm display is experimentally verified. (C) 2015 Optical Society of America
High-power noise-like pulse generation using a 1.56-mu m all-fiber laser system
(2015-07-13)
Lin, Shih-Shian
;
Hwang, Sheng-Kwang
;
Liu, Jia-Ming
;
光電系統研究所
;
Institute of Photonic System
We demonstrated an all-fiber, high-power noise-like pulse laser system at the 1.56-mu m wavelength. A low-power noise-like pulse train generated by a ring oscillator was amplified using a two-stage amplifier, where the performance of the second-stage amplifier determined the final output power level. The optical intensity in the second-stage amplifier was managed well to avoid not only the excessive spectral broadening induced by nonlinearities but also any damage to the device. On the other hand, the power conversion efficiency of the amplifier was optimized through proper control of its pump wavelength. The pump wavelength determines the pump absorption and therefore the power conversion efficiency of the gain fiber. Through this approach, the average power of the noise-like pulse train was amplified considerably to an output of 13.1 W, resulting in a power conversion efficiency of 36.1% and a pulse energy of 0.85 mu J. To the best of our knowledge, these amplified pulses have the highest average power and pulse energy for noise-like pulses in the 1.56-mu m wavelength region. As a result, the net gain in the cascaded amplifier reached 30 dB. With peak and pedestal widths of 168 fs and 61.3 ps, respectively, for the amplified pulses, the pedestal-to-peak intensity ratio of the autocorrelation trace remains at the value of 0.5 required for truly noise-like pulses. (C) 2015 Optical Society of America
Shape and Confinement Effects of Various Terminal Siloxane Groups on Supramolecular Interactions of Hydrogen-Bonded Bent-Core Liquid Crystals
(2015-07-14)
Chiang, I-Hung
;
Chuang, Wei-Tsung
;
Lu, Chia-Lin
;
Lee, Ming-Tao
;
Lin, Hong-Cheu
To investigate the shape and confinement effects of the terminal siloxane groups on the self-assembled behavior of molecular arrangements in hydrogen-bonded (H-bonded) bent-core complexes, four H-bonded bent-core complexes Si, P1, C4, and P8 with string-, ring-, and cagelike siloxane termini (i.e., linear siloxane unit -Si-O-Si-O-Si, cyclic siloxane unit (Si-O)(4), and silsesquioxane unit PUSS, respectively) were synthesized and investigated. By X-ray diffraction measurements, different types of SmCG (B8) phases and leaning angles were controlled by the shape effect of the string- and cage-like siloxane termini for Si and P1 (with only one arm of H-bonded bent-core), respectively. In addition, the confinement effect of Pi, C4, and P8 (accompanied by increasing the numbers of attached H-bonded bent-core arms) resulted in higher transition temperatures and the diminishing of mesophasic ranges (even the disappearance of mesophase in P8). Moreover, AFM images showed the bilayer smectic CG phases of Si and P1 were aligned to reveal highly ordered thread-like structures by a DC field. By spontaneous polarization measurements within the mesophasic ranges, Si and P1 showed ferroelectric transitions but C4 displayed antiferroelectricity. Finally, the electro-optical performance of B8 phases could be optimized through binary mixtures of Si and P1, and a well aligned modulated ribbon phase could be formed via specific molar ratios of the binary mixtures.