Browsing by Issue Date, starting with "2016-09-19"

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Water-Soluble Dinitrosyl Iron Complex (DNIC): a Nitric Oxide Vehicle Triggering Cancer Cell Death via Apoptosis
(2016-09-19)
Wu, Shou-Cheng
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Lu, Chung-Yen
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Chen, Yi-Lin
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Lo, Feng-Chun
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Wang, Ting-Yin
Nitric oxide (NO) is an important cellular signaling molecule that modulates various physiological activities. Angiogenesis-promoting activities of NO-donor drugs have been explored in both experimental and clinical studies. In this study, a structurally well characterized and water-soluble neutral {Fe-(NO)(2)}(9) DNIC [(S(CH2)(2)OH)(S(CH2)(2)NH3)Fe(NO)(2)] (DNIC 2) was synthesized to serve as a NO-donor species. The antitumor activity of DNIC 2 was determined by MTT assay, confocal imaging, and Annexin-V/PI staining. The IC50 values of DNIC 2 were 18.8, 42.9, and 38.6 mu M for PC-3, SKBR-3, and CRLS866 tumor cells, respectively. Moreover, DNIC 2 promoted apoptotic cell death via activation of apoptosis-associated proteins and inhibition of survival associated proteins. In particular, DNIC 2 treatment suppressed PC-3 tumor growth by 2.34- and 19.3-fold at 7 and 21 days, in comparison with the control group. These results indicate that water-soluble DNIC 2 may serve as a promising drug for cancer therapy.
Synchronized self-mode-locked 1061-nm and 1064-nm monolithic Nd:YAG laser at cryogenic temperatures with two orthogonally polarized emissions: generation of 670 GHz beating
(2016-09-19)
Huang, T. L.
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Sung, C. L.
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Cheng, H. P.
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Cho, C. Y.
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Liang, H. C.
A dual-wavelength self-mode-locked monolithic Nd: YAG laser at 1061 and 1064 nm is realized at cryogenic temperatures. At an incident pump power of 5.5 W, the total output power can reach 2.5 W and the mode-locked pulse width is 29 ps at a pulse repetition rate of 7.75 GHz. The synchronization of the dual-wavelength emissions leads to a beat frequency of 670 GHz in the individual mode-locked pulse. It is further discovered that the laser output consists of two orthogonally polarized components with a central frequency difference of 127 MHz. The central frequency difference between two orthogonal polarizations mainly arises from the external mechanical stress introduced by the copper holder for the laser crystal. (C) 2016 Optical Society of America
Combination of Raman Spectroscopy and Mass Spectrometry for Online Chemical Analysis
(2016-09-20)
Meher, Anil Kumar
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Chen, Yu-Chie
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應用化學系
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Department of Applied Chemistry
Mass spectrometry (MS) and Raman spectroscopy are complementary analytical techniques used to provide information related to chemical structures and functional groups of target analytes. Each instrument provides specific chemical information. If these two analytical tools are coupled online, comprehensive structural information can be simultaneously collected from the analytes of interest without losing any important chemical information. Nevertheless, exploring a suitable interface for coupling of these analytical tools, which are governed with different operation principles, remains challenging. In this study, we used a small piece of tissue paper as an: interface for hyphenating a Raman spectroscope and a mass spectrometer online. The paper played multiroles as sample loading substrate and an emitter to generate electrospray. Furthermore, it can facilitate surface-enhanced Raman spectroscopic analysis to improve analyte signals in Raman spectra. A sample droplet was placed on the tissue paper located close to the laser of the Raman spectroscope and the inlet of mass spectrometer. Raman spectra were first collected by the Raman spectroscope through laser irradiation followed by generation of electrospray on the edge of the paper for MS analysis. Positional isomers were used as model samples to demonstrate the effectiveness of the hyphenated analytical tool in distinguishing isomers. The feasibility of using this Raman-MS hyphenated technique for monitoring chemical reactions online in real time was also investigated.
交大e-News第217期-台德共研多鐵材料鐵酸鉍薄膜獲刊《Nature Communications》
(2016-09-20)
國立交通大學秘書室
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Secretariat
Electrodeposited Fe2TiO5 nanostructures for photoelectrochemical oxidation of water
(2016-09-20)
Lin, Yan-Gu
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Hsu, Yu-Kuei
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Lin, Yu-Chang
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Chen, Ying-Chu
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材料科學與工程學系
Electrodeposition was used to fabricate nanostructured films of Ti-containing hematite for application to the photoelectrochemical (PEC) splitting of water. The morphology and microstructure of Ti-doped hematite were examined with a scanning electron microscope, X-ray diffraction, Raman spectra and X-ray photoelectron spectra. Optical absorption spectra indicated an enhanced light absorbance in Ti-doped hematite. This Ti doping increased the carrier concentration about ten-fold, confirmed with a Mott-Schottky analysis. The prepared Ti-doped hematite showed a photocurrent enhanced four-fold relative to pristine hematite. Synchrotron-based soft X-ray absorption spectra clearly revealed that a local Fe2TiO5 structure in hematite formed a heterojunction, which decreased the accumulation of photogenerated holes and improved the performance. (C) 2016 Elsevier Ltd. All rights reserved.
Electrodeposited Fe2TiO5 nanostructures for photoelectrochemical oxidation of water
(2016-09-20)
Lin, Yan-Gu
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Hsu, Yu-Kuei
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Lin, Yu-Chang
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Chen, Ying-Chu
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材料科學與工程學系
Electrodeposition was used to fabricate nanostructured films of Ti-containing hematite for application to the photoelectrochemical (PEC) splitting of water. The morphology and microstructure of Ti-doped hematite were examined with a scanning electron microscope, X-ray diffraction, Raman spectra and X-ray photoelectron spectra. Optical absorption spectra indicated an enhanced light absorbance in Ti-doped hematite. This Ti doping increased the carrier concentration about ten-fold, confirmed with a Mott-Schottky analysis. The prepared Ti-doped hematite showed a photocurrent enhanced four-fold relative to pristine hematite. Synchrotron-based soft X-ray absorption spectra clearly revealed that a local Fe2TiO5 structure in hematite formed a heterojunction, which decreased the accumulation of photogenerated holes and improved the performance. (C) 2016 Elsevier Ltd. All rights reserved.
Functional Supramolecular Polymers: A Fluorescent Microfibrous Network in a Supramolecular Hydrogel for High-Contrast Live Cell-Material Imaging in 3D Environments
(2016-09-21)
Hsu, Shu-Min
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Wu, Fang-Yi
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Cheng, Hsun
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Huang, Yu-Tang
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Hsieh, Yi-Ru
A new bottom-up strategy based on aromatic peptide amphiphile is developed for a high-contrast visualization of 3D live cell-material imaging-something that has been difficult to achieve previously because of the problems associated with the diffraction of light by the nanosized peptide materials and the aggregation-caused quenching of aggregated pi-conjugated fluorophores in the nanostructures. This study reports an example of a novel supramolecular hydrogelator, naphthaleneimide-phenylalanine (NI-Phe), which forms a self-supporting hydrogel displaying a unique microfibrous network and promising aggregation-induced emission characteristics at pH 7.4. The storage modulus of the NI-Phe gel supports the mass of a cell for 3D cell culturing. This work illustrates a new dopant-free supramolecular approach, complementary to well-established doping procedures that should facilitate the development of live cell imaging in 3D scaffolding materials.
Online monitoring of chemical reactions by polarization-induced electrospray ionization
(2016-09-21)
Meher, Anil Kumar
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Chen, Yu-Chie
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應用化學系
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Department of Applied Chemistry
Polarization-induced electrospray ionization (PI-ESI) is a simple technique for instant generation of gas-phase ions directly from a microliter-sized droplet for mass spectrometric analysis. A sample droplet was placed over a dielectric substrate and in proximity (2-3 mm) to the inlet of a mass spectrometer. Owing to the polarization effect induced by the high electric field provided by the mass spectrometer, the droplet was polarized and the electrospray was generated from the apex of the droplet. The polarization-induced electrospray could last for tens of seconds, which was sufficiently long to monitor fast reactions occurring within few seconds. Thus, we demonstrated the feasibility of using the droplet-based PI-ESI MS for the online monitoring of fast reactions by simply mixing two droplets (5-10 mu L) containing reactants on a dielectric substrate placed in front of a mass spectrometer applied with a high voltage (-4500 V). Schiff base reactions and oxidation reactions that can generate intermediates/products within a few seconds were selected as the model reactions. The ionic reaction species generated from intermediates and products can be simultaneously monitored by PI-ESI MS in real time. We also used this approach to selectively detect acetone from a urine sample, in which acetone was derivatized in situ. In addition, the possibility of using this approach for quantitative analysis of acetone from urine samples was examined. (C) 2016 Elsevier B.V. All rights reserved.
Self-Assembled BiFeO3-epsilon-Fe2O3 Vertical Heteroepitaxy for Visible Light Photoelectrochemistry
(2016-09-21)
Le Thi Quynh
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Chien Nguyen Van
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Bitla, Yugandhar
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Chen, Jhih-Wei
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Thi Hien Do
Self-assembled vertical heterostructure with a high interface-to-volume ratio offers tremendous opportunities to realize intriguing properties and advanced modulation of functionalities. Here, a heterostructure composed of two visible-light photocatalysts, BiFeO3 (BFO) and epsilon-Fe2O3 (epsilon-FO), is designed to investigate its photoelectrochemical performance. The structural characterization of the BFO-FO heterostructures confirms the phase separation with BFO nanopillars embedded in the epsilon-FO matrix. The investigation of band structure of the heterojunction suggests the assistance of photoexcited carrier separation, leading to an enhanced photoelectrochemical performance. The insights into the charge separation are further revealed by means of ultrafast dynamics and electrochemical impedance spectroscopies. This work shows a delicate design of the self-assembled vertical heteroepitaxy by taking advantage of the intimate contact between two phases that can lead to a tunable charge interaction, providing a new confi guration for the optimization of photoelectrochemical cell.
Block Copolymer-Tuned Fullerene Electron Transport Layer Enhances the Efficiency of Perovskite Photovoltaics
(2016-09-21)
Lin, Hsi-Kuei
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Su, Yu-Wei
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Chen, Hsiu-Cheng
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Huang, Yi-Jiun
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Wei, Kung-Hwa
In this study, we enhanced the power conversion efficiency (PCE) of perovskite solar cells by employing an electron transfer layer (ETL) comprising [6,6]phenyl-C-61-butyric acid methyl ester (PC61BM) and, to optimize its morphology, a small amount of the block copolymer polystyreneb-poly(ethylene oxide) (PS-b-PEO), positioned on the perovskite active layer. When incorporating 0.373 wt, % PS-b-PEO into PC61BM, the PCE of the perovskite photovoltaic device increased from- 9.4% to 13.4%, a relative increase of 43%, because of a large enhancement in the fill factor of the device. To\' decipher the intricate morphology of the ETL, we used synchrdtron grazing-incidence small-angle X-ray scattering for determining the PC61BM cluster site, atomic force microscopy and scanning electron microscopy for probing the-surface, and transmission electron microscopy for observing the aggregation of PC61BM in the ETL. We found that the interaction between PS-b-PEO and PC61BM resulted in smaller PC61BM dusters that further aggregated into dendritic structures in some domains, a result of the similar polarities of the PS block and PC61BM; this behavior could \'be used to tune the morphology of the ETL. The optimal PS-b-PEO-mediated PC61BM cluster size in the ETT, was 17 nm, a large reduction from 59 nin for the pristine PC61BM layer. This approach ofincorporating a small amount of nanostructured block copolymer into a fullerene allowed us to effectively tune the morphology of the ETL on the perovskite active layer and resulted in enhanced fill factors of the devices and thus their device efficiency.
美麗的背後　致命的慾望
(2016-09-25)
魏若芸
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Department of Communication and Technology
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傳播與科技學系
分析電影「霓虹惡魔」反映的人性與慾望，以及電影獨特的拍攝手法。
單身有罪　看清愛情真偽
(2016-09-25)
王韋翔
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Department of Communication and Technology
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傳播與科技學系
在一個只能容許情侶存在的社會，單身的人們必須在有限的時間裡，保衛自己身為人類的權利。
變身情人　看見內心的美
(2016-09-25)
陳昱彣
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Department of Communication and Technology
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傳播與科技學系
2015年上映的韓國愛情電影「愛上變身情人」，是描述每天都擁有不同身分的男主角在遇到女主角之後，兩人相戀的故事。
社群媒體時代　時尚大眾化
(2016-09-25)
陳昶安
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Department of Communication and Technology
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傳播與科技學系
走在時代的最前端，時尚向來是社會菁英用以彰顯身分的特權，然而近年來網路社群媒體的興起，卻對整個時尚產業和社會結構產生了不小的衝擊。
唱出真我　自然女聲蘇運瑩
(2016-09-25)
何家沂
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Department of Communication and Technology
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傳播與科技學系
發掘於選秀節目，富有特色的嗓音讓評審眼睛為之一亮，蘇運瑩帶著與眾不同的音樂恣意揮灑樂壇。
親愛的媽咪　愛的有限性
(2016-09-25)
凃湘羚
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Department of Communication and Technology
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傳播與科技學系
透過札維耶・多藍的電影「親愛媽咪」，展現母子間以暴烈狂狷的方式相愛著也傷害著彼此。
總編輯的話
(2016-09-25)
黃佳俐
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Department of Communication and Technology
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傳播與科技學系
本期為喀報第兩百四十五期，共有24篇稿件，其中包含藝文評論14篇、文化現象5篇、社會議題1篇、科技新知1篇、人物特寫1篇、照片故事1篇及自由創作1篇，側欄廣告為Media go講座的宣傳廣告。
流浪動物　不正常的流浪
(2016-09-25)
李瑞彥
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Department of Communication and Technology
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傳播與科技學系
流浪動物因人而流浪，也唯有人能夠解決流浪動物的問題。
數位新革命　聊天機器人
(2016-09-25)
朱倫君
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Department of Communication and Technology
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傳播與科技學系
知名社群網站Facebook在今年F8開發者大會，提出了一系列新發展與未來方向，其中Messenger Bot聊天機器人更是今年眾所矚目的焦點。
精心調製　世代價值剖析
(2016-09-25)
鄭懿君
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Department of Communication and Technology
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傳播與科技學系
台灣原創網路劇集「Mr. Bartender」以調酒作為基底，剖析世代價值觀之差異。