Browsing by Issue Date, starting with "2015-10-20"

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Magnetic Nanoparticle-Based Platform for Characterization of Shiga-like Toxin 1 from Complex Samples
(2015-10-20)
Kuo, Fang-Yin
;
Chang, Bo-Yao
;
Wu, Ching-Yi
;
Mong, Kwok-Kong Tony
;
Chen, Yu-Chie
Foodbome illness outbreaks resulting from contamination of Escherichia call O157:H7 remain a serious concern in food safety. E. coli O157:H7 can cause bloody diarrhea, hemolytic uremic syndrome, or even death. The pathogenicity of E. coli O157:H7 is mainly caused by the expression of Shiga-like toxins (SLTs), i.e., SLT-1 and SLT-2. SLTs are pentamers composed of a single A and five B subunits. In this study, we propose a magnetic nanoparticle (MNP)-based platform to rapidly identify SLT-1 from the complex cell lysate of E. coli O157:H7. The core of the MNPs is made of iron oxide, whereas the surface of the core is coated with a thin layer of alumina (Fe3O4@Al2O3 MNPs). The Fe3O4@Al2O3 MNPs are functionalized with pigeon ovalbumin (POA), which contains Gal-alpha(1 -> 4)-Gal-beta(1 -> 4)-GlcNAc termini that can bind SLT-1B selectively. Furthermore, POA is a phosphate protein. Thus, it can be easily immobilized on the surface of the Fe3O4@Al2O3 MNPs through aluminum phosphate chelation under microwave heating within 1.5 min. The generated POA-Fe3O4@Al2O3 MNPs are capable of effectively enriching SLT-1B from complex cell lysates simply by pipetting 20 mu L, of the sample in and out of the tip in a vial for similar to 1 min. To release SLT-1 from the MNPs, Gal-alpha(1 -> 4)-Gal disaccharides were used for displacement. The released target species are sufficient to be identified by matrix-assisted laser desorption/ionization mass spectrometry. Although the sample volume used in this approach is small (20 mu L) and the enrichment time is short (1 mm), the selectivity of this approach toward SLT-1B is quite good. We have demonstrated the effectiveness of this approach for rapid determination of the presence of SLT-1 from complex cell lysates and ham/juice samples based on the detection of SLT-1B.
Theory of Triplet Excitation Transfer in the Donor-Oxygen-Acceptor System: Application to Cytochrome b(6)f
(2015-10-20)
Petrov, Elmar G.
;
Robert, Bruno
;
Lin, Sheng Hsien
;
Valkunas, Leonas
;
交大名義發表
Theoretical consideration is presented of the triplet excitation dynamics in donor-acceptor systems in conditions where the transfer is mediated by an oxygen molecule. It is demonstrated that oxygen may be involved in both real and virtual intramolecular triplet-singlet conversions in the course of the process under consideration. Expressions describing a super-exchange donor-acceptor coupling owing to a participation of the bridging twofold degenerate oxygen\'s virtual singlet state are derived and the transfer kinetics including the sequential (hopping) and coherent (distant) routes are analyzed. Applicability of this theoretical description to the pigment-protein complex cytochrome b(6)f, by considering the triplet excitation transfer from the chlorophyll a molecule to distant beta-carotene, is discussed.
Effect of anions on the oxidation and reduction of hydrogen peroxide on the gold nanoparticle-deposited carbon fiber paper electrode
(2015-10-20)
Lin, Chen-Han
;
Wei, Lan-Yi
;
Lee, Jhao-Hong
;
Lien, Chun-Lung
;
Lu, Chung-Hsiang
The nanostructured gold has been shown to catalyze the oxidation of hydrogen peroxide (H2O2), an important analyte for clinical diagnosis. However, little is known about the effect of anions on its catalytic activity. In this study the gold nanoparticles (AuNP) of average size of 30-80 nm were electrodeposited on the carbon fiber paper (CFP) electrode to explore the effect of anions, such as phosphate, sulfate, nitrate, acetate, chloride and hydroxide ions, on the AuNP-catalyzed H2O2-oxidation. In phosphate solution the AuNP-deposited CFP (AuNP/CFP) exhibited high catalytic activity to H2O2. However, the catalytic activity of AuNP was severed blocked in solutions containing chloride, sulfate, nitrate, and acetate ions. Although hydroxide was shown to facilitate the catalysis of AuNP, the oxidation of H2O2 was greatly interfered by the gold oxide formation in 0.05 M NaOH. A strong dipole moment between adsorbed anions, such sulfate, nitrate and acetate, and AuNP is suggested to block the access of H2O2 molecules to the surface of AuNPs. This postulation is demonstrated by the finding that the electrochemical active surface area of AuNP/CFP is 0.90 +/- 0.02 cm(2), 0.79 +/- 0.08 cm(2), 0.66 +/- 0.09 cm(2), 0.45 +/- 0.04 cm(2), 0.42 +/- 0.08 cm(2) and 0.15 +/- 0.08 cm(2), in 0.05 M hydroxide, phosphate, bicarbonate, nitrate, acetate and sulfate solutions, respectively. These results indicate that the microenvironment near the surface of nanostructured Au is important to determine the catalytic activity of Au to H2O2. (C) 2015 Elsevier Ltd. All rights reserved.
交大e-News第196期-交通大學X宣捷生物科技共創幹細胞大未來
(2015-10-20)
國立交通大學秘書室
;
Secretariat
Trap-assisted tunneling in aluminum-doped ZnO/indium oxynitride nanodot interlayer Ohmic contacts on p-GaN
(2015-10-21)
Ke, Wen-Cheng
;
Lee, Fang-Wei
;
Yang, Cheng-Yi
;
Chen, Wei-Kuo
;
Huang, Hao-Ping
This study developed an Ohmic contact formation method for a ZnO:Al (AZO) transparent conductive layer on p-GaN films involving the introduction of an indium oxynitride (InON) nanodot interlayer. An antisurfactant pretreatment was used to grow InON nanodots on p-GaN films in a RF magnetron sputtering system. A low specific contact resistance of 1.12 x 10(-4) Omega cm(2) was achieved for a sample annealed at 500 degrees C for 30 s in nitrogen ambient and embedded with an InON nanodot interlayer with a nanodot density of 6.5 x 10(8) cm(-2). By contrast, a sample annealed in oxygen ambient exhibited non-Ohmic behavior. X-ray photoemission spectroscopy results showed that the oxygen vacancy (V-o) in the InON nanodots played a crucial role in carrier transport. The fitting I-V characteristic curves indicated that the hopping mechanism with an activation energy of 31.6 meV and trap site spacing of 1.1 nm dominated the carrier transport in the AZO/InON nanodot/p-GaN sample. Because of the high density of donor-like oxygen vacancy defects at the InON nanodot/p-GaN interface, positive charges from the underlying p-GaN films were absorbed at the interface. This led to positive charge accumulation, creating a narrow depletion layer; therefore, carriers from the AZO layer passed through InON nanodots by hopping transport, and subsequently tunneling through the interface to enter the p-GaN films. Thus, AZO Ohmic contact can be formed on p-GaN films by embedding an InON nanodot interlayer to facilitate trap-assisted tunneling. (C) 2015 AIP Publishing LLC.
閘極堆疊結構及包含其之金屬氧化物半導體元件及閘極堆疊結構之製造方法
(2015-10-21)
林岳欽
;
張翼
;
莊庭維
一種電晶體之閘極堆疊結構，包含：一基板；一半導體層，設置於該基板上；一閘極介電層，設置於該半導體層上，其中該閘極介電層係包含由氧化鑭(La2O3)、氧化鉿(HfO2)及包含氧化鑭/氧化鉿之該半導體層之一上表面層所組成之複合氧化物層；以及一閘極電極層，設置於該閘極介電層上。
Three-Dimensional Heterostructures of MoS2 Nanosheets on Conducting MoO2 as an Efficient Electrocatalyst To Enhance Hydrogen Evolution Reaction
(2015-10-21)
Nikam, Revannath Dnyandeo
;
Lu, Ang-Yu
;
Sonawane, Poonarn Ashok
;
Kumar, U. Rajesh
;
Yadav, Kanchan
Molybdenum disulfide (MoS2) is a promising catalyst for hydrogen evolution reaction (HER) because of its unique nature to supply active sites in the reaction. However, the low density of active sites and their poor electrical conductivity have limited the performance of MoS2 in HER. In this work, we synthesized MoS2 nanosheets on three-dimensional (3D) conductive MoO2 via a two-step chemical vapor deposition (CVD) reaction. The 3D MoO2 structure can create structural disorders in MoS2 nanosheets (referred to as 3D MoS2/MoO2), which are responsible for providing the superior HER activity by exposing tremendous active sites of terminal disulfur of S-2(-2) (in MoS2) as well as the backbone conductive oxide layer (of MoO2) to facilitate an interfacial charge transport for the proton reduction. In addition, the MoS2 nanosheets could protect the inner MoO2 core from the acidic electrolyte in the HER. The high activity of the as-synthesized 3D MoS2/MoO2 hybrid material in HER is attributed to the small onset overpotential of 142 mV, a largest cathodic current density of 85 mA cm(-2), a low Tafel slope of 35.6 mV dec(-1), and robust electrochemical durability.
使用電池通道傳輸的電池管理設備
(2015-10-21)
曾煜輝
;
蘇朝琴
;
陳昶志
;
何盈杰
一種使用電池通道傳輸的電池管理設備，包含：一電池通道傳輸網路，係由複數個電池集所建構而成；一電池電量管理控制單元，係連接該電池通道傳輸網路；複數個通信設備，係連接該電池通道傳輸網路，每一通信設備係對應一電池集；複數個電池電量監測單元，每一電池電量監測單元係電性連接一電池集，並電性連接該電池集所對應之通信設備，藉以監測該電池集之電量，並利用該對應之通信設備，將監測之結果經由該電池通道傳輸網路傳送至該電池電量管理控制單元；複數個電池充放電控制單元，每一電池充放電控制單元係電性連接一電池集，並電性連接該電池集所對應之通信設備，藉以利用該對應之通信設備，經由該電池通道傳輸網路接收該電池電量管理控制單元所傳送之一電池充放電控制信號，並因應該電池充放電控制信號之內容，對該電池集進行一充電或一放電動作；複數個電池通道收發實體連接裝置，係電性連接該電池通道傳輸網路，且該電池電量管理控制單元與每一通信設備係分別經由一電池通道收發實體連接裝置連接至該電池通道傳輸網路。
施工預算書、資訊化模型及施工項目數量之產生方法
(2015-10-21)
王維志
;
徐霈元
;
朱美憶
;
王琨淇
一種施工預算書產生方法，包含下列步驟：提供一相對應於一公共工程經費估價系統之工程工項名稱與編碼規則次序之一工項資料庫；取得一主體工程工項，其中該主體工程工項對應該工項資料庫之一工程工項名稱與一編碼規則次序；取得一非主體工程工項，其中該非主體工程工項對應該工項資料庫之一工程工項名稱與一編碼規則次序；以及根據該主體工程工項、該非主體工程工項、該工項資料庫及該公共工程經費估價系統，而產生一施工預算書。
頭戴式人眼追蹤系統
(2015-10-21)
歐陽盟
;
邱俊誠
;
黃庭緯
;
胡俊誠
;
莊竣崴
一種頭戴式人眼追蹤系統，包括：一第一光源，發出一第一光束以照亮一使用者的一第一眼；一第一瞳孔影像擷取裝置，配置在來自該第一眼所反射的該第一光束的傳遞路徑上，以擷取來自該第一眼的一第一瞳孔影像；一第一環境影像擷取裝置，適於擷取該使用者前方的一第一環境影像；一第二環境影像擷取裝置，適於擷取該使用者前方的一第二環境影像；一固定裝置，配置於該使用者的頭上，以將該第一光源、該第一瞳孔影像擷取裝置、該第一環境影像擷取裝置以及該第二環境影像擷取裝置固定於該使用者的該第一眼的週圍；以及一影像辨別系統，適於將該第一環境影像以及該第二環境影像其中至少一者與該第一瞳孔影像進行映對，以辨別出該使用者注視的位置。
可攜式二維血氧顯影裝置
(2015-10-21)
方偉騏
;
陳殿河
;
康適
;
吳世揚
;
鄭敬儒
一種可攜式二維血氧顯影裝置，包括：前端偵測器，係具有複數個光源及複數個感測器，該複數個光源發送檢測光線至一待測物體，以由該複數個感測器感測該檢測光線經該待測物體反射後的光源強度，該前端偵測器包括數位多工器及類比解多工器，係分別用以控制該複數個光源及該複數個感測器；分析處理器，係接收該前端偵測器所偵測到之該光源強度，並分析該光源強度以依據一血氧濃度分布演算法產生該待測物體之各區域組織的血氧濃度分布資訊；以及影像重建器，係依據該分析處理器所產生之血氧濃度分布資訊進行影像重建，並產生以色階差異表示該待測物體之各區域組織之血氧飽和濃度的顯影資訊，其中，該複數個光源及該複數個感測器非同時啟動運作，而是依據偵測順序及感測範圍，通過該數位多工器及該類比解多工器以啟動該感測範圍內的至少一光源及其周邊之四個感測器，且該偵測順序及該感測範圍係由該分析處理器來決定控制。
Relationship between Polycystic Ovarian Syndrome and Subsequent Gestational Diabetes Mellitus: A Nationwide Population-Based Study
(2015-10-21)
Pan, Mei-Lien
;
Chen, Li-Ru
;
Tsao, Hsiao-Mei
;
Chen, Kuo-Hu
;
機械工程學系
Objective This nationwide population-based study aims to explore the relationship between polycystic ovarian syndrome (PCOS) and subsequent gestational diabetes mellitus (GDM). Methods Data from 1998-2012 Taiwan National Health Insurance Research Database were used for this study. ICD9-CM codes 256.4X and 648. X were used separately for the diagnoses of PCOS and GDM, which were further confirmed by records of blood tests or ultrasonography to ensure the accuracy of the diagnoses. Women diagnosed at < 15 or > 45 years of age, and those diagnosed with overt diabetes mellitus or GDM prior to PCOS were excluded. During pregnancy, each woman with a previous diagnosis of PCOS was age-matched to 10 women without PCOS. Odds ratios (ORs) for risk of GDM were calculated by logistic regression analysis with adjustment for economic status and co-morbidities. Results Among 7,629 eligible women with a valid PCOS diagnosis, 3,109 (42.87%) had subsequent pregnancies. GDM occurred frequently among women with a history of PCOS as compared to those without PCOS (20.46% vs. 10.54%, p< 0.0001). Logistic regression analysis revealed that PCOS was associated with GDM (adjusted OR = 2.15; 95% CI: 1.96-2.37). Among 3,109 affected patients, 1,160 (37.31%) had used medications for PCOS and 261 (8.39%) were treated with an oral hypoglycemic agent (OHA). There was no significant difference in development of GDM between the medication and no medication sub-groups (p> 0.05). If not used after conception, OHAs did not reduce the risk of GDM (adjusted OR = 1.20; 95% CI: 0.88-1.62). Conclusions A history of PCOS is a significant and independent risk factor for development of GDM. Medication for PCOS or pre-pregnancy use of OHAs does not reduce the risk of GDM. When at-risk women become pregnant, they require closer surveillance for maternal and fetal well-being, and should follow a strict diet and adhere to weight gain control to avoid obstetric complications due to GDM.
照明系統以及投影裝置
(2015-10-21)
潘瑞文
;
施濟濠
一種照明系統，包括：至少一同調光源，適於發出一同調光束；一光均勻化元件，配置於該同調光束的傳遞路徑上，該光均勻化元件具有一入光側以及一出光側，且該入光側位於該同調光源與該出光側之間；一第一擴散元件，配置於該入光側，且在平行於該入光側的一平面上來回震盪，該同調光束通過該第一擴散元件後進入該光均勻化元件；以及一第二擴散元件，配置於該出光側，且來自該光均勻化元件的該同調光束通過該第二擴散元件，其中該第一擴散元件的震盪頻率落在50Hz至600Hz的範圍內。
雙旋流混合火箭引擎
(2015-10-21)
陳彥升
;
吳明仁
;
吳宗信
;
賴冠融
;
林哲緯
一種雙旋流混合火箭引擎，包括本體和連接本體尾部的噴嘴，其中所述本體內部包括一第一碟形燃燒室、一第二碟形燃燒室以及連通該該第一以及第二碟形燃燒室軸部的中央燃燒室，其中該第一碟形燃燒室以及該第二碟形燃燒室係呈軸向排列；該第一以及第二碟形燃燒室的圓周內壁面上分別地設置有多個氧化劑噴注嘴用以噴注氧化劑；其中，該第一以及第二碟形燃燒室係為相鄰的，且該第一碟形燃燒室的該氧化劑噴注嘴所噴注出之氧化劑方向與該第二碟形燃燒室的該氧化劑噴注嘴所噴注出之氧化劑方向係為相反的以使在第一碟形燃燒室中的氧化劑以及在第二碟形燃燒室中的氧化劑分別形成順時針的旋流以及逆時針的旋流。
Angiotensin Receptor Blockers Decrease the Risk of Major Adverse Cardiovascular Events in Patients with End-Stage Renal Disease on Maintenance Dialysis: A Nationwide Matched-Cohort Study
(2015-10-21)
Tzeng, Nian-Sheng
;
Yin, Yun-Ju
;
Li, Chien-Hsun
;
Chen, Hung-An
;
Chiu, Shih-Hsiang
Background Major adverse cardiovascular events (MACE) cause the leading cause of morbidity and mortality in patients with end-stage renal disease (ESRD) on maintenance Hemodialysis (HD) or peritoneal dialysis (PD). Many randomized-controlled trials (RCTs) have proved that angiotensin receptor blockers (ARBs) can reduce the risk of MACE in the people with normal or impaired kidney function without dialysis. This study seeks to clarify whether ARBs therapy could also attenuate this risk in patients with ESRD on maintenance dialysis. Materials and Methods The National Health Research Institute provided a database of one million random subjects for the study. A random sample was taken of 1800 patients >= 18 years y/o with ESRD on dialysis without a history of MACE and use of ARBs within 6-months prior to enrollment. Cox proportional hazard regression analysis was used to identify the risk factors and compute the hazard ratios accompanying 95% confidence intervals. Results In these 1800 patients, 1061 had never used ARBs, while 224 had used them for 1-90 days, and 515 had used them for more than 90 days. We found that ARBs significantly decrease the incidences of acute myocardial infarctions (AMI), coronary artery diseases (CAD) requiring coronary stent or percutaneous transluminal coronary angioplasty (PTCA), peripheral artery disease (PAD) requiring percutaneous transluminal angioplasty (PTA), and acute stroke. Cumulative prescription days of ARBs beyond 365-760 days or more were found to be negatively correlated with incidence of MACEs. For patients with dual comorbidity (i.e., mellitus and hyperlipidemia), 91-365 cumulative prescription days might also attenuate the risk. Conclusions For patients on maintenance dialysis, the use of ARBs could significantly attenuate the risk of major cardiovascular events: AMI, acute stroke, and PAD requiring PTA.
奈米級複合高分子顯影劑及藥物載體
(2015-10-21)
陳三元
;
黃信揚
;
胡尚秀
一種合成複合磁性奈米超音波微泡之方法，包含下列步驟：將一磁性奈米粒子溶於一有機溶劑之中以形成一有機相混成溶液；將一水溶性高分子和一溫度敏感型高分子進行一特定比例的摻雜以形成一水相溶液；將該有機相混成溶液和該水相溶液在室溫下一起震盪，以形成一混合物；以及在一溫度梯度之內，對該混合物先進行一升溫過程後再進行一降溫過程，在該降溫過程之後，將一氣體打入該混合物，使該混合物自組裝而形成該複合磁性奈米超音波微泡，其中該氣體包括全氟化物(Perfluoropentane,PFP,C5 F12 )和六氟化硫(SF6 )的其中之一，該溫度敏感型高分子包括一普朗尼克(Pluronic)F68和一普朗尼克F127的其中之一，該水溶性高分子包括一聚乙烯酸(Polyacrylic Acid,PAA)和一聚乙烯醇(Polyvinyl alcohol,PVA)的其中之一，該有機溶劑包括一二氯甲烷，該磁性奈米粒子包括一四氧化三鐵(Fe3 O4 )、一三氧化二鐵(Fe2 O3 )、一鈷鐵氧化物(CoFe2 O4 )、一錳鐵氧化物(MnFe2 O4 )和一氧化釓(Gd2 O3 )的其中之一。
VISIBLE LIGHT COMMUNICATION METHOD
(2015-10-22)
SUNG Jiun-Yu
;
YEH Chien-Hung
;
CHOW Chi-Wai
A visible light communication method. Firstly, a plurality of binary logic streams is sequentially received and a serial-to-parallel conversion is performed on them to obtain a plurality of binary signal sets corresponding to each binary logic stream. Then, all the binary signal sets are respectively mapped to obtain the first OFDM symbols in frequency domain. The first OFDM symbols are respectively transformed into the second OFDM symbols in time domain. Then, a parallel-to-serial conversion is performed on the second OFDM symbols. Adequate cyclic prefix is added in each of the second OFDM symbols. Next, the relative intensity of each of the second OFDM symbols is regulated, and then a digital-to-analog conversion is performed on the second OFDM symbols to obtain analog electrical signals. Finally, visible lights respectively corresponding to the analog electrical signals are generated.
HIGH ENERGY DENSITY ASYMMETRIC PSEUDOCAPACITOR AND METHOD OF MAKING THE SAME
(2015-10-22)
Tseng Tseung-Yuen
;
Hung Chung-Jung
;
Lin Pang
A high energy density asymmetric pseudocapacitor includes a cathode plate, an anode plate, and a separator. The cathode plate includes a first conductive substrate and a porous cathode film formed on the first conductive substrate. The porous cathode film includes a carbon nano-tube network and a plurality of composite flakes. Each of the composite flakes contains graphene, a transition metal compound and carbon nano-tubes. The anode plate includes a second conductive substrate and an anode film formed on the second conductive substrate. The anode film contains graphene and carbon nano-tubes.
Photoisomerization Reaction Mechanisms of o-Nitrophenol Revealed by Analyzing Intersystem Crossing Network at the MRCI Level
(2015-10-22)
Xu, Chao
;
Yu, Le
;
Zhu, Chaoyuan
;
Yu, Jianguo
;
應用化學系分子科學碩博班
6SA-CASSCF(10, 10) /6-31G (d, p) and MRCl/cc-pVDZ methods were performed to probe photoisomerization reaction mechanisms of o-nitrophenol. Two low-lying singlet electronic states (S-0 and S-1) and two low-lying triplet electronic states (T-1 and T-2) were found to weave an intersystem crossing network in which a dominant stepwise photoisomerization provides a very efficient reaction pathway; the reaction takes place in the wide region of crossing seam-surface woven by S-1 and T-1 states first, followed by T-1 and S-0 states. Both intersystem crossing regions show strong spin orbital coupling in the order of 40 wavenumbers. All nitro and aci-nitro isomers and transition states on four electronic potential energy surfaces are calculated along with analysis of both dominant and subdominant relaxation pathways, especially weak spin-orbital coupling (similar to 10 wavenumbers) between T-2 and S-1 states and effective conical intersection between T-2 and T-1 states opening a new relaxation pathway S-1 -> T-2 -> T-1.
METHOD AND SYSTEM FOR DYNAMIC INSTANCE DEPLOYMENT OF PUBLIC CLOUD
(2015-10-22)
TING Wei-Chih
;
WANG Jun-Zhe
;
CHEN Chia-Min
;
HUANG Jiun-Long
According to one exemplary embodiment, a method for dynamic instance deployment of public cloud uses a load monitor to obtain a current server deployment, wherein the current server deployment at least includes, for each server of a plurality of servers, an identity information of the server, and a number of current connections of the server, a server instance type of the server, and a located area of the server; and uses a scaling engine to determine whether there is at least one server of the plurality of servers satisfies at least one trigger condition, add the at least one server that satisfies the at least one trigger condition into a server candidate set, and receive an information of a performance cost ratio to perform a server scaling procedure for at least one area according to the server candidate set.